Evaluating Adherence of Health-Care Team to Standard Guideline of Colistin Use at Intensive Care Units of a Referral Hospital in Shiraz, Southwest of Iran

Vazin, Afsaneh; Karimzadeh, Iman; Zand, Atiyeh; Hatami-Mazinani, Nazafarin; Firouzabadi, Dena

doi:10.15171/apb.2017.047

Cited by 11 publications

(14 citation statements)

References 18 publications

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“…Furthermore, pharmacists can play a pivotal role in order to reach this objective. 39 Limitations of this study were short duration and involved those female patients only who attended the outpatient department. In order to validate these results the time duration and sample size of the study has to be increased and the population should include women from the large community.…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Use Evaluation in Genitourinary Tract Infections in Female Patients at a Tertiary Care Hospital

Alam¹,

Sharma²,

Dubey³

et al. 2020

jemds

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A B S T R A C T BACKGROUNDGenitourinary tract infections are some of the most common infections in females. These problems are a challenge in terms of diagnosis and treatment. The present study was conducted to evaluate the prescribing pattern in three of the most common types of female genitourinary tract infections. METHODSA prospective and observational study was conducted on genitourinary tract infections in female patients at the gynaecology outpatient department in a tertiary care university hospital. RESULTSMajority of the infected female patients were in 26 -35 years age group (31.8%) followed by 36 -45 years age group (25.9%). The common infection noticed was urinary tract infection (42.2%), followed by pelvic inflammatory disease (32.2%) and vaginitis (25.5%) in infected female patients. The types of antibiotics prescribed for urinary tract infection were aminoglycosides, fluoroquinolones, cephalosporins and penicillins. The commonly prescribed antibiotics for pelvic inflammatory disease were tetracyclines, azoles, fluoroquinolones and cephalosporins, and for vaginitis azoles and aminoglycosides. The most commonly prescribed class of antibiotics for urinary tract infection, pelvic inflammatory disease and vaginitis were fluoroquinolones (11.8%), azoles (11.8%) and aminoglycosides (15.7%), respectively. Oral route was the preferred mode of administration (71%), followed by rectal (suppositories, 17.2%) and topical (cream, 11.8%). CONCLUSIONSYoung married women in this urban Indian community have a high prevalence of genitourinary tract infections but seldom seek treatment. Education and outreach are needed to reduce the stigma, embarrassment and lack of knowledge related to genitourinary tract infections.

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Section: Discussionmentioning

confidence: 99%

Antibiotic Use Evaluation in Genitourinary Tract Infections in Female Patients at a Tertiary Care Hospital

Alam¹,

Sharma²,

Dubey³

et al. 2020

jemds

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“…Clinical pharmacist's suggestions regarding correcting colistin dose, based on patients clinical and paraclinical conditions were accepted by physicians in89% of cases. The acceptance rate of clinical pharmacist's suggestions was 100% in the case of incorrect continuation of empirical therapy [32].…”

Section: Designing Protocols Improving Drug Utilization and Cost Samentioning

confidence: 99%

Clinical and economic impacts of clinical pharmacists’ interventions in Iran: a systematic review

et al. 2019

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Objectives There are many studies about Iranian clinical pharmacists' interventions and their impacts on medication safety and cost. The aim of this study is to collect data and critically evaluate the clinical and economic effects of Iranian clinical pharmacist interventions and activities. To our best of knowledge, this research is the first review of publications about Iranian clinical pharmacists' interventions and activities. Evidence acquisition. Six online databases, including PubMed, Scopus, Medline, Cochrane Central Register of Controlled Trials, Cochrane Database of Systemic Reviews, and Google Scholar were searched using the terms 'BIranian^, Bclinical pharmacist^, 'adverse drug reactions^, Bmedication errors^, Bdrug interaction^, Bdrug utilization evaluation^, Bcost^, and Binterventions^for English studies conducted in Iran and described clinical pharmacist-initiated interventions, published before December 2018. The search and extraction process followed PRISMA guidelines. Observational or retrospective studies, clinical trials, congress abstracts, and case reports or case series were excluded. The search strategy after full-text review identified 39 articles matching the eligibility criteria. Results Thirty-nine articles were recruited. They included establishing pharmaceutical care in outpatient clinics and drug information centers (n = 4); prevention, detection, and management of adverse drug reactions(n = 4), designing protocols and improving drug utilization pattern(n = 16), prevention, detection, and management of medication errors (n = 11), and all clinical pharmacist services(n = 4). Most clinical pharmacist interventions and activities were regarding designing protocols, improving drug utilization pattern, as well as detection, prevention, and management of medication errors. About three-fourth (74.35%) of included studies were from either ambulatory care or in-patient settings in Tehran. The median (interquartile range) duration of intervention as well as follow-up phases was 9 (5) months. Conclusion Data of our review support the beneficial role of clinical pharmacists in the improvement of quality, safety, and efficiency of patients' pharmaceutical care in Iran.

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“…To reduce medication cost and to control the prevalence of antibiotic-resistant bacteria in the community, there is no doubt that physicians must optimize the use of antibiotics. Pharmacists can play a pivotal role in order to reach this objective 11. Drug Utilization Evaluation (DUE) is a method to understand the drug administration problems and to see if drugs are administrated appropriately 12.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of aminoglycosides utilization in intensive care units of a teaching hospital in southern Iran

Vazin¹,

Mirjalili²,

Asadi³

2019

Pharm Pract (Granada)

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Background:Inappropriate use of antimicrobial agents is one of the most important factors in inducing resistance and prolonged hospitalization as well as increase in patient mortality rate.Objective:The aim of this study was to evaluate aminoglycosides (AGs) usage pattern at intensive care units (ICUs) of Nemazee hospital Shiraz, Iran.Methods:In this cross-sectional study, the usage pattern of AGs was evaluated during 32 months. Guidelines for AGs usage were approved by the drug and therapeutic committee of the hospital, and criteria were developed to assess 11 parameters involving AGs therapy, such as proper indication for the use of the drug, dosage and duration of therapy. Clinical parameters, such as microbial culture and sensitivity, serum creatinine (SCr) and creatinine clearance, and white blood cell count were evaluated.Results:Ninety-five patients were recruited, 50 male and 45 females. In most patients (64%) the origin of infection was hospital and only in 36% of them, community was the source. Ventilator associated pneumonia (27%), central nervous system (25%) and urinary tract infection (10%) were the most important indications for AGs prescription. Scores of AGs usage at Nemazee hospital was calculated as 5.9 out of 11, which meant that in only 54% of cases AGs prescription was based on guideline proposed by the Department of Clinical Pharmacy of Nemazee Hospital.Conclusions:Non-adherence to the guidelines occurred frequently in the ICUs of Nemazee hospital. Prescription of loading dose, and AGs level measurement were not done and evaluating microbiological data was often neglected. Incorporating pharmacists in the health care team and holding training programs for physicians and nurses with the goal of raising awareness about the proposed guideline.

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Evaluating Adherence of Health-Care Team to Standard Guideline of Colistin Use at Intensive Care Units of a Referral Hospital in Shiraz, Southwest of Iran

Cited by 11 publications

References 18 publications

Antibiotic Use Evaluation in Genitourinary Tract Infections in Female Patients at a Tertiary Care Hospital

Antibiotic Use Evaluation in Genitourinary Tract Infections in Female Patients at a Tertiary Care Hospital

Clinical and economic impacts of clinical pharmacists’ interventions in Iran: a systematic review

Evaluation of aminoglycosides utilization in intensive care units of a teaching hospital in southern Iran

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