Evaluation of antioxidant enzyme activity and antioxidant capacity in patients with newly diagnosed pemphigus vulgaris

Javanbakht, Mohammad Hassan; Djalali, Mahmood; Daneshpazhooh, Maryam; Zarei, Mahnaz; Eshraghian, M R; Derakhshanian, Hoda; Chams‐Davatchi, Cheyda

doi:10.1111/ced.12489

Cited by 26 publications

(27 citation statements)

References 22 publications

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“…Similar results were obtained in a study conducted by Javanbakht M among patients of senile cataract and found that the statistically higher prevance of raised serum sodium levels in patients of senile cataract. Most of characteristics of their study were similar to present study (8).…”

Section: Discussionsupporting

confidence: 85%

Comparative Study of Biochemical Parameters Among Elderly Patients With Cataract

Patel

2019

IJMBS

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Background: Cataract is among the most common ocular morbidity seen among elderly patients, it incidence is related to the aging process. It is a ocular morbidity and result in decrease the eye sight. Incidence of cataract related to aging process is generally seen in patients who are aged above 45 years of age. In previous researches it was estimated that approximately seventy five percent of general population above the 70 years of age has reported to suffer from lens opacity or cataract. Material & Methods: Patients who were presenting with nuclear or cortical or posterior sub-capsular cataracts along with healthy age and gender matched controls were enrolled from outdoor and from ward by simple random sampling. Clearance from Institutional Ethics Committee was taken before start of study. Written informed consent was taken from each study participant. Results: On the assessment of serum sodium levels it was found that mean serum sodium levels were 144.12 ± 2.43 meq/l in the cataract group and mean serum sodium levels were 139.37±3.4 meq/l in the age matched controls. This difference among both the groups was statistically significant (P value <0.05). On the assessment of serum potassium levels, it was found that mean serum potassium levels were 4.32 ± 0.11 meq/l in the cataract group and mean serum potassium levels were 4.10 ± 0.16 meq/l in the age matched controls. This difference among both the groups was statistically non-significant (P value >0.05). Conclusion: We concluded from the present study that the higher prevance of raised serum sodium levels in patients of senile cataract. We found that any alteration in serum electrolyte concentration leads to alterations in aqueous humor’s electrolyte concentration and responsible for risk factor for development of senile cataract. Key words: senile cataract, serum sodium, serum potassium.

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Section: Discussionsupporting

confidence: 85%

Comparative Study of Biochemical Parameters Among Elderly Patients With Cataract

Patel

2019

IJMBS

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“…However, CAT destroys H 2 O 2 , generating water and oxygen. It reported that otoimmune disorders like patients with PV have significantly higher antioxidant enzyme activities (25). Our study demonstrated an increase in SOD and CAT activities.…”

Section: Discussionsupporting

confidence: 68%

Oxidative Stress Biomarkers and Adenosine Deaminase over the Alopecic Area of the Patients with Alopecia Areata

Öztürk¹,

Arıcan²,

Kurutaş³

et al. 2016

Balkan Med J

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“…She also received instructions on increasing antioxidant food as fruits, emphasizing the exclusion of foods such as: garlic, onions, cherries, blackberries, black pepper, red wine, tea, coffee, because they have a direct influence on the development of the disease. 8 In the first assessment, the patient presented weight (94,5Kg decreasing to 88.7 (BMI for overweight) at reassessment; height (1.64 m), with Body Mass Index (BMI) indicating a grade II obesity (BMI=35.13 kg/m²) initially, high WC (107.5cm) and 97 cm after, HP (122 cm) going to 116.5, AC indicating obesity (35.05 cm), subsequently 33cm (overweight) and waist-hip ratio (WHR) (0.88 cm), decreasing to 0.83, indicating, in both assessments, high risk for cardiovascular diseases (Table 01). In the evaluation of the InBody Bioimpedance, her results improved, with values on the body composition with weight reduction preserving the skeletal muscle mass and reducing fat mass (Graph 01).…”

Section: Description Of the Case And Resultsmentioning

confidence: 99%

“…By analyzing her food routine, the research subject had relevant changes in her habits, such as greater consumption of antioxidants, which was very important, since she demonstrated the need to improve the level of antioxidants. 8 A study showed that 43 patients newly diagnosed with PV presented activities of antioxidant enzymes significantly higher and lower total antioxidant capacity.…”

Section: Discussionmentioning

confidence: 99%

Intervenção Dietoterápica No Tratamento De Pênfigo Vulgar: Relato De Caso

Santos¹,

Sobreira²,

Santos³

et al. 2019

Revista E-Ciência

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Vulgar é uma patologia autoimune, sucede em ambos os sexos afetando principalmente pessoas na quarta e na sexta década de vida. Manifesta-se pela produção de anticorpos contra as desmogleínas, acometendo pele e mucosa. O objetivo deste estudo foi verificar o resultado da intervenção dietoterápica no tratamento do Pênfigo Vulgar (PV), sendo este um estudo de caso do tipo descritivo, exploratório, de abordagem qualitativa, na cidade de Juazeiro do Norte. Foi realizado com uma mulher, adulta, diagnosticada com PV onde foi realizado duas avaliações, uma anterior a intervenção dietoterápica e outra após, afim de analisar seu efeito. A paciente apresentou diminuição de 5,8Kg de peso e 10,5 cm de cintura, influenciando diretamente no seu IMC que passou de 35,13 Kg/m² (obesidade grau III) para 32,97Kg/m² (obesidade grau II), sem perda significativa de massa muscular nesse processo de emagrecimento e diminuição dos sintomas decorrentes do PV. Com a intervenção dietoterápica foi percebido que alimentação tem influência direta, positiva e negativa sobre o Pênfigo Vulgar, como também no tratamento e prevenção de comorbidades associadas. O que faz necessária a presença de profissionais multidisciplinares capacitados para tratar pessoas com PV, em especial a inclusão do nutricionista. Ressalta-se a importância de mais estudos envolvendo a influência da alimentação no tratamento e desenvolvimento do Pênfigo Vulgar.

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Evaluation of antioxidant enzyme activity and antioxidant capacity in patients with newly diagnosed pemphigus vulgaris

Abstract: Patients with PV have significantly higher antioxidant enzyme activities and lower total antioxidant capacity compared with HCs. These data indicate the importance of improving antioxidant level in patients with pemphigus.

Cited by 26 publications

References 22 publications

Comparative Study of Biochemical Parameters Among Elderly Patients With Cataract

Comparative Study of Biochemical Parameters Among Elderly Patients With Cataract

Oxidative Stress Biomarkers and Adenosine Deaminase over the Alopecic Area of the Patients with Alopecia Areata

Intervenção Dietoterápica No Tratamento De Pênfigo Vulgar: Relato De Caso

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