Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts

Roby, Mohamed H. H.; Sarhan, M. A.; Selim, Khaled A.; Khalel, Khalel Ibrahim

doi:10.1016/j.indcrop.2012.08.029

Cited by 497 publications

(369 citation statements)

References 23 publications

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“…The same occurs with results reported by Roby et al (2013) that were expressed in relative percentage of the phenolic compounds identified. Kontogianni et al (2013) described lower concentrations, and this can be noticed in rosmarinic acid levels (10 mg/g of dry extract), which can also be explained by the different solvents used in the extraction procedure (successive extractions with ethyl acetate and hexane).…”

Section: Identification and Quantification Of Phenolic Compoundssupporting

confidence: 88%

“…The presence of both compounds has been reported in leaves and aerial parts of S. officinalis by different authors (Hossain et al, 2010;Cvetkovikj et al, 2013). There are various publications reporting the phenolic composition of S. officinalis from different origins and using different extraction methodologies Wang et al, 1999;Lu & Foo, 2001, 2002Hossain et al, 2010;Zimmermann et al, 2011;Cvetkovikj et al, 2013;Kontogianni et al, 2013;Roby et al, 2013). There are some differences in the phenolic composition described, but some similarities are also observed.…”

Section: Identification and Quantification Of Phenolic Compoundsmentioning

confidence: 90%

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Evaluation of bioactive properties and phenolic compounds in different extracts prepared from Salvia officinalis L.

et al. 2015

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The therapeutic benefits of medicinal plants are well known. Nevertheless, essential oils have been the main focus of antioxidant and antimicrobial studies, remaining scarce the reports with hydrophilic extracts. Thus, the antioxidant and antifungal activities of aqueous (prepared by infusion and decoction) and methanol/water (80:20, v/v) extracts of sage (Salvia officinalis L.) were evaluated and characterized in terms of phenolic compounds. Decoction and methanol/water extract gave the most pronounced antioxidant and antifungal properties, being positively related with their phenolic composition. The highest concentration of phenolic compounds was observed in the decoction, followed by methanol/water extract and infusion. Fungicidal and/or fungi static effects proved to be dependent on the extracts concentration. Overall, the incorporation of sage decoction in the daily diet or its use as a complement for antifungal therapies, could provide considerable benefits, also being an alternative to sage essential oils that can display some toxic effects.

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Section: Identification and Quantification Of Phenolic Compoundssupporting

confidence: 88%

Section: Identification and Quantification Of Phenolic Compoundsmentioning

confidence: 90%

Evaluation of bioactive properties and phenolic compounds in different extracts prepared from Salvia officinalis L.

et al. 2015

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“…As the main components of thyme, triterpenic acids [19] and phenolic compounds [20] were identified similarly as for sage.…”

Section: Salvia Officinalis Salvia Officinalis L (Common Sagementioning

confidence: 99%

“…8 Quantitatively, the most important compounds in thyme are thymol and carvacrol, 9 isoforms of the same monoterpene, which represent almost three-quarters of total volatiles, 10 followed by terpenes, linalool (4%), �-terpineol (2,4%), 1,8-cineole (2,1%), and borneol (2%) 11 [18]. As the main components of thyme, triterpenic acids [19] and phenolic compounds [20] were identified similarly as for sage. 13…”

Section: Salvia Officinalis Salvia Officinalis L (Common Sagementioning

confidence: 99%

“…Roby et al [20] provided evidence that cinnamic acid was the dominant phenolic 14 compound in thyme methanolic extract, since it constituted 28% of the total extracted 15 compounds followed by the two principal flavonoids: apigenin (8%) and luteolin-7-o-rutinose 16 (7%). Protective effect of T. vulgaris essential oil against aflatoxin B1-induced toxicity in rats 17 has been reported by El-Nekeety et al [21].…”

Section: Salvia Officinalis Salvia Officinalis L (Common Sagementioning

confidence: 99%

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Biological effects of four frequently used medicinal plants of Lamiaceae

Srančíková¹,

Horvathova²,

Kozics³

2014

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Cancer is one of the leading causes of death characterized by uncontrolled growth and spread of cancer cells. There are several hundred thousands of new cases of cancer worldwide. Clinical oncology is still challenged by toxicity and side effects of multimodal therapy strategies in which it is associated with poor prognosis for patients. There is an urgent necessity to develop novel therapy strategies and to utilize preventive potential of natural compounds. As the majority of anticancer drugs are of natural origin, natural products represent a valuable source for the identification and development of novel treatment options and chemopreventive mechanisms for cancer. This review is focused on the summary of published knowledges on the antioxidant and potential chemopreventive effects of biologically active substances present in the extracts of four plants of the family Lamiaceae (sage, thyme, rosemary and lavander) in different animal and in vitro systems. It is assumed that the chemopreventive and chemotherapeutic potential of natural compounds is the result of a combined action of several mechanisms.

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