Evaluation of 70% Glycolic Peels Versus 15% Trichloroacetic Peels for the Treatment of Photodamaged Facial Skin in Aging Women

Abstract

Superficial peels, such as 70% GA and 15% TCA, proved to be an effective treatment modality for photodamaged facial skin. Both acids contribute to improvement of the photodamaged skin's parameters. Glycolic acid increases skin's hydration faster.

Antiaging efficacy of a retinaldehyde‐based cream compared with glycolic acid peel sessions: A randomized controlled study

“…Novel retinol formulations have also been the focus of attention . In contrast, only a couple of recent studies has compared the efficacy and tolerability of various chemical peels . Yet, the comparative effects of the 2 treatments on photo‐damaged skin have never been evaluated in a randomized controlled study.…”

The efficacy and safety of a 70% glycolic acid peel with vitamin C for the treatment of photoaging

“…Kubiak et al compared 70% GA with 15% TCA peels and found clinical improvement in hydration and elasticity parameters as well as improvement in UV-induced post-inflammatory pigmentation in both groups. However, patients' satisfaction rates for GA peels were higher because of a superior side effect profile [5] . Table 2 is a comparative table of other studies evaluating the use of glycolic acid chemical peels in the treatment of photoaging.…”

Lactic and lactobionic acids as typically moisturizing compounds

“…The above data indicate that lactic acid, applied in the right concentration and at the appropriate pH of the solution used, and thus ensuring adequate bioavailability, has a slightly lower possibility of penetration through the skin than glycolic acid and by acting more superficially is also a substance that causes significantly less irritation. In addition, lactic acid is a substance naturally present in the skin, part of the NMF, which contributes significantly to its more caring effect on the skin …”