Cognitive manufacturing utilizes cognitive computing, the industrial Internet of things (IoT), and advanced analytics to upgrade manufacturing processes in manners that were not previously conceivable. It enables associations to improve major business measurements, for example, productivity, product reliability, quality, and safety, while decreasing downtime and lowering costs. Considering all the facts that can prejudice the manufacturing performance in Industry 4.0, the cognitive load has received more attention, since it was previously neglected with respect to manufacturing industries. This paper aims to investigate what causes cognitive load reduction in manufacturing environments, i.e., human–computer interaction technologies that reduce the identified causes and the applications of cognitive manufacturing that use the referred technologies. Thus, a conceptual framework that links cognitive manufacturing to a reduction of the cognitive load was developed.