Evaluation of antimicrobial efficacy of nanosilver solution, sodium hypochlorite and normal saline in root canal irrigation of primary teeth

Moradi, F; Haghgoo, Roza

doi:10.4103/ccd.ccd_95_18

Cited by 14 publications

(24 citation statements)

References 36 publications

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“…Other studies confirming the effectiveness of nanoparticles against E. faecalis too [107,178]. The level of their effectiveness, however, is slightly lower than that of sodium hypochlorite.…”

Section: Nanoparticle-based Disinfection In Endodonticsmentioning

confidence: 88%

“…Graphene used as a coating on a titanium implant has the potential to improve the properties of osseointegration, accelerate tissue healing, and inhibit microbial growth [106]. It was tested that graphene in combination with silver nanoparticles shows strong antibacterial properties with a lower cytotoxic effect on soft tissues and bones compared to 3% sodium hypochlorite [107]. This makes graphene a promising material for infected canals irrigant in the future.…”

Section: Graphenementioning

confidence: 99%

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Nanomaterials Application in Endodontics

et al. 2021

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In recent years, nanomaterials have become increasingly present in medicine, especially in dentistry. Their characteristics are proving to be very useful in clinical cases. Due to the intense research in the field of biomaterials and nanotechnology, the efficacy and possibilities of dental procedures have immensely expanded over the years. The nano size of materials allows them to exhibit properties not present in their larger-in-scale counterparts. The medical procedures in endodontics are time-consuming and mostly require several visits to be able to achieve the proper result. In this field of dentistry, there are still major issues about the removal of the mostly bacterial infection from the dental root canals. It has been confirmed that nanoparticles are much more efficient than traditional materials and appear to have superior properties when it comes to surface chemistry and bonding. Their unique antibacterial properties are also promising features in every medical procedure, especially in endodontics. High versatility of use of nanomaterials makes them a powerful tool in dental clinics, in a plethora of endodontic procedures, including pulp regeneration, drug delivery, root repair, disinfection, obturation and canal filling. This study focuses on summing up the current knowledge about the utility of nanomaterials in endodontics, their characteristics, advantages, disadvantages, and provides a number of reasons why research in this field should be continued.

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Section: Nanoparticle-based Disinfection In Endodonticsmentioning

confidence: 88%

Section: Graphenementioning

confidence: 99%

Nanomaterials Application in Endodontics

et al. 2021

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“…An in vitro study by Alsamhari et al indicated that 5.25% NaOCl and 2% liquid AgNPs were preferred for the eradication of E. faecalis , S. aureus , Pseudomonas aeruginosa ( P. aeruginosa ), and C. albicans biofilms [ 55 ]. The antimicrobial effect of AgNP solution as an irrigant in treatment of deciduous teeth was examined against monospecies E. faecalis , demonstrating its potential for application as an alternative to other root-canal-irrigating solutions [ 56 ]. A variety of methods are available for preparing AgNPs, including biological, physical, chemical, photochemical, electrochemical, sonolytic, radiolytic, and photochemical processes.…”

Section: Application Of Agnps In Endodonticsmentioning

confidence: 99%

Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review

et al. 2023

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The efficient elimination of microorganisms and their byproducts from infected root canals is compromised by the limitations in conventional root canal disinfection strategies and antimicrobials. Silver nanoparticles (AgNPs) are advantageous for root canal disinfection, mainly due to their wide-spectrum anti-microbial activity. Compared to other commonly used nanoparticulate antibacterials, AgNPs have acceptable antibacterial properties and relatively low cytotoxicity. Owing to their nano-scale, AgNPs penetrate deeper into the complexities of the root canal systems and dentinal tubules, as well as enhancing the antibacterial properties of endodontic irrigants and sealers. AgNPs gradually increase the dentin hardness in endodontically treated teeth and promote antibacterial properties when used as a carrier for intracanal medication. The unique properties of AgNPs make them an ideal additive for different endodontic biomaterials. However, the possible side effects of AgNPs, such as cytotoxicity and tooth discoloration potential, merits further research.

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“…However, it does not affect some bacterial strains such as E. faecalis [ 9 – 11 ]. Infections in the primary root canals are associated with a broad variety of microorganisms, among which E. faecalis is one of the most prevalent and resistant bacteria species in both deciduous and permanent root canals [ 8 , 12 – 14 ].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Efficacy of Intracanal Medicaments against E. Faecalis Bacteria in Infected Primary Molars by Using Real-Time PCR: A Randomized Clinical Trial

Ghahramani

Mohammadi

Gholami

et al. 2020

International Journal of Dentistry

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Aim. This study aimed to compare the antimicrobial efficacy of calcium hydroxide (CH) and triple antibiotic paste (TAP) against E. faecalis bacteria in infected primary molars. Methods and Materials. Thirty-nine 4–6-year-old children with an infected primary molar were randomly divided into three equal groups (n = 13) to receive either CH or TAP and an untreated control group. Following access cavity preparation, the first microbiological samples (S1) were collected by using absorbent paper points. The canals were prepared and rinsed. Then, CH or TAP was applied in the root canals. Seven days later, the second microbiological samples (S2) were collected. DNA extraction was performed to count E. faecalis bacteria by using real-time PCR for S1 and S2 samples. Data were analyzed through one-way ANOVA and Tukey’s test (α = 0.05). Results. E. faecalis bacteria counts decreased significantly in CH and TAP groups compared with the control group ( P ≤ 0.001 ). However, no statistically significant difference existed between these two groups ( P = 0.698 ). Conclusion. Both TAP and CH have significant antimicrobial effects as intracanal medicament between the treatment sessions in infected primary teeth.

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Evaluation of antimicrobial efficacy of nanosilver solution, sodium hypochlorite and normal saline in root canal irrigation of primary teeth

Cited by 14 publications

References 36 publications

Nanomaterials Application in Endodontics

Nanomaterials Application in Endodontics

Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review

Antimicrobial Efficacy of Intracanal Medicaments against E. Faecalis Bacteria in Infected Primary Molars by Using Real-Time PCR: A Randomized Clinical Trial

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