Evaluation of a collaborative care program for pulmonary hypertension patients: a multicenter randomized trial

Roustit, Matthieu; Chaumais, Marie‐Camille; Chapuis, Claire; Gairard-Dory, A.; Hadjadj, Caroline; Chanoine, Sébastien; Allenet, Benoît; Sitbon, Olivier; Pison, Christophe; Bedouch, Pierrick

doi:10.1007/s11096-020-01047-8

Cited by 6 publications

(24 citation statements)

References 26 publications

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“…Studies in the elderly focused on cognitive and physical capacities, falls and mortality rate (33,34,36,37). Clinical endpoints assessed in studies also included disease balance mostly focusing on one disease (39,43,46,49). Five interventions evaluated cost-effectiveness of their model through health resource use and cost (e.g.…”

Section: Results Of Individual Studiesmentioning

confidence: 99%

“…Five interventions evaluated cost-effectiveness of their model through health resource use and cost (e.g. hospitalizations type and rate, consultations, medication cost) (33,36,39,43,49). Psychosocial criteria such as depression (35,44), anxiety (44), emotional distress (49) and patient's or caregivers' quality of life (35-37, 39, 44, 49) were assessed.…”

Section: Results Of Individual Studiesmentioning

confidence: 99%

“…GAIN intervention showed a 20% reduction in the incidence of grade 3 or greater chemotherapy-related toxicities (41). Of the two studies that assessed patient medication adherence, Zheng et al study showed improvement (moderate to high) to antiepileptic medication adherence (39,44).…”

Section: Results Of Individual Studiesmentioning

confidence: 99%

“…After removal of the 24 duplicates and 9 protocols, 33 articles were assessed for eligibility. In the end, 16 articles were selected and included in the systematic review (32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48). Figure 1 shows the article selection process.…”

Section: Study Selectionmentioning

confidence: 99%

“…Of the selected studies, 10 involved elderly patients, including 6 living in nursing homes (33,34,37,38,47,48). The interventions for adult patients that did not target the elderly focused on a speci c chronic pathology (diabetes (43,49), epilepsy (44), dementia (35), chronic pain treated with opioids (46) or pulmonary hypertension (39)).…”

Section: Study Characteristicsmentioning

confidence: 99%

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Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: a systematic review

ZAIJ

MAIA

Leguelinel-Blache

et al. 2023

Preprint

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Background Preventable harm in healthcare is a growing public health challenge. In addition to the economic costs of safety failures, adverse drug events (ADE) may lead to complication or even death. Multidisciplinary care team involving a pharmacist appears to be an adequate response to prevention of adverse drug event. This systematic review aims to identify and describe multidisciplinary planned team-based care involving at least one pharmacist to limit or prevent adverse drug events in the adult patients. Methods To determine the type of interprofessional collaboration to prevent adverse drug event in which a pharmacist was involved, we conducted a systematic review of the literature of randomized controlled trials. Two independent reviewers screened trials in three databases: Medline, Web of Science, ScienceDirect. Prospective studies of at least three different health professionals’ interventions, one of whom was a pharmacist in the last five years were included. Two reviewers performed data extraction and quality appraisal independently. We used TIDieR checklist to appraise articles quality. Results In total 803 citations were retrieved, 34 were analysed and 16 full-text articles were reviewed. Only 3 studies published an implementation evaluation. More than half of the interventions (62%) targeted elderly patients including 6 whom lived in nursing homes. Studies outcomes were heterogeneous, and we did not perform a statistical analysis of the impact of these interventions. Most teams are composed of a physician/pharmacist/nurse trio (94%; 100%; 88%). Half of the teams were composed of the primary care physician. Other professionals were included such as physical therapists (25%), social worker (19%), occupational therapists (12%), and community health educator (6%). Multidisciplinary medication review was the most common intervention and was generally structured in four steps: data collection and baseline assessment, appraisal report by health professionals, a multidisciplinary medication review meeting and a patient follow-up. Conclusions The most common multidisciplinary intervention to prevent ADE in the adult population is the multidisciplinary drug review meeting at least the physician/pharmacist/nurse trio. Interventions target mostly elderly people in nursing homes, although complex chronic patients could benefit from this type of assessment. Trial registration PROSPERO registration: CRD42022334685

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Section: Results Of Individual Studiesmentioning

confidence: 99%

Section: Results Of Individual Studiesmentioning

confidence: 99%

Section: Results Of Individual Studiesmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

See 3 more Smart Citations

Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: a systematic review

ZAIJ

MAIA

Leguelinel-Blache

et al. 2023

Preprint

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Patient Preferences for Pharmacy Services: A Systematic Review of Studies Based on Discrete Choice Experiments

Riboulet,

Clairet,

Bennani

et al. 2023

Patient

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A Descriptive Study of a Clinical Pharmacist’s Role in the Outpatient Pulmonary Hypertension Clinic in the United States (CliPR-PH)

Funtanilla

Lee

Kim

et al. 2023

Preprint

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BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare disease affecting the heart and lungs. Median survival was 2.8 years historically, but prognosis improved with the advances of PAH therapy. It is currently not standard of care for clinical pharmacists to be a part of the interdisciplinary care team in outpatient PH clinics to help manage patients' drug regimens, and there is limited literature that has explored the impact of clinical pharmacists on patient-related processes and outcomes. The goal of the CliPR-PH study is to characterize the activities of the clinical pharmacist as a member of the interdisciplinary team. METHODS: CliPR-PH was a retrospective, descriptive, single-center cohort study of patients ≥ 18 years, diagnosed with pulmonary hypertension, and managed by a clinical pharmacist practicing under a collaborative practice agreement between January 1, 2018 and July 31, 2020. Patients were excluded from the study if they were not on any PAH medications at the time of pharmacist encounter. RESULTS: Sixty patients were included in the analysis and 331 clinical pharmacist interventions were documented over the study period. Interventions were regarding selexipag [88 (26.6%)], sildenafil [74 (22.4%)], tadalafil [46 (13.9%)], prior authorization (PA) completions [127 (38.4%), PA troubleshooting [43 (13.0%)], and 'Other' [49 (14.8%)]. CONCLUSION: Clinical pharmacists can play an important role in closely monitoring patients during the medication titration phase and ensure prior authorizations are approved in a timely manner as part of the interdisciplinary team in the outpatient PH clinic setting using a collaborative practice model approach.

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Evaluation of a collaborative care program for pulmonary hypertension patients: a multicenter randomized trial

Cited by 6 publications

References 26 publications

Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: a systematic review

Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: a systematic review

Patient Preferences for Pharmacy Services: A Systematic Review of Studies Based on Discrete Choice Experiments

A Descriptive Study of a Clinical Pharmacist’s Role in the Outpatient Pulmonary Hypertension Clinic in the United States (CliPR-PH)

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