Evaluating the utility of computed tomography of the chest for gastric cancer staging

Nostedt, Jordan J.; Gibson-Brokop, Lindsay; Ghosh, Sunita; Seidler, Michael; McCall, Michael; Schiller, Daniel

doi:10.1503/cjs.000319

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…Similarly, for regular microvessels, mucosal capillaries show a uniform shape, closed loop, or open; for irregular microvascular structure, microvessels show open, closed loop, twisted, branched, and other shapes, with different shapes. Uniform, asymmetric distribution, and irregular arrangement; missing microvessels, manifested as the disappearance of microvascular structures, are replaced by white opaque substances [ 14 , 15 ]. According to the “VS classification system,” early gastric cancer can be diagnosed if any of the following is satisfied; otherwise, it is a non-cancerous lesion: (1) irregular surface microstructure (IMSP) and clear demarcation line (DL); (2) irregular Microvessels (IMVP) and specific lines of differentiation (DL) [ 16 ].…”

Section: Research On the Diagnosis Of Early Gastric Cancer Based On M...mentioning

confidence: 99%

The Diagnosis of Early Gastric Cancer Based on Medical Imaging Technology and Mathematical Modeling

Xiu

Ding²,

Li³

et al. 2022

Computational and Mathematical Methods in Medicine

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The key to reducing the mortality of gastric cancer is early detection, early diagnosis, and early treatment of gastric cancer. Early diagnosis of gastric cancer is the key to early detection and diagnosis of gastric cancer. Early diagnosis and treatment of gastric cancer is of great significance for improving the curative effect and reducing mortality of gastric cancer. The purpose of this paper is to study the diagnosis of early gastric cancer based on medical imaging techniques and mathematical modeling. The effect of W-DeepLab network-assisted diagnosis of images under white light was analyzed, and the value of Narrow Band Imaging and Blue Laser Imaging in the diagnosis of early gastric cancer was compared. Because Blue Laser Imaging endoscopy can clearly observe the demarcation line and microvascular morphology; but when using Narrow Band Imaging observation, part of the demarcation line and microvascular morphology is not observed. The results show that Blue Laser Imaging is brighter than Narrow Band Imaging’s endoscopic images, and it is easier to observe the microstructure of lesions under endoscopy, so as to accurately determine the nature of lesions.

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Section: Research On the Diagnosis Of Early Gastric Cancer Based On M...mentioning

confidence: 99%

The Diagnosis of Early Gastric Cancer Based on Medical Imaging Technology and Mathematical Modeling

Xiu

Ding²,

Li³

et al. 2022

Computational and Mathematical Methods in Medicine

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“…In a retrospective study, our group previously found an incidence of pulmonary metastases of 5.4%. 37 …”

Section: Discussionmentioning

confidence: 99%

“…In a retro spective study, our group previously found an inci dence of pulmonary metastases of 5.4%. 37 In a landmark study from Memorial Sloan Kettering Cancer Center in 1997, Burke and colleagues demon strated that staging laparoscopy spared 24 of 111 patients with gastric cancer the morbidity associated with under going a full laparotomy, as these patients were found to have M1 disease at laparoscopy that was not visible with other preoperative staging modalities. 38 Current guide lines in Alberta recommend that staging laparoscopy be considered for all patients with potentially resectable GEA.…”

Section: Discussionmentioning

confidence: 99%

A prospective Canadian gastroesophageal cancer database: What have we learned?

Purich

Skubleny

Ghosh

et al. 2023

cjs

Self Cite

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Background: Minimal literature exists on outcomes for Canadian patients with gastroesophageal adenocarcinoma (GEA). The objective of our study was to establish a prospective clinical database to evaluate demographic characteristics, presentation and outcomes of patients with GEA. Methods: Patients diagnosed with GEA were recruited from Jan. 30, 2017, to Aug. 30, 2020. Data collected included demographic characteristics, presentation, treatment and survival. A multivariable model for overall survival in patients treated with curative intent was created using sex, lymph node status, resection margin status, age and tumour location as variables. Results: A total of 122 patients with adenocarcinoma of the stomach or gastroesophageal junction were included. Median age was 65 years (interquartile range [IQR] 59–74), 70% of patients were male and 26% were born outside of Canada. Median follow-up time was 14.5 (IQR 8.0–31.0) months. Following staging computed tomography scanning, 88% of patients were deemed to have potentially resectable disease. Eighty-one (76%) received staging laparoscopy and 74 (61%) were treated with curativeintent surgery. Forty-six (62%) patients had nodal metastases. The median number of nodes harvested was 22 (IQR 18–30). The R0 resection margin rate was 82%. The 3-year overall survival for patients who received curative-intent treatment was 63% and 38% for all patients. On multivariable analysis, female sex (hazard ratio [HR] 3.88, p = 0.01), positive nodal status (HR 3.58, p = 0.02), positive margins (HR 3.11, p = 0.03) and tumour location (HR 3.00, p = 0.03) were associated with decreased overall survival. Conclusion: Many of the patients with GEA in this study presented with advanced disease, and only 61% were offered curative-intent surgery. A prospective multicentre national GEA database is now being established.

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Role of intraoperative patients positioning in endoscopic full-thickness resection of large gastric tumors under general anesthesia

Zhou

Xing²,

Chen³

et al. 2022

Front. Oncol.

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Full thickness endoscopic resection of large submucosal gastric tumors (>3 cm) is a big challenge for endoscopists. Issues include how to efficiently resect the lesion, obtain homeostasis, and suture the defect. There are no guidelines regarding the importance of patient position on the success of endoscopic resections in anesthetized patients. Typically, the patient is placed in left lateral position for the endoscopic therapy and during the procedure patient’s position is changed to maintain the tumor above the gastric fluids to prevent gastric juices and tumor or tumor fragments from falling into the peritoneal cavity in the event of perforation. This study emphasized the importance of planning the procedure to ensure that the patient’s position and anesthetist’s concerns are met and allow optimal access to the lesion for endoscopic resection. Prior to sedation the patient should be positioned so that the tumor is in the up position which also prevents blood obscuring the operative field, helps detect bleeding points for immediately hemostasis. In addition, due to gravitational effect, the resected tumor will fall into the gastric cavity exposing the root of the tumor making resection easier and reduce procedure time. Preplanning avoids unnecessary readjustment of positioning and improves the ease and safety of the procedure.

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Evaluating the utility of computed tomography of the chest for gastric cancer staging

Cited by 3 publications

References 16 publications

The Diagnosis of Early Gastric Cancer Based on Medical Imaging Technology and Mathematical Modeling

The Diagnosis of Early Gastric Cancer Based on Medical Imaging Technology and Mathematical Modeling

A prospective Canadian gastroesophageal cancer database: What have we learned?

Role of intraoperative patients positioning in endoscopic full-thickness resection of large gastric tumors under general anesthesia

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