Evaluation of a method for converting venous values of acid-base and oxygenation status to arterial values

Toftegaard, Marianne; Rees, Stephen Edward; Andreassen, Steen

doi:10.1136/emj.2007.052571

Cited by 39 publications

(49 citation statements)

References 15 publications

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“…This method has been shown to have good accuracy and precision when calculating arterial pH (bias¡2SD: 0.002¡0.027) or arterial PCO 2 (bias¡2SD: -0.04¡0.52 kPa) [8]. For calculation of PO 2 , precision was dependent on the oxygenation level, such that for peripheral oxygen saturation (Sp,O 2 ) values .96% the method was not considered useful for calculating PO 2 , and for Sp,O 2 f96% the accuracy and precision of calculated PO 2 was 0.21¡1.85 kPa (bias¡2SD) [8].…”

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confidence: 99%

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Converting venous acid–base and oxygen status to arterial in patients with lung disease

Rees¹,

Hansen²,

Toftegaard³

et al. 2009

Eur Respir J

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The aim of the present study was to evaluate a method for calculating arterial values of pH, carbon dioxide tension (PCO 2 ) and oxygen tension (PO 2 ) from peripheral venous values.In total, 40 patients were studied. Arterial and peripheral venous blood were sampled at a department of respiratory diseases. Arterial values were calculated from venous, and measured and calculated values of arterial pH, PCO 2 and PO 2 were compared.Measured and calculated values of pH and PCO 2 correlated well, with the difference between them having a very small bias and standard deviation (pH -0.001¡0.013, PCO 2 -0.09¡0.28 kPa) within those considered acceptable for laboratory equipment and clinical practice. All but four patients had peripheral oxygen saturation (Sp,O 2 ) f96%, and for these measured and calculated PO 2 correlated well, with a difference such that the bias and standard deviation suggested that calculated PO 2 may be clinically useful (PO 2 0.11¡0.53 kPa).The present study evaluates a method for calculating arterial pH, carbon dioxide tension and oxygen tension from venous blood. It has been shown that arterial pH and carbon dioxide tension can be calculated precisely, and that oxygen tension can be calculated with reasonable precision in the vast majority of patients. This method might be useful in reducing the need for painful arterial punctures.

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confidence: 99%

“…The previous evaluation of this method was in patients admitted to the wards of either ICUs or a department of pulmonary medicine, and these patients were studied under experimental conditions [8]. These experimental conditions differ from routine clinical practice in medical departments in several important respects.…”

mentioning

confidence: 99%

Converting venous acid–base and oxygen status to arterial in patients with lung disease

Rees¹,

Hansen²,

Toftegaard³

et al. 2009

Eur Respir J

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“…Recently, arterial and venous blood gas samples were compared in patients with hypercapnia and respiratory acidosis due to chronic obstructive pulmonary disease (COPD). In some of these studies, correlation was found between levels of pH (r= 0.934, r= 0.828, r= 0.826), Arterial pCO 2 (r= 0.908, r= 0.877, r= 0.838) and HCO 3 (r= 0.927, r= 0.896) (p<0.001) [3,11,12,15]. In another study performed in patients with respiratory acidosis, correlation values were found as p<0.001 between arterial and venous blood gas samples regarding pH (r= 0.864), pCO 2 (r= 0.761), HCO 3 (r= 0.749) and also including PaO 2 (r= 0.702) [22].…”

Section: Discussionmentioning

confidence: 98%

“…In these studies; significant correlation between arterial and venous pH and bicarbonate (HCO 3 ) values in case of metabolic acidosis and it was stated that venous blood gas samples had showed the correct degree of acidosis [5][6][7][8][9][10][11]. In patients with terminal respiratory failure and respiratory acidosis, it was stated that venous pH could be used instead of arterial pH and venous partial pressure of carbon dioxide (pCO 2 ) was sufficient to monitor hypercarbia [3,[12][13][14][15]. Patients with respiratory alkalosis were frequently encountered in clinical practice, and repeated blood gas samples are needed during the follow-up of these patients.…”

Section: Introductionmentioning

confidence: 99%

Can venous blood gas values be used instead of arterial blood gas values in respiratory alkalosis?

