Evaluation of Clove and Ginger-mediated Titanium Oxide Nanoparticles-based Dental Varnish against Streptococcus mutans and Lactobacillus Species: An In Vitro Study

Chokkattu, Jerry Joe; Mary, Ditty J; Shanmugam, Rajeshkumar; Neeharika, Singamsetty

doi:10.5005/jp-journals-10015-2185

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…Significant growth inhibition was seen at 100 μL as compared to 25 and 50 μL in the statistical analysis for MBC performed on all test samples of all concentrations against S. mutans and Lactobacilli sp . [ 17 ]…”

Section: Discussionmentioning

confidence: 99%

Biosynthesis of Cissus rotundifolia Stem-Mediated Titanium Dioxide Nanoparticles and Their Anticariogenic Activity against Streptococcus mutans and Lactobacillus sp.

Rajasekar,

Shanmugam,

Anandan

2024

Journal of Pharmacy and Bioallied Sciences

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Introduction: The green synthesis of metal oxide nanoparticles using plant extracts has emerged as an eco-friendly method. Titanium dioxide nanoparticles (TiO2NPs) were synthesized using Cissus rotundifolia in this study. Titanium dioxide nanoparticles were utilized in restorative medicine for enhanced medicinal properties and in dental composites for their antimicrobial activities. Cissus rotundifolia is recognized as a medicinal plant due to its diverse properties, including mild laxatives, anti-inflammatory, and hyperglycemic activities. Materials and Methods: The antimicrobial activity of the prepared nanoparticles against Lactobacillus Sp. and Streptococcus mutans was evaluated using agar well diffusion method. The bactericidal and bacteriostatic activity of the prepared TiO2NPs was examined using time-kill kinetic analysis. Results: The prepared nanoparticles exhibited potential antimicrobial activity against Lactobacillus sp. (12 mm) at the highest concentration of 100 µg/mL. The prepared nanoparticles also exhibited excellent bactericidal activity against Lactobacillus Sp. and mild bacteriostatic activity against Staphylococcus mutans at the highest concentration of 100 µg/mL. Conclusion: The synthesized TiO2NPs showed significant antimicrobial activity against dental pathogens. The observed anticariogenic activity shows the potential of nanoparticles for dental applications. Hence, the prepared nanoparticles can be used in the field of dentistry as an antimicrobial agent instead of synthetic drugs causing more side effects.

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Section: Discussionmentioning

confidence: 99%

Biosynthesis of Cissus rotundifolia Stem-Mediated Titanium Dioxide Nanoparticles and Their Anticariogenic Activity against Streptococcus mutans and Lactobacillus sp.

Rajasekar,

Shanmugam,

Anandan

2024

Journal of Pharmacy and Bioallied Sciences

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“…Advances in nanotechnology are deeply intertwined with other technologies, many of which have received far greater attention. Copper has long been known for its antibacterial and anti-inflammatory effects [ 24 ]. The cost-effectiveness of the copper nanoparticles makes them a viable substitute for gold and silver nanoparticles.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of copper oxide nanoparticles using Piper longum and Piper betle

Selvaganesh

2023

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It is of interest to evaluate the antibacterial, anti-inflammatory, and antioxidant effects of copper nanoparticles synthesized using Piper longum and Piper betle. The copper nanoparticles were characterized using various techniques and found to have a diameter between 30 and 90 nm. The nanoparticles exhibited significant antibacterial activity against E. faecalis, S. aureus, C. albicans, and S. Mutans, comparable to gold standards. They also demonstrated anti-inflammatory effects similar to the gold standard values. Furthermore, the copper nanoparticles displayed antioxidant capabilities, with maximum inhibition of 85.16% at 50 g/ml and a minimum inhibition of 50.62% at 10 g/ml. Overall, the study suggests that Piper longum and Piper betle mediated copper nanoparticles possess promising antibacterial, anti-inflammatory, and antioxidant properties, indicating their potential use in various applications.

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Embryonic Toxicology Evaluation of Dental Varnish Using Titanium Oxide Nanoparticles Synthesized Using Ginger and Rosemary

Ramakrishnan,

Shanmugam,

Neeharika

et al. 2023

World Journal of Dentistry

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Evaluation of Clove and Ginger-mediated Titanium Oxide Nanoparticles-based Dental Varnish