Evaluation of anti-varicella antibody in young women before their marriage: A sero-epidemiologic study in Iran

Pourahmad, Morteza; Davami, Mohammad Hassan; Jahromi, Abdolreza Sotoodeh

doi:10.1016/j.jcv.2010.04.015

Cited by 15 publications

(14 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…reported that the PPV of women with positive history of chickenpox was 79.5% and the NPV of those with negative history of chickenpox was 30.5% (13). In contrast to our finding, Talebi-Taher et al obtained a NPV of 13.8% as a poor predicator of Varicella immunity (15).…”

Section: Discussioncontrasting

confidence: 99%

“…In a similar study conducted in Iran by Pourahmal et al, 72.7% of women who intent to marry were seropositive for VZV (13). In study of Majidi et al, the prevalence of anti-VZV antibody in women before marriage in Sanandaj was 72.1% (7).…”

Section: Discussionmentioning

confidence: 87%

“…Women before and during pregnancy should be screened for VZVantibody using laboratory tests. If women do not have enough immunity against VZV, they should receive either immunoglobulin or antiviral therapy (13). Determining the immune status of women to VZV before marriage or pregnancy is useful for healthcare system to protect mother and baby from possible complications of varicella.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

et al. 2016

View full text Add to dashboard Cite

Background and Aims: Varicella-zoster virus (VZV) infection among pregnant women can cause a serious threat to the health of mother and fetus. Varicella is clearly less dangerous for immunized mothers. The aim of this study was to determine the prevalence of VZV antibody among women before marriage. Materials and Methods: This cross-sectional study was conducted on 300 women of childbearing age who referred to Yazd clinic for premarital screening. The enzyme-linked immunosorbent assay (ELISA) technique was performed to detect antibodies against VZV. Demographic characteristics of each participant, including age, educational level, place of residence, family and self-reported history of chickenpox were collected by a questionnaire. Results: Mean age of women under study was 23±5.4 years that 223 participants (73.7%) were seropositive, and 77 cases (25.7%) were seronegative for anti-VZV antibody, while 2 (0.6%) subjects had an equivocal result. A higher immunity ratio (86.4%) was found among older women (33-44 years). Data showed no significant correlation between immunity to VZV and age, educational level, place of residence. A statistically significant association was found between the family history, self-reported history of chickenpox and immunity to VZV. The positive and negative predictive values for self-reported history of chicken pox were 97.1% and 81.1%, respectively. Conclusions: A significant number of women before marriage had no immunity to VZV. They are in risk of getting varicella, which can cause serious complications in mother and fetus. It, therefore, seems necessary to screen women of child-bearing age for anti-VZV antibody. In addition, vaccination against VZV in Iranian women before marriage can be a good recommendation.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 87%

mentioning

confidence: 99%

See 1 more Smart Citation

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

et al. 2016

View full text Add to dashboard Cite

show abstract

“…While we have some epidemiological reports on Varicella in Iranian adults [11][12][13][14][15][16][17], only two studies have been conducted to find out the prevalence of Varicella immunity and the value of self-reported history of infection in medical students [18,19]. Therefore, this study aimed to determine the seroprevalence of Varicella zoster virus (VZV) antibodies as well as the value of self-reported history of infection in the students' subpopulation.…”

Section: Discussionmentioning

confidence: 99%

“…Also, the data from the questionnaire and serological survey were analyzed to determine history of Varicella and seropositivity among 3 student groups. It is recommended to consider uncertain history of Varicella as negative in the occupational health care setting, so we added unknown histories to the negative history category [16].…”

Section: Laboratory Data Gathering and Analysismentioning

confidence: 99%

Seroepidemiology of Varicella and value of self-reported history of Varicella infection in Iranian medical students

Allami¹,

Mohammadi²,

Najar³

2014

International Journal of Occupational Medicine and Environmental Health

View full text Add to dashboard Cite

Objectives: We conducted this study to assess the seroprevalence of Varicella zoster virus (VZV) antibodies in a group of Iranian medical sciences students that were at risk of Varicella and the value of self-reported history as a predictor of immunity. Material and Methods: 255 medical, nursing and obstetrics students who had not entered as a student or worked in a hospital from 3 different schools were enrolled in the study in 2012 (Qazvin province, Iran). Demographics and other information as well as the history of Varicella were obtained through a self-administered questionnaire. Blood samples were collected to determine the Varicella IgG levels via an enzyme-linked immunosorbent assay. A statistical analysis was performed by calculating prevalences and their 95% confidence intervals. Sensitivity, specificity, positive and negative predictive values, Cohen's kappa and positive and negative likelihood ratios of recalled history were determined. p < 0.05 was considered statistically significant. Results: The mean age of participants was 21.3±4.3 years. Seropositivity rate was 74.5%. The relationships between marital status, number of family members, and acquired VZV history with immunity against the virus were statistically significant. The overall rate of reported history was 57%. The positive and negative predictive values of self-reported history of Varicella were 91% and 47.3%, respectively. Conclusions: Immunization of students of Iranian medical sciences seems logical in the near future. Also, they should be tested for Varicella immunity regardless of the history of previous infection.

show abstract

Varicella Vaccines

Gershon¹,

Marin²,

Seward³

2018

Plotkin's Vaccines

View full text Add to dashboard Cite

Evaluation of anti-varicella antibody in young women before their marriage: A sero-epidemiologic study in Iran

Cited by 15 publications

References 16 publications

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

Seroepidemiology of Varicella and value of self-reported history of Varicella infection in Iranian medical students

Varicella Vaccines

Contact Info

Product

Resources

About