Evaluation of Bone Mineral Density in Patients With Spinal Cord Injury

Kaya, Kurtuluş; Aybay, Canan; Özel, Sumru; Kutay, Nilufer; Gokkaya, Ordu

doi:10.1080/10790268.2006.11753888

Cited by 27 publications

(12 citation statements)

References 17 publications

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“…Kaya et al 34 in their study on SCI patients correlated serum P and Alk-ph along with 24 h urine Ca levels and urine Ca to Cr ratio to the condition. They, however, reported the value to be higher in patients with a longer history of the lesion.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and associated factors of T-score discordance between different sites in Iranian patients with spinal cord injury

et al. 2013

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Objectives: The present study was conducted to determine the prevalence of T-score discordance and its risk factors in a group of patients with spinal cord injury in a university teaching hospital in the Iranian capital of Tehran. Methods: This cross-sectional study was conducted on paraplegic men undergoing bone density testing in an outpatient clinic at a hospital in the Iranian capital, Tehran, between March 2011 and 2012. A questionnaire on demographic and anthropometric characteristics, including age, height, weight, engagement in physical activity and personal smoking habits, was filled out for each subject. All the subjects underwent bone mineral density measurement and blood samples were sent for laboratory testing. Results: Major T-score discordance between two sites was noted in 54 (41.22%) patients. Multivariate logistic regression revealed that every unit increase in serum calcium levels, as the only factor influencing T-score discordance, was associated with a 2.49-fold increased risk in T-score discordance in the area. As for the spine and radius, BMI was the only influencing factor as every unit increase in BMI was associated with a 14% lower risk for T-score discordance in these regions. Body mass index was the only factor, based on the multivariate model, affecting the risk of developing T-score discordance between two sites. Conclusion: Our study revealed the high prevalence of T-score discordance in patients with spinal cord injury. Physicians should therefore be encouraged to perform BMD at three sites when visiting patients with such injuries.

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Section: Discussionmentioning

confidence: 99%

Prevalence and associated factors of T-score discordance between different sites in Iranian patients with spinal cord injury

et al. 2013

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“…O DEXA é um instrumento utilizado para mensurar a CC regional (tronco, pernas, braços, região andróide e ginóide) e geral de massa livre de gordura, massa de gordura (SPUNGEN et al, 2003;MODLESKY et al, 2004;MANNS;McCUBBIN;WILLIAMS, 2005;HALSTEAD et al, 2010;GORGEY et al, 2010a;DOLBOW et al, 2012) e na análise corporal regional e de densidade mineral óssea (SPUNGEN et al, 2003;KAYA et al, 2006;YILMAZ et al, 2007;MORSE et al, 2009).…”

Section: Dexa -Dual Energy X-ray Absorptiometryunclassified

“…O uso do DEXA para análise da CC em pessoas com lesão medular é, sem dúvida, o mais comumente utilizado nos estudos encontrados, principalmente no exterior (JONES; LEGGE; GOULDING, 2003;SPUNGEN et al, 2003;MODLESKY et al, 2004;GATER, 2005;MANNS;MCCUBBIN;WILLIAMNS;KAYA et al, 2006;YILMAZ et al, 2007;EDWARDS et al, 2008;FORREST et al, 2008;MARUYAMA et al, 2008;GRIFFIN et al, 2009;MORSE et al, 2009;GORGEY et al, 2010a;HALSTEAD et al, 2010;CRANE et al, 2011;RIBEIRO et al, 2011;DOLBOW et al, 2012;AÑÓ et al, 2012;KOURY et al, 2013). O uso frequente do DEXA neste tipo de análise justifica-se por ter se mostrado um instrumento eficiente capaz de identificar indivíduos com percentagens de gordura corporal consistentes com a obesidade, quando parâmetros como medições de prega cutânea e análise por bioimpedância, e indiretos, como o IMC, classificam o indivíduo com estado nutricional normal (limítrofe) (CRANE et al, 2011).…”

Section: Dexa -Dual Energy X-ray Absorptiometryunclassified

“…No estudo de Kaya et al (2006) somente o uso do DEXA não determinou a perda precoce de mineral ósseo, o qual também foi analisado por meio de marcadores bioquímicos. Ainda, deve-se apontar que pequenas alterações na angulação óssea (posição do indivíduo no momento da análise) por ocasião da análise pré e pós-intervenção podem causar variabilidade entre as medições (GRIFFIN et al, 2009) O uso exclusivo do DEXA como método para mensurar a CC regional pode não refletir precisamente o valor real.…”

Section: Dexa -Dual Energy X-ray Absorptiometryunclassified

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Métodos de avaliação da composição corporal de adultos com lesão medular: uma revisão

