Energy renovations of the building stock are a paramount objective of the European Union (EU) to combat climate change. A tool for renovation progress monitoring is energy performance certificate (EPC) labelling. The present study tested the effect of different EPC label classifications on a national database, which comprises ~25,000 EPC values from apartment buildings, detached houses, office buildings, and educational, commercial, and service buildings. Analysing the EPC classes labelling resulting from four different EU methods, we estimated the annual renovation rates, costs, energy savings, and CO2 emissions reduction that would affect the national building stock if each of them was adopted, to fulfil the European Climate Target Plan by the year 2033. The ISO 52003-1:2017 two-point and one-point methods determined a very uneven distribution of renovation rates, from 0.45% to ~9%. Conversely, the Directive 15% recently proposed in COM/2021/802 with uniform rates determined smaller differences and standard deviation, not pushing renovations above 3.70%, namely a rate that once fine-tuned can stimulate realistic, yet effective renovation campaigns. The major differences in renovation rates provided by the studied methods show the need for a harmonized strategy such as the Directive proposal to enable achievement of European targets.