Evaluation of choroidal tumors with optical coherence tomography: enhanced depth imaging and OCT-angiography features

Abstract

AimTo describe the vascular features of choroidal tumors using enhanced depth imaging (EDI), optical coherence tomography (OCT), and OCT-angiography.MethodsIn this prospective study, we evaluated 116 Caucasian patients with choroidal tumors (60 eyes with choroidal nevi, 40 with choroidal melanoma, 6 with choroidal hemangioma, 2 with optic disc melanocytoma, 6 with choroidal osteoma, and 2 with retinal metastases). Patients underwent a complete ophthalmic examination including bulbar echography, EDI-OCT, OCT-angiography, and multicolor imaging. Sixteen patients also underwent fluorescein and indocyanine angiography.ResultsThe left eye was more involved than the right eye. The mean tumor thickness was 1.23±0.17 mm in the 60 eyes with choroidal nevi; 2.75±0.83 mm in the 40 eyes with choroidal melanoma; 3.28±0.78 mm in the 6 eyes with retinal angioma; 2.02±0.001 mm in the 2 eyes with optic disc melanocytoma; 2.40±0.31 mm in the 6 eyes with choroidal osteoma; and last, 3.49±0.001 mm in the 2 eyes with retinal metastases. OCT-angiography showed: (i) a lack of blood flow in the outer retinal layer (ORL) and a normal choroid capillary layer in choroidal nevi and optic disc melanocytomas; (ii) a lack of blood flow in the ORL of choroidal metastases; and (iii) a dense irregular vascular network in the ORL and choroid capillary layers of choroidal melanomas, choroidal hemangiomas, and choroidal osteomas.ConclusionsOCT-angiography is a noninvasive reliable method with which to evaluate the vascularization of small choroidal tumors and may improve the diagnosis of these tumors.

Evaluation of Vascular Changes with Optical Coherence Tomography Angiography after Plaque Radiotherapy of Choroidal Melanoma

“…The introduction of optical coherence tomography angiography (OCT-A) into the clinical practice allows the detection and visualization of blood flow and morphology of retinal vessels [9]. Very recently, we have demonstrated that OCT-A is a reliable, noninvasive procedure with which to evaluate the vascularization of small choroidal tumors [10]. The aim of the present study was to evaluate whether OCT-A can be used to quantify the extent of vascular changes in radiation maculopathy, and changes in the tumor vasculature in eyes treated with plaque radiotherapy for choroidal melanoma.…”

Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma

“…Enhanced depth imaging (EDI)-OCT showed CCH as a lesion with a smooth, sloping anterior surface without choriocapillaris compression [12,14]. Other authors described CCH in EDI-OCT images as a medium-to-low reflective band with a homogeneous signal and intrinsic spaces that possibly correspond to vascular spaces [15,16].…”

Choroidal Alterations of Sturge-weber Syndrome Secondary Glaucoma and Non-glaucoma Port-wine Stain Patients Distinguished by Enhanced Depth Imaging Optical Coherence Tomography

“…De nition of choroidal hemangioma (both criteria had to be met): EDI-OCT showed elevation of the retina/choroid complex with a low-to-medium re ective signal from the lesion (14) and indirect ophthalmoscope and color fundus photography showed an orange elevated tumor (15) or a difference in color of the fundus between fellow eyes. (13) ( Fig.…”