Evaluation of chlorprophenpyridamine for prevention of postpartum breast engorgement

Stenchever, Morton A.

doi:10.1016/0002-9378(62)90076-5

Cited by 8 publications

(6 citation statements)

References 17 publications

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“…Among women using a brassiere or binder, ice packs, or analgesics, moderate and severe milk leakage was reported in 22% to 48% and 17% to 40% of women, respectively. 14,15,20 Moderate breast engorgement was reported in 21% to 52% of women 14,15,17,18,20 and severe engorgement was reported in 1% to 44% of women. 7,11,14,15,18,20 Moderate pain was reported in 29% to 68% of women, 7,14-20 and severe pain was reported in 10% to 33% of women.…”

Section: Resultsmentioning

confidence: 99%

“…14,15,20 Moderate breast engorgement was reported in 21% to 52% of women 14,15,17,18,20 and severe engorgement was reported in 1% to 44% of women. 7,11,14,15,18,20 Moderate pain was reported in 29% to 68% of women, 7,14-20 and severe pain was reported in 10% to 33% of women. 11,[14][15][16]20 In only 1 study 7 was the proportion of women using analgesics for pain reported (42%).…”

Section: Resultsmentioning

confidence: 99%

“…Fourteen studies met these criteria. [8][9][10][11][12][13][14][15][16][17][18][19][20][21] We also included a study of pharmacologic and nonpharmacologic methods of lactation suppression that met these criteria. 7 For each of the 15 studies we extracted data on the percentages of women experiencing moderate or severe milk leakage, breast engorgement, and pain and the percentage of women using analgesics for postpartum breast pain.…”

Section: Methodsmentioning

confidence: 99%

“…†Recommended management before 1905 included covering breasts with belladonna ointment, bandaging of breasts tightly, pumping "excess" milk from breasts after they became very engorged and painful, and repeating the process as frequently as necessary. 5 brassiere or binder to suppress lactation 7, 14-20 ; of these, 4 included women who were also instructed to use ice packs, [14][15][16]18 and 7 included women who were also advised to use analgesics for pain. 7,[14][15][16][18][19][20] For the 8 studies we extracted data on the percentages of women in the placebo group who, despite using a brassiere or binder, ice packs, or analgesics, experienced moderate or severe milk leakage, breast engorgement, and pain and the percentage of women who used analgesics for postpartum breast pain.…”

Section: Methodsmentioning

confidence: 99%

“…Moderate 22%-49% 14,15,20 21%-66% 9, 10, 13-15, 17, 18, 20 29%-68% 10,[12][13][14][15][16][17]19,20 Severe 17%-47% 8,11,14,15,20 1%-56% 7,8,11,14,15,18,20 10% to 49% 8, 10-12, 14-16, 20 Variability in definitions Moderate Mild to moderate 15 Tender and congested, 9 Moderate or severe, 13 mild to firm, 10,17,18 mild to moderate, 15 tender or tender moderate, 15 or to palpation, 17 painful lactation 19 moderate or severe 13 Severe Hard, painful, reddened 7 or rock hard 18 *Includes studies of women who were instructed to use a brassiere or binder to suppress lactation 7, 14-20 ; of these, 4 studies included women who were also instructed to use ice packs [14][15][16]18 and 7 included women who were also advised to use analgesics for pain. 7,[14][15][16][18][19]…”

Section: Degree Of Severitymentioning

confidence: 99%

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Treatment for lactation suppression: Little progress in one hundred years

Spitz¹,

Lee²,

Peterson³

1998

American Journal of Obstetrics and Gynecology

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Our goal was to characterize the postpartum symptoms experienced by women who do not breast-feed and to review data on the efficacy of nonpharmacologic methods of lactation suppression. The placebo arms of randomized clinical trials of pharmacologic methods for lactation suppression were used to characterize postpartum symptoms. A subset of the placebo arms was reviewed to assess current strategies for treatment of symptoms associated with lactation suppression. Studies of nonpharmacologic methods of lactation suppression were also reviewed to assess efficacy. Engorgement and breast pain may encompass most of the first postpartum week. Up to one third of women who do not breast-feed and who use a brassiere or binder, ice packs, or analgesics may experience severe breast pain. Specific studies of nonpharmacologic methods of lactation suppression were limited and inconclusive. Available data suggest that many women using currently recommended strategies for treatment of symptoms may nevertheless experience engorgement or pain for most of the first postpartum week.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Degree Of Severitymentioning

confidence: 99%

See 3 more Smart Citations

Treatment for lactation suppression: Little progress in one hundred years

Spitz¹,

Lee²,

Peterson³

1998

American Journal of Obstetrics and Gynecology

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Treatments for breast engorgement during lactation

Snowden

Renfrew

Woolridge

2001

Cochrane Database of Systematic Reviews

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Cabbage leaves and gel packs were equally effective in the treatment of engorgement. Since both cabbage extract and placebo cream were equally effective, the alleviation in symptoms may be brought about by other factors, such as breast massage. Ultrasound treatment is equally effective with or without the ultra-wave emitting crystal, therefore its effectiveness is more likely to be due to the effect of radiant heat or massage. Pharmacologically, oxytocin was not an effective engorgement treatment while Danzen and bromelain/trypsin complex significantly improved the symptoms of engorgement. Initial prevention of breast engorgement should remain the key priority.

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