Kozacı¹,

Gungor²,

Ay³

et al. 2014

Turk J Bioch

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“…Therefore, before collecting arterial blood, especially in surgical patients, peripheral blood can be collected from the patient allowing blood gases and oxygenisation to be assessed. Venous blood can be collected from a central vein such as the jugular vein, anterior vena cava or pulmonary artery 9,[13][14][15][16][17] . Pang et al 14 9,17 .…”

mentioning

confidence: 99%

Comparison of the Effects of Spontaneous and Mechanical Ventilation on Blood Gases During General Anaesthesia in Dogs

Güzel¹,

Yıldar²,

Karabağli³

et al. 2013

Kafkas Univ Vet Fak Derg

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SummarySpontaneous ventilation during general anaesthesia leads to respiratory depression and atelectasis. Mechanical ventilation increases tidal volume and eliminates atelectasis. The study material consisted of a total of 20 dogs of different breed, age and gender. Dogs were divided into two groups, consisted of 10 dogs. The first group was established as the spontaneous ventilation (SV) group, while the second group was the mechanical ventilation (MV) group. For induction of anaesthesia, propofol was administered to both groups via intravenous injection at a dose of 6 mg/kg. Blood samples were collected from all dogs in 5 minutes after propofol administration. This period was determined as Minute 0 (T 0 ). In both groups, inhalation anaesthesia was continued with isoflurane. Venous blood samples were collected from dogs in the SV and MV groups at 15 (T 15 ), 30 (T 30 ) and 60 (T 60 ) minutes. Heart rate, respiratory rate, SpO 2 , body temperature and blood gases were monitored. Statistical evaluation of the study was carried out using the Repeated Measures Analysis of Variance method. The results obtained showed that there was no statistically significant difference between the SV and MV groups regarding the examined parameters. However, in the assessments within the group, results obtained from the dogs in the MV group were more reliable from the point of view of the patients remaining stable throughout anaesthesia. Keywords: Spontaneous ventilation, Mechanical ventilation, Blood gases, Dog Köpeklerde Genel Anestezi Sürecinde Spontan ve Mekanik Ventilasyonun Kan Gazları Üzerine Etkilerinin Karşılaştırılması ÖzetGenel anestezide spontan ventilasyon, solunumun baskılanmasına ve atelektaziye yol açar. Mekanik ventilasyon tidal volümü artırır ve atelektaziyi giderir. Çalışma materyalini, farklı ırk, yaş ve cinsiyetteki toplam 20 köpek oluşturdu. Olgular, her grupta 10 köpek olacak şekilde 2'ye ayrıldı. İlk grup spontan ventilasyon (SV), ikinci grup mekanik ventilasyon (MV) grubu olarak belirlendi. Anestezi indüksiyonunda her iki gruba, propofol 6 mg/kg'dan intravenöz enjeksiyonla verildi. Tüm köpeklerden, propofol enjeksiyonunu takip eden 5. dakikada kan örnekleri alındı. Bu süre 0. dakika (T 0 ) olarak değerlendirildi. Her iki grubun inhalasyon anestezisi izofloranla sürdürüldü. SV ve MV grubundaki olgulardan 15. dakika (T 15 ), 30. dakika (T 30 ) ve 60. dakika (T 60 )'larda venöz kan örnekleri alındı. Kalp atım sayısı, solunum sayısı, SpO 2 , vücut ısısı ve kan gazları monitörize edildi. Çalışmanın istatistiki değerlendirmesi Tekrarlı Ölçüm Varyans Analizi metodu ile yapıldı. Elde edilen bulgular, incelenen parametreler yönünden SV ve MV grupları arasında istatistiki anlamda önemli bir fark olmadığını gösterdi. Ancak grup içi değerlendirmelerde, MV grubundaki köpeklerden elde edilen sonuçların, hastaların anestezi süresince stabil kalmaları açısından daha güvenilir olduğu sonucuna ulaşıldı.

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Evaluation of a method for converting venous values of acid-base and oxygenation status to arterial values

Cited by 39 publications

References 15 publications

Converting venous acid–base and oxygen status to arterial in patients with lung disease

Converting venous acid–base and oxygen status to arterial in patients with lung disease

Can venous blood gas values be used instead of arterial blood gas values in respiratory alkalosis?

Comparison of the Effects of Spontaneous and Mechanical Ventilation on Blood Gases During General Anaesthesia in Dogs

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