2016
DOI: 10.4314/tjpr.v15i1.19
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Evaluation of Antioxidant and Antifungal Activities of Polyphenol-rich Extracts of Dried Pulp of <i>Garcinia pedunculata</i> Roxb. and <i>Garcinia morella</i> Gaertn. (Clusiaceae)

Abstract: Purpose: To evaluate the antioxidant and antifungal activities of polyphenol-rich extracts of the dried fruit pulp of Garcinia pedunculata (GP) and Garcinia morella (GM) to determine their traditional claims of LPO (IC50= 42 ± 0.01 and 30.36 ± 0.03 μg/mL)

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Cited by 4 publications
(4 citation statements)
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“…In addition, the presence of a number of benzophenones including pedunculol, garcinol, and cambogin and other organic acids, such as citric acid, hydroxycitric acid, hydroxycitric acid lactone, and oxalic acid has also been identified [ 17 , 18 ]. Further insights into GP's efficacy as free radical scavengers and capacity to protect cells from lipid peroxidation have been confirmed in several studies, thus uncovering its medicinal importance related to chronic or degenerative diseases including diabetes [ 9 , 19 ].…”
Section: Introductionmentioning
confidence: 99%
“…In addition, the presence of a number of benzophenones including pedunculol, garcinol, and cambogin and other organic acids, such as citric acid, hydroxycitric acid, hydroxycitric acid lactone, and oxalic acid has also been identified [ 17 , 18 ]. Further insights into GP's efficacy as free radical scavengers and capacity to protect cells from lipid peroxidation have been confirmed in several studies, thus uncovering its medicinal importance related to chronic or degenerative diseases including diabetes [ 9 , 19 ].…”
Section: Introductionmentioning
confidence: 99%
“…typhi (MTCC733), and Vibrio cholera (MTCC 3906), was evaluated and it was found that G. morella methanolic extract exhibited remarkable antibacterial activity against B. cereus (MTCC 430) and S. aureus (MTCC7433) at 200 and 500 µg/mL concentrations. Similarly, Sarma et al [38] demonstrated the antifungal activities of fruit extracts of G. morella against skin pathogenic fungi, namely Trichophyton rubrum, Microsporum gypseum, and Microsporum fulvum (Table 4). Zuo et al [45] investigated the in vitro antimicrobial activities of 80% ethanol extracts of 30 Chinese medicinal plants, including G. morella, against conventional clinical pathogens such as S. aureus (ATCC 25923, methicillin-sensitive Staphylococcus aureus (MSSA)), E. coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), and Candida albicans (ATCC Y0109) by agar diffusion method and calculated the inhibition zone diameters (IZDs).…”
Section: Antimicrobial Propertiesmentioning
confidence: 88%
“…Table 4 summarizes the antioxidant properties of Indian gamboge fruit extracts and garcinol that have been examined. The antioxidant activities of water, acetone, and methanol extracts and that of a chloroform fraction containing garcinol have been demonstrated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity [35][36][37][38], hydrogen peroxide (H 2 O 2 ) scavenging activity [38], the ferric thiocyanate method [35,36,38], and the 2, 2 -azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) assay [37]. The total antioxidant activity (TAC) was demonstrated using the phosphomolybdate assay [36], nitric oxide radical inhibition assay [37], and cyclic voltammetry method [39].…”
Section: Antioxidant Propertiesmentioning
confidence: 99%
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