2006
DOI: 10.1097/01.pcc.0000224993.03233.63
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Evaluation of clinical criteria for the acute respiratory distress syndrome in pediatric patients*

Abstract: Our study suggests the need for further research with larger number of children to identify an optimal Pao2/Fio2 threshold for identifying ARDS in this population.

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Cited by 21 publications
(14 citation statements)
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“…[14][15][16] Specific modifications to the definition of ALI and ARDS have been made to account for the documented changes in gas exchange efficiency that develop in neonatal foals (< 7 days old) as well as in infants. 15,25 In the consensus definitions of ALI and ARDS in veterinary medicine, the threshold of equine neonatal ALI is defined as a Pao 2 :Fio 2 ratio of < 250 mm Hg, whereas equine neonatal ARDS is defined as a Pao 2 :Fio 2 ratio of < 160 mm Hg at 4 days after birth. 15 The Pao 2 :Fio 2 ratio that was considered normal in that report 15 was a value > 400 mm Hg.…”
Section: Discussionmentioning
confidence: 99%
“…[14][15][16] Specific modifications to the definition of ALI and ARDS have been made to account for the documented changes in gas exchange efficiency that develop in neonatal foals (< 7 days old) as well as in infants. 15,25 In the consensus definitions of ALI and ARDS in veterinary medicine, the threshold of equine neonatal ALI is defined as a Pao 2 :Fio 2 ratio of < 250 mm Hg, whereas equine neonatal ARDS is defined as a Pao 2 :Fio 2 ratio of < 160 mm Hg at 4 days after birth. 15 The Pao 2 :Fio 2 ratio that was considered normal in that report 15 was a value > 400 mm Hg.…”
Section: Discussionmentioning
confidence: 99%
“…Various indexes of oxygen exchange are used to guide mechanical ventilatory support [23] and are used also as prognostic indicators, although their reliability is not universally accepted [24]. At present there are no studies on EVLWi as prognostic indicator in pediatrics.…”
Section: Introductionmentioning
confidence: 99%
“…In children, direct pulmonary insult such as pneumonia is the main cause of acute lung injury and ARDS cases. 36 Experimental work support that tissue ACE activity could be more important than circulating levels in acute lung injury pathogenesis. 37 High levels of pulmonary AT-II may potentially impair gas exchange by promoting arteriolar hypoxic vasoconstriction and increasing vascular permeability leading to pulmonary edema.…”
Section: Discussionmentioning
confidence: 99%