Evaluation of Changes in Haematological Profile of Cerebral Malaria Patients in Enugu State, Southeast, Nigeria

Obeagu, Emmanuel Ifeanyi; Didia, BC; Obeagu, Getrude Uzoma; Azuonwu, O

doi:10.21767/2386-5180.1000202

Cited by 10 publications

(15 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Immune complexes generated by malarial antigens lead to sequestration of the injured platelets by macrophages in the spleen. Also, platelet consumption in disseminated intravascular coagulation is thought to contribute to thrombocytopenia in malaria [7,[18][19][20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Age-Related Haematological Variations in Patients with Asymptomatic Malaria in Akure, Ondo State, Nigeria

Obeagu

Busari

Uduchi

et al. 2021

JPRI

View full text Add to dashboard Cite

Background: Malaria is a life-threatening infectious disease of widespread burden. Malaria remains a leading communicable disease in the developing countries of the world. It occurs mostly in the tropical and subtropical regions and accounts for considerable morbidity and death. Malaria which is liable for a major amount of mortalities in endemic countries has been revealed to have both direct and indirect impacts on the haematologicalparameters.The study was done to compare the levels of haematological parameters of asymptomatic malaria patients based on age groups. Methods: The study is a cross-sectional study among asymptomatic malaria patients based on age groups. This study was conducted in Oda Road area of Akure, Ondo State. Two hundred (200) subjects were recruited for this study with each group comprising of 100 subjects for patients with asymptomatic malaria for the 2 age groups (16-30 years and 31-65 years). The data were presented in tables and as mean ± standard deviation and analyzed using student-test for parametric data and chi-square for non parametric data by statistical packages for social sciences (SPSS, Version 20.0) and level of significance set at as p≤ 0.05. Results: The results showed that subjects on age group 16-30 years were 100(50%) comprising of 50 males (25%) and 50 females (25). Also age group 31-65 years has 100 subjects (50%) comprising of 50 males (25%) and 50 females (25).The results showed significant difference in MCV (p=0.008), MCH (p=0.024) and no significant difference in PCV (p=0.675), WBC (p= 0.224), LYM (p=0.109), GRAN (p=0.061), MID (p=0.066), RBC (p=0.119), Hb (p=0.546), MCHC (p=0.262), PLT (p=0.783), when compared between age groups in years (16-30 and 31-65). Conclusion: The study showed increase in MCV and MCH of asymptomatic malaria patients within the age group of 31-65 years compared to asymptomatic malaria patients on 16-30 years age group. This shows that microcytic hypochromic anaemia may be experienced in asymptomatic malaria patients within the age group of 16-30 years more than in 31-65 years age group.

show abstract

Section: Discussionmentioning

confidence: 99%

Age-Related Haematological Variations in Patients with Asymptomatic Malaria in Akure, Ondo State, Nigeria

Obeagu

Busari

Uduchi

et al. 2021

JPRI

View full text Add to dashboard Cite

show abstract

“…Further, majority (80.0%) responded that women's knowledge affect uptake of fansider. Although ANC coverage is generally high in African nations, many nations have struggled to attain high levels of IPTp adoption [26,27,28,29]. It implies that there are unutilized opportunities to provide IPTp during ANC.…”

Section: Challenges Faced In Administration Of Sulfadoxine-pyremethaminementioning

confidence: 99%

Enhancing IPTp Program Implementation: Provider Practices, Challenges, and Malaria Prevalence among Pregnant Women in Uganda

Kanobere

2024

IDOSR-JST

View full text Add to dashboard Cite

Malaria remains a formidable public health threat, particularly in sub-Saharan Africa, where pregnant women face heightened vulnerability. Intermittent Preventive Treatment in pregnancy with Sulfadoxine Pyrimethamine (IPTp-SP) stands as a pivotal strategy in malaria prevention efforts. However, its full potential is hindered by challenges in implementation. This study, conducted at Bushenyi Health Centre IV in Uganda, scrutinized provider practices, challenges encountered, and malaria prevalence among pregnant women attending antenatal care services. Through a descriptive cross-sectional approach involving 151 pregnant mothers and 15 antenatal care providers, analysis revealed noteworthy insights. While a majority of pregnant women received IPTp-SP, adherence to WHO guidelines regarding administration timing and frequency was suboptimal. Notably, over half of the providers reported stockouts of IPTp-SP, leading to significant delays in replenishment and impeding service delivery. Moreover, providers identified a crucial link between women's knowledge and IPTp uptake. The study also uncovered a malaria prevalence of 7.9% among pregnant women. These findings underscore the urgent need to address implementation challenges, particularly in supply chain management and health education, to fortify malaria prevention strategies for pregnant women in Uganda. Keywords: Malaria, Pregnant women, IPTp-SP, Antenatal care, Implementation challenges, Supply chain management, Health education, Uganda.

show abstract

“…However, P. falciparum remains the single most serious hazard to global public health because it is the deadliest [9]. It is responsible for more than 90% of malaria deaths worldwide [10]. Early Malaria detection and treatment decrease sickness, avoid fatalities and can help minimize malaria transmission.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology and Clinical Profile of Complicated Malaria in Children under 5 Years at Kiryandongo General Hospital, Uganda

Joel

2024

IDOSR-JBBAF

View full text Add to dashboard Cite

Malaria remains a significant public health concern, especially in sub-Saharan Africa, where children under the age of five are disproportionately affected. This study aimed to investigate the prevalence and clinical profile of complicated malaria among children under five years at Kiryandongo General Hospital in Uganda. Data were collected through an interviewer-administered questionnaire from 192 children admitted with malaria. Results showed that 37.5% of children had complicated malaria, with the highest prevalence observed in the 2-3 years age group (25%). Males were more affected (61%), and convulsions, hyperparasitemia, and hypoglycemia were common symptoms, particularly among children aged two to three years. These findings underscore the urgent need for targeted interventions and improved healthcare resources to combat malaria, especially in vulnerable populations such as young children in endemic regions. Keywords: Malaria, Complicated Malaria, Children, Prevalence, Clinical Profile, Kiryandongo General Hospital, Uganda.

show abstract

Evaluation of Changes in Haematological Profile of Cerebral Malaria Patients in Enugu State, Southeast, Nigeria

Cited by 10 publications

References 5 publications

Age-Related Haematological Variations in Patients with Asymptomatic Malaria in Akure, Ondo State, Nigeria

Age-Related Haematological Variations in Patients with Asymptomatic Malaria in Akure, Ondo State, Nigeria

Enhancing IPTp Program Implementation: Provider Practices, Challenges, and Malaria Prevalence among Pregnant Women in Uganda

Epidemiology and Clinical Profile of Complicated Malaria in Children under 5 Years at Kiryandongo General Hospital, Uganda

Contact Info

Product

Resources

About