Evaluation of AGP, SSA concentration with the relationship of antibody titer in broiler chicken vaccinated with IBD virus

Abstract

Gumboro or Infectious bursal disease (IBD) is one of the most important diseases in poultry industry. IBD causes economic losses as a result to mortality and reduction in performance and medicine expenses(de S. B. Fróes et al., 2018). IBD is Severe acute disease of 3-6-week-old birds is associated with high mortality, but a less acute or subclinical disease is common in 0-3-week-old birds (Sali, 2019). IBD virus causes lymphoid depletion of the bursa and if this occurs in the first 2 weeks of life, significant depression of the humoral antibody response may result. The current study aims to measurement of antibody titer and acute phase proteins (AGP and SSA) in broiler chickens subjected to the Gumboro vaccine to explore the intensity of the vaccine strain and the response of both the early innate immune response and late humoral immune responses (antibody titers) raised against the vaccine. A handed Ross 308 chicks were divided into three groups, control, intermediate and intermediate plus vaccine. At 10 days old, the chicks were vaccinated and then blood samples collected at 12, 24 hours, and 10 and 15 days.