Abstract:The laboratory performance of this imaging probe is limited by the pinhole collimator performance and the necessity of working in minification due to the limited detector size. However, in clinical operative conditions, the CdTe imaging probe was effective in detecting SLNs with adequate resolution and an acceptable sensitivity. Sensitivity is expected to improve with the future availability of a larger CdTe detector permitting operation at shorter distances from the patient skin.
“…The aim of this work was to assess the laboratory performance of a prototype compact gamma camera (MediPROBE) based on a highspatial resolution semiconductor CdTe hybrid pixel detector, coupled with a CA mask. In a previous report we showed the performance of MediPROBE equipped only with pinhole collimators [18], and a MediPROBE without the lead shield, showing the housing for the interchangeable tungsten collimators and the chipboard with the CdTe hybrid pixel detector and the dedicated USB readout interface. In d) is shown a photo of the detector chipboard.…”
Section: Introductionmentioning
confidence: 99%
“…Single aperture collimators (e.g. pinhole) offer a geometric efficiency rapidly falling off at increasing longitudinal distances, and are not commonly adopted in such compact imaging probes; yet, they can enable a high spatial resolution since the image can be projected with magnification on the detector plane, or even in minification when a high resolution detector is available [18].…”
“…The aim of this work was to assess the laboratory performance of a prototype compact gamma camera (MediPROBE) based on a highspatial resolution semiconductor CdTe hybrid pixel detector, coupled with a CA mask. In a previous report we showed the performance of MediPROBE equipped only with pinhole collimators [18], and a MediPROBE without the lead shield, showing the housing for the interchangeable tungsten collimators and the chipboard with the CdTe hybrid pixel detector and the dedicated USB readout interface. In d) is shown a photo of the detector chipboard.…”
Section: Introductionmentioning
confidence: 99%
“…Single aperture collimators (e.g. pinhole) offer a geometric efficiency rapidly falling off at increasing longitudinal distances, and are not commonly adopted in such compact imaging probes; yet, they can enable a high spatial resolution since the image can be projected with magnification on the detector plane, or even in minification when a high resolution detector is available [18].…”
“…Many research groups around the world have been developing a range of hand-held or portable systems for medical gamma imaging [1,2,3,4,5,6,7,8,9,10,11,12]. To date, these smaller systems have all concentrated on a single imaging modality.…”
The development of low profile gamma-ray detectors has encouraged the production of small field of view (SFOV) hand-held imaging devices for use at the patient bedside and in operating theatres. Early development of these SFOV cameras was focussed on a single modality—gamma ray imaging. Recently, a hybrid system—gamma plus optical imaging—has been developed. This combination of optical and gamma cameras enables high spatial resolution multi-modal imaging, giving a superimposed scintigraphic and optical image. Hybrid imaging offers new possibilities for assisting clinicians and surgeons in localising the site of uptake in procedures such as sentinel node detection. The hybrid camera concept can be extended to a multimodal detector design which can offer stereoscopic images, depth estimation of gamma-emitting sources, and simultaneous gamma and fluorescence imaging. Recent improvements to the hybrid camera have been used to produce dual-modality images in both laboratory simulations and in the clinic. Hybrid imaging of a patient who underwent thyroid scintigraphy is reported. In addition, we present data which shows that the hybrid camera concept can be extended to estimate the position and depth of radionuclide distribution within an object and also report the first combined gamma and Near-Infrared (NIR) fluorescence images.
“…The preferred radiopharmaceutical for this procedure is 99m Tc labelled nanocolloid. During the operation a gamma probe is used for measuring the radioactive uptake in SLNs, however the introduction of imaging probes based on semiconductor detectors has been developed [5].…”
Section: Introductionmentioning
confidence: 99%
“…-1 -Examples of CdTe semiconductor detection for X-ray and gamma-ray imaging indicate that the newly developed semiconductor detectors have the potential to be competitive with the existing imaging devices based on scintillators [4,5].…”
Over the last two decades advances in semiconductor detector technology have reached the point where they are sufficiently sensitive to become an alternative to scintillators for high energy gamma ray detection for application in fields such as medical imaging. This paper assessed the Cadmium-Telluride (CdTe) XRI-UNO semiconductor detector produced by X-RAY Imatek for photon energies of interest in nuclear imaging. The XRI-UNO detector was found to have an intrinsic spatial resolution of <0.5mm and a high incident count rate capability up to at least 1680cps. The system spatial resolution, uniformity and sensitivity characteristics are also reported.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.