Evaluation of a water-soluble contrast agent for the conservative management of adhesive small bowel obstruction in pediatric patients

Lee, Chee-Yew; Hung, Min-Hsuan; Lin, Lung–Huang; Chen, Der-Fang

doi:10.1016/j.jpedsurg.2014.11.034

Cited by 16 publications

(9 citation statements)

References 23 publications

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“…This was not the same findings found by Lee CY et al, who found that the recurrence rate was higher in the gastrografin group compared to the surgical group (55% vs. 38%), the need for surgery for the recurrent episodes was much lower (17% vs. 33%). [10][11][12][13] In this study, five cases out of fourteen (35%) of gastrografin group experienced recurrence, all managed conservatively compared to two cases out of six (33%) treated surgically that needed exploration for their recurrence. The limitation of this study was both small sample size and absence of control group.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of the role of oral gastrografin in management of simple adhesive small bowel obstruction in children

Eltayeb

Abufaddan

2019

Int Surg J

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Background:The risk of post-operative adhesive small intestinal obstruction is highest during the first post-operative year. Bowel injury during adhesiolysis increases the post-operative morbidity. Consequently, the conservative management of small bowel obstruction has considerable interest. The aim of this study was to evaluate the therapeutic role of gastrografin in the management of small bowel obstruction. Methods: All patients with simple adhesive small bowel obstruction will be included and treated conservatively for 48hours unless there was evidence of strangulation. After the first 48 hours all the patients were given oral gastrografin unless improved or signs of strangulation arise. The evaluating parameters are the success rate, time to start full oral feeding and total duration of hospital stay. Results: Twenty-five cases were included in which two of them developed clinical evidence of strangulation during the first 48hours and were explored. Three cases improved on the conservative treatment. The remaining twenty cases were given oral gastrografin. Fourteen cases out of twenty showed the contrast dye in their large bowel by 24hours. Those 14 cases tolerated full oral feeding earlier and had shorter hospital stay than the remaining 6 cases that declared treatment failure and underwent surgical exploration. Conclusions: The use of gastrografin as a preliminary step of non-surgical treatment of simple adhesive intestinal obstruction may be helpful. However, further randomized study on a large number of patients was needed.

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Section: Resultsmentioning

confidence: 99%

Evaluation of the role of oral gastrografin in management of simple adhesive small bowel obstruction in children

Eltayeb

Abufaddan

2019

Int Surg J

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“…Water-soluble contrast media are valuable in predicting the need for surgery for ABO in the small intestine [11]. They promote the shift of uid into the intestinal lumen and increase the pressure gradient across an obstructive site, reducing edema of the bowel wall and improving motility of the bowel [12].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Role of Water-Soluble Contrast Administration in Management of Patients with Adhesive Intestinal Obstruction

Shaban

Abu-Elela

Faisal

et al. 2021

Preprint

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Background: Adhesive intestinal obstruction is a common post-operative cause of hospitalization. This study aims to evaluate the oral administration of water-soluble contrast on the outcome of patients with adhesive intestinal obstruction in regard to recovery, operative rate and hospital stay.Methods: In this prospective randomized trial, patients were randomized into two groups: gastrografin (GG) and traditional treatment group (TT). in the gastrografin group (GG)after stomach was emptied through a nasogastric tube, the water soluble contrast follow-through was performed within 24 h of hospital admission using 100 mL of 76% gastrografin injected through the nasogastric tube and erect ,supine abdominal x-ray was taken(at 8,12,24h)later. The endpoints of the study were to evaluate the time interval between admission and relief of obstruction, the length of hospital stay and the need for surgery. Results: Fifty-four patients with a mean age 45 ±2.4years, 25(46.3%) males and 29(53.7%) females. The number of patients who were successfully conservatively treated in the gastrografin group was 22(81.5%), which was significantly higher than 13(48.1%) in the traditional group. among these patients, mean hospital stay in gastrograffin group was 31.3±4.5 hours, which was significant shorter than 48.9±8.2hours in traditional group(p=0.004). Conclusions: Administration of an oral water-soluble contrast agent in postoperative adhesive bowel obstruction helps in the earlier resolution of the obstruction, decreases the length of hospital stay and the need for surgery.

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“…In adult and pediatric literature, it is a well described method in dealing with ABSO and has been shown to decrease the need for repeat operation and stay days in these patients [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Oral Water-Soluble Contrast Agent as the Definitive Treatment of Uncomplicated Adhesive Bowel Obstruction in Infants and Neonates

Middleton¹,

Banieghbal²

2019

SARJAMS

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Aim: To assess feasibility, safety and long-term outcome of a water-soluble contrast agent (Gastrografin™) in surgical neonates/infants who present with ABSO. Method: 18 Neonates, who continued to exhibits signs of intestinal obstruction after one week post surgery, were given 1-2 mls/kg of oral Gastrografin for 5-8 days. Result: All but one patient could be fed within 12 hours and discharged home soon afterwards. A single patient retuned 6 months later with ABSO and was similarly treated again. There was no mobility or mortality due to this technique. Main Conclusion: Gastrografin contrast give orally can result in relief of ABSO, as similarly described in adult and older children.

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Evaluation of a water-soluble contrast agent for the conservative management of adhesive small bowel obstruction in pediatric patients

Cited by 16 publications

References 23 publications

Evaluation of the role of oral gastrografin in management of simple adhesive small bowel obstruction in children

Evaluation of the role of oral gastrografin in management of simple adhesive small bowel obstruction in children

Evaluation of the Role of Water-Soluble Contrast Administration in Management of Patients with Adhesive Intestinal Obstruction

Oral Water-Soluble Contrast Agent as the Definitive Treatment of Uncomplicated Adhesive Bowel Obstruction in Infants and Neonates

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