Evaluation of angiotensin-converting enzyme-inhibitory activity in abalone viscera fermented by Lactobacillus casei 001

Enhancement of the Antihypertensive Effect of Fermented Sargassum horneri with Lactiplantibacillus pentosus SN001

“…In the SHR test, the blood pressure levels in the fermented group showed lower compared to those of the control group. In abalone viscera, L. casei 001 fermentation has been reported to reduce blood pressure levels in AI-injected ddY mice and SHR, and homalin has been identified as a component involved in blood pressure reduction [20]. Therefore, in this study, we isolated and purified similarly fermented S. horneri and performed NMR measurements to identify components with ACE inhibitory activity.…”

“…The mice were randomly divided into three groups of five mice per group, control, unfermented and fermented group. The blood pressure test was a modified version of an existing protocol [20]. Unfermented (1500 mg/kg bw) and fermented (1500 mg/kg bw) extracts dissolved in distilled water were administered directly into the stomach using a sonde, and the mice were placed in a measuring gauge.…”

Antihypertensive effects of abalone viscera fermented with Lactiplantibacillus pentosus SN001 via angiotensin-converting enzyme inhibition

“…LAB can easily and reproducibly ferment fish visceral waste ( Váquez et al, 2011 ), and fermentation by LAB has been shown to have antihypertensive ( Garbowska, Pluta, & Berthold-Pluta, 2019 ) and cholesterol-lowering effects ( El-Dein et al, 2021 ). Additionally, Lactobacillus pentosus has been reported to have probiotic properties ( Guantario et al, 2018 ) and angiotensin-converting enzyme (ACE) inhibitory activity ( Fujimura, Shimura, Nagai, & Hamada-Sato, 2021 ). Thus, foods developed through the fermentation of LAB are expected to have various applications.…”

“…Fermentation of abalone viscera with LAB is expected to have beneficial effects, particularly with regard to suppression of blood pressure elevation. In a previous study, abalone viscera fermented with L. casei 001 was shown to have inhibitory effects on blood pressure elevation in vivo ( Fujimura et al, 2021 ), suggesting that abalone viscera fermented with LAB may be a promising functional food material for blood pressure control. However, the applicability of this approach to other species of LAB and the effects of ingesting fermented abalone viscera powder on blood components, such as glucose and triglyceride levels, have not been confirmed.…”

A multi-functional survey of the properties of Lacticaseibacillus paracasei subsp. tolerans NOC-122, Levilactobacillus parabrevis NOC-111 and Latilactobacillus curvatus NOC-110

“…Lactic acid bacteria (LAB), isolated from various fermented food products, and their metabolites have attracted much attention for their many functional properties. The main functional property here is the probiotic properties of some LAB and their ability to produce different compounds with antioxidant, anti-hypertensive, antibacterial, antiviral, anticarcinogen, anti-inflammatory or antimutagen activities [1][2][3]. The functional compounds produced by LAB can affect food products not only in terms of health but also physically and sensually.…”