A large share of the Danish building stock contains historic multi-storey buildings. A considerable energy saving potential exists, achievable through thermal insulation of the façades. Previous research has elucidated problems regarding poor hygrothermal conditions when interior thermal insulation is applied to the façade, but examples exist with positive results. Eight 1x2 m solid masonry test walls with wooden members were installed in an insulated container. The hygrothermal implication of applying 100 mm AAC as interior thermal insulation system was investigated with variations including use of hydrophobation and substitution of insulating material with a deliberate thermal bridge. Highlights • Conditions behind thermal insulation reached critical values for mould growth. • Conditions can be altered by hydrophobation and deliberate thermal bridges. • Hydrophobation reduced relative humidity in summer, with rapid increase in winter. • Relative humidity in built-in wood can be reduced by incorporating thermal bridge. • Example of fit between wind driven rain model and measurements.