Evaluation of Antibacterial Activity of Artemisia vulgaris Extracts

Abstract

Plants have been and still are the main source of a variety of drugs. Due to this trend, there is a need to investigate plants and determine if they possess any medicinal property. In this study, medicinal compounds in the stem, root and shoot of Artemisia vulgaris were extracted sequentially via Soxhlet extract using petroleum ether, acetone and 90% ethanol on water respectively. Antimicrobial activity of these extracts was tested against Staphylococcus aureus (SA), Methicillin Resistant Staphylococcus aureus (MRSA) and Bacillus subtilis (BS) using the disc diffusion method. Whereas acetone extract exhibited high antimicrobial activity (5 mg mLG against S. aureus and no activity against MRSA). Diminished or lack of antibacterial activity from the ethanol extract reported in this study conflicts previous studies which report higher antimicrobial activity in ethanolic extracts. Findings in this study therefore suggest that the active antimicrobial agents in A. vulgaris can be extracted better acetone than with ethanol.

Solvent extraction effects on phytochemical constituents profiles, antioxidant and antimicrobial activities and functional group analysis of Ecballium elaterium seeds and peels fruits

“…For each solvent of seeds extracts, values in the same row followed by a different letter These findings are in accordance with the previous results reporting that acetone is capable to extract antimicrobial compounds from plant materials (Addo-Mensah et al, 2015). The strong antibacterial activity of the extracts against the tested microorganisms was attributed to the presence of high content of polyphenols in seeds and peels fruits extracts.…”

Evaluation of antioxidant, antimicrobial and cytotoxic potential in Artemisia vulgaris L.

“…In general, all fractions showed significant response except HA8 and HA9, as 0% survival of leishmania causing protozoa except fraction HA1 which showed 19% survival was calculated. These results were in agreement with various reports [59].…”

“…However, these results were in agreement with previous work [43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58]. In 2015, Addo-Mensah and coworkers reported significant antibacterial activities of extracts A. vulgaris against Staphylococcus aureus and Bacillus subtilis [59]. In another study it is reported that Artemisia dubia showed antibacterial potential [60].…”

Phytochemistry and pharmacological activity of the genus artemisia

“…The phytochemical assessments of extracts the analysis expressed the presence of flavonoids, terpenoids, phenols, alkaloids, quinines, and tannins (Tajehmiri et al 2014 ; Hiremath et al 2011 ; Parameswari and Devika 2014 ; Addo-Mensah et al 2015 ; Bereksi et al 2018 ; Mamatova et al 2019 ). Despite this, saponins and amino acids were found in methanol and ethanol extracts whereas carbohydrates specifically lie within methanol extracts, and glycosides hydrolyzable tannins were not found in the extracts.…”