Euvolemia as a criterion of diuretic therapy efficacy in chronic heart failure: Literature review

Abstract

<jats:p>Chronic heart failure (CHF) is a typical outcome for all pathological processes affecting the cardiovascular system and is diagnosed in 1–2% of the population in developed countries. The strategy for managing patients with CHF involves the prescription of diuretics for the relief of volume retention syndrome in addition to pathogenetic pharmacotherapy. Considering the confl icting data concerning the effects of diuretics on the long-term prognosis and clinical course of CHF, a strict approach to the analysis of risk/benefit ratio is necessary while choosing a specific diuretic and determining its optimal dose and duration of use. The article reviews state-of-theart literature on the assessment of hydration status in patients with CHF. The euvolemia state, in which the optimal volume of fl uid is achieved in the body of a patient with CHF is viewed from the perspective of evaluating the efficacy and relevance of diuretic therapy.</jats:p>

Impact of connective tissue dysplasia on heart adaptation to exercise stress in young athletes

“…According to ultrasound examination, the variables of LV pump-function in young skiers at rest corresponded to the normal age-gender values for athletes [27,28]. Obtained results are in good agreement with the data of our previous studies [4,7,26] as well as findings by other researchers [9]. At the same time, the analysis of LV regional function at rest pointed at high level of the mechanical inhomogeneity in athletes.…”

“…Despite CTD is widely spread in population and may come up to 70-80 % of youths and adults, the rate of its distribution is higher in young athletes, than in non-athletic individuals of the same age [9,10]. Generally, subjects with CTD have asthenic type, high height and joint hypermobility [11].…”