2017
DOI: 10.17533/udea.acbi.329428
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Evaluación genotóxica de los plaguicidas cipermetrina y diazinón en tilapia roja (<i>Oreochromis</i> sp.)

Abstract: Con el propósito de evaluar la genotoxicidad y el efecto de la exposición continuada a dos plaguicidas en peces, se sometieron juveniles de tilapia roja (Oreochromis sp.) de 6,97 g de peso en promedio, a tres concentraciones de cipermetrina (0,04, 0,40 y 2,0 g/l) y a 16, 160 y 800 g/l de diazinón. Durante 24 días se tomaron 10 muestras de sangre para ser sometidas al ensayo cometa. Como control positivo se utilizó ciclofosfamida (Endoxan) a una concentración de 5 mg/l. En las tres concentraciones de cipermetri… Show more

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Cited by 3 publications
(1 citation statement)
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“…Studies carried out in females exposed to doses of 20 mg/kg/day-1 through oral ingestion of cypermethrin reported damage to the uterus and ovaries, in the latter with loss of oocytes and follicular cells, when intake is prolonged for 4 weeks there is a reduction in mass in the ovaries, in addition to causing toxicity in the liver and kidneys, which makes it difficult to detoxify and break down harmful chemicals such as pesticides (Kaur and Singh, 2021). It is also capable of generating teratogenic effects and hereditary defects caused by mutations in germ cells, these mutagenic effects may not manifest immediately but after several generations, which can increase the genetic load of the population, and subsequently generate carcinogenesis, due to multiple genetic alterations that trigger uncontrolled cell proliferation (Henao et al, 2005).…”
Section: Mutagenic Teratogenic and Carcinogenic Effect Of Cypermethrinmentioning
confidence: 99%
“…Studies carried out in females exposed to doses of 20 mg/kg/day-1 through oral ingestion of cypermethrin reported damage to the uterus and ovaries, in the latter with loss of oocytes and follicular cells, when intake is prolonged for 4 weeks there is a reduction in mass in the ovaries, in addition to causing toxicity in the liver and kidneys, which makes it difficult to detoxify and break down harmful chemicals such as pesticides (Kaur and Singh, 2021). It is also capable of generating teratogenic effects and hereditary defects caused by mutations in germ cells, these mutagenic effects may not manifest immediately but after several generations, which can increase the genetic load of the population, and subsequently generate carcinogenesis, due to multiple genetic alterations that trigger uncontrolled cell proliferation (Henao et al, 2005).…”
Section: Mutagenic Teratogenic and Carcinogenic Effect Of Cypermethrinmentioning
confidence: 99%