Evaluating Some of the Hematological Parameters for Helicobacter Pylori Infected Patients

Abstract

Helicobacter pylori are Gram-negative curved rods that habitats the gastric mucosa and considered as the leading causes of stomach ulcers and duodenal ulcers in humans. The main object of this study was to evaluate the influences of the bacteria on several hematological parameters. A total of 60 patients aged between 15 to 40 years were included in this study (30 male and 30 female) in addition to 30 healthy individuals from the same ages who were considered as a control group. Venous blood (4 ml) was obtained from the study population and investigated for complete blood count (CBC) using an automated hematology analyzer. The results revealed that there is a substantial decrease (p 0.01) in Hemoglobin (Hb), Red cell distribution width (RDW), and mean corpuscular hemoglobin (MCH) in patients compared to control. However, no significant difference in Red blood cells (RBCs), Hematocrit (HCT), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) in patients compared to control. Also, no significant differences were found in the white blood cell (WBC) between H. pylori infected and non-infected persons. Otherwise, there are significant differences (p 0.01) in lymphocytes, monocytes, granulocytes in the patients and healthy individuals. The results also found that there are significant statistical differences in some of the hematologic parameters among study groups according to their gender. The study concluded that Hb, RDW, lymphocytes, monocytes, granulocytes are decreased in H. Pylori infected patients suggesting that infection may have direct effects on blood parameters.