Evaluating blood perfusion of the corpus luteum in beef cows during fescue toxicosis1

Cline, G.F.; Muth-Spurlock, A. M.; Voelz, B.E.; Lemley, Caleb O; Larson, J. E.

doi:10.2527/jas.2015-9554

Cited by 6 publications

(2 citation statements)

References 43 publications

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“…The current data set shows similar results with average luteal volume in dairy cattle being ~8 cm 3 . In non‐pregnant beef cows, Cline, Muth‐Spurlock, Voelz, Lemley, and Larson () observed a luteal volume of ~5 cm 3 and a relative area of luteal blood perfusion of 2%. For the current data set, we observed a luteal volume of nearly 6 cm 3 and a larger per cent area of luteal blood perfusion, 6%–10% in pregnant and non‐pregnant beef cows.…”

Section: Discussionmentioning

confidence: 99%

Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle

Hart

Voelz

Brockus

et al. 2018

Reprod Domestic Animals

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Contents Production from the corpus luteum (CL) and/or hepatic steroid inactivation impacts peripheral concentrations of P4, which can alter reproductive performance. Our primary objective was to examine hepatic steroid inactivating enzymes, portal blood flow, and luteal blood perfusion at 10 days post‐insemination in pregnant versus non‐pregnant beef and dairy cows. Twenty early lactation Holstein cows and 20 lactating commercial beef cows were utilized for this study. At day 10 post‐insemination, hepatic portal blood flow and CL blood perfusion were measured via Doppler ultrasonography. Liver biopsies were collected and frozen for later determination of cytochrome P450 1A (CYP1A), 2C (CYP2C), 3A (CYP3A), uridine diphosphate‐glucuronosyltransferase (UGT) and aldo‐keto reductase 1C (AKR1C) activities. Pregnancy was determined at day 30 post‐insemination and treatment groups were retrospectively assigned as pregnant or non‐pregnant. Data were analyzed using the mixed procedure of SAS. Steroid metabolizing enzyme activity was not different (p > .10) between pregnant versus non‐pregnant beef or dairy cows. Hepatic portal blood flow tended (p < .10) to be increased in pregnant versus non‐pregnant dairy cows. Luteal blood perfusion was increased (p < .05) in pregnant versus non‐pregnant dairy cows. Pregnant dairy cows appear to have an increased rate of hepatic clearance of P4 in combination with increased synthesis from the CL. This could account for the lack of difference in peripheral P4 concentrations between pregnant and non‐pregnant dairy cows. This study highlights the relevance of further investigation into steroid secretion and inactivation and their impact on the maintenance of pregnancy in cattle.

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Section: Discussionmentioning

confidence: 99%

Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle

Hart

Voelz

Brockus

et al. 2018

Reprod Domestic Animals

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“…The chronic consumption of mycotoxin-contaminated forage tends to the weight loss of young cattle, decreasing the reproductive success of adult animals, milk yield, and tolerance to high temperatures (Porter and Thompson 1992;Cline et al 2016). Subsequent changes include the gangrenous ulcers appearance, shortness of breath and a heart rate turbulence (Stowe et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Single nucleotide polymorphism C994g of the cytochrome P450 gene possess pleiotropic effects in Bos taurus, L.

et al. 2022

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The chronic consumption of mycotoxin-contaminated forage tends to the weight loss of young cattle, decreasing the reproductive success of adult animals, milk yield, and tolerance to high temperatures. The aim of this paper was to study the eff ects of the SNP C994G in the CYP3A28 gene on the productive and reproductive characteristics of dairy and beef breeds. Cows were measured by body weight dynamics, exterior, reproduction, milk production traits, bone mineral density, bulls were analyzed estimating their progeny traits. Dairy cows received dietary betaine supplement with the measurement of homocysteine levels. Molecular genetic was performed by PCR-RFLP method. The effects of SNP C994G were shown in relation to the udder size, the constitution and birth weight of Abredin-Angus cows, as well as the fat and protein content of Ukrainian Red-and-White Dairy cows milk. The higher sensitivity of the GG genotype to less homocysteine level after the addition of betaine was shown. Given the identifi ed correspondence, pleiotropic eff ects of CYP3A28 gene can be concluded. A microscopic analysis of forage supported the findings in relation to greater efficiency of the CC genotype under conditions of low mycotoxins contamination, to which CYP3A28 is selective.

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The Symbiogenic Tango: Achieving Climate-Resilient Crops Via Mutualistic Plant-Fungal Relationships

Redman

Rodriguez

2017

Functional Importance of the Plant Microbiome

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Evaluating blood perfusion of the corpus luteum in beef cows during fescue toxicosis1

Cited by 6 publications

References 43 publications

Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle

Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle

Single nucleotide polymorphism C994g of the cytochrome P450 gene possess pleiotropic effects in Bos taurus, L.

The Symbiogenic Tango: Achieving Climate-Resilient Crops Via Mutualistic Plant-Fungal Relationships

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