Vargas

Oliveira

Vargas

et al. 2017

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ResumoEste estudo tem como objetivo realizar uma revisão na literatura acerca dos métodos de avaliação da composição corporal (CC) de indivíduos acometidos de lesão medular completa. Foram realizadas buscas em artigos publicados entre 2002 e 2013 que envolvessem pesquisas exploratórias (longitudinais ou transversais). Foi realizada uma revisão sistemática nas bases eletrônicas de dados multidisciplinares -Web of Science e Scopus, que integram as bases eletrônicas: Medline, Pubmed, Lilacs, Portal Scielo, SciVerse e Bireme. Os descritores pesquisados foram construídos com base na estratégia P.I.C.O. e relacionaram-se com as seguintes palavras: lesão na medula espinhal, quadriplegia ou tetraplegia, paraplegia e composição corporal (em português e inglês). Foram encontrados um total de 108 artigos. Desses, 30 artigos foram classificados como exploratórios e se enquadraram nos critérios de inclusão. Dentro dessa magnitude de métodos e instrumentos capazes de avaliar a CC de indivíduos com lesão medular, podese concluir que: os profissionais da área da saúde que utilizam métodos de avaliação da CC o fazem para obterem estratégias e/ou intervenções mais adequadas para essa população; os mesmos estão atentos as especificidades dos instrumentos/equipamentos que permitem a avaliação direta da CC e os possíveis equívocos ligados a estimação de componentes corporais de indivíduos com lesão medular; ademais, conhecem a fidedignidade dos resultados das avaliações antropométricas. Alguns estudos indicam que Grupo de Pesquisa em Avaliação da qualidade de vida e qualidade de vida no trabalho Ponta Grossa -PR -Brasil v. 02, n. 02, jul./dez. 2017, p. 39-56

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“…12 In view of these facts, bone fragility and fracture risk appear to arise during the early stage in younger patients with SCI. Moreover, as the duration of SCI is prolonged, the hip BMD value decreases, 13 and consequently the fracture risk of hip bone may rise. Therefore, special intervention for preventing fracture should be performed as soon as possible after injury.…”

Section: Osteoporosis Is a Well-known Complication Of Spinal Cord Injmentioning

confidence: 99%

Whole-body vibration can attenuate the deterioration of bone mass and trabecular bone microstructure in rats with spinal cord injury

et al. 2015

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Study design: Experimental, controlled study. Objective: To examine the effects of whole-body vibration (WBV) on bone mass and trabecular bone microstructure (TBMS) during the early stage in juvenile rats with spinal cord injury (SCI). Setting: Studied at the Kio University in Japan. Methods: Thirty-four 8-week-old male Wistar rats were divided into 3 groups: the SCI group, the sham-operation group (SHAM) and the SCI+WBV group. WBV started on the 8th day after SCI. After 1 or 2 weeks of WBV treatment, measurements of tissue mineral density, trabecular bone mineral content (BMC) and parameters of TBMS were obtained by scanning the proximal tibias with x-ray micro-computed tomography. Serum levels of osteocalcin (OC) and of tartrate-resistant acid phosphatase 5b (TRACP 5b) were measured with ELISA. Results: BMC, volume bone mineral density, bone volume (BV), BV fraction (BV/tissue volume) and connectivity density (Conn.D) of TBMS parameters were significantly higher in SCI+WBV rats than in SCI rats after 2-week WBV. The BMC and BV/TV of bone mass index correlated well with Conn.D, suggesting the preservation of Conn.D. induced by WBV. SCI+WBV rats showed a decrease in serum OC after 1-week WBV, but a quick recovery from that after 2-week WBV. There was no difference in serum TRACP 5b among the 3 groups throughout the experimental period. Conclusion: WBV treatment could attenuate the bone deterioration that occurs during the early stage in juvenile rats with SCI. In a clinic, this early WBV intervention may be an effective rehabilitation modality for preventing bone fragility in SCI patients. Spinal Cord (2016) 54, 597-603; doi:10.1038/sc.2015.220; published online 22 December 2015 INTRODUCTION Osteoporosis is a well-known complication of spinal cord injury (SCI).The mechanism of bone loss by SCI is complex and is constituted by multiple factors involving mechanical, neurovascular, hormonal and metabolic factors. 1,2 Bone loss following SCI begins within the first 6 months after the injury, and stabilizes between 12 and 16 months. 3 Bone loss is especially prominent in sublesional bones such as the distal femur and proximal tibia. [4][5][6][7][8] In fact, bone mass in the distal femur and proximal tibia decreased by 51% and 70%, respectively, within 1 year after the injury in SCI patients. 6 These two bones were so fragile that even a weak physical impact could cause a fracture in SCI patients. 7,8 Therefore, the frequency of fracture in SCI patients was about twice as high as that of healthy people. 9 Edwards et al. 10 showed that in the femur and tibia of acute SCI patients trabecular bone mineral content (BMC) was reduced by 3.1-4.4% per month and volumetric bone mineral density (BMD) by 2.7-4.7% per month within 4 months after the injury. In addition, cortical BMC and volumetric BMD were noticeably reduced, and furthermore bone strength indices were decreased. 10 The incidence of SCI is higher in young people aged 15-24 years. 11 Children (aged 5-13 years) with

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Evaluation of Bone Mineral Density in Patients With Spinal Cord Injury

Cited by 27 publications

References 17 publications

Prevalence and associated factors of T-score discordance between different sites in Iranian patients with spinal cord injury

Prevalence and associated factors of T-score discordance between different sites in Iranian patients with spinal cord injury

Métodos de avaliação da composição corporal de adultos com lesão medular: uma revisão

Whole-body vibration can attenuate the deterioration of bone mass and trabecular bone microstructure in rats with spinal cord injury

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