“…Patients with irritable bowel syndrome often have accelerated intestinal transit, particularly through the proximal colon (Vassallo et al, 1992). Patients with active ulcerative colitis have also been found to have significantly faster small intestinal transit and colonic transit than controls (Hebden et al, 2000), contradicting results obtained by others (Hardy et al, 1987). It has been reported that many patients that underwent an ileocaecal resection (Munkholm et al, 1993) showed a shorter dosage form stagnation at the ileocaecal junction, thereby reducing the overall small intestinal transit time (Fallingborg et al, 1998).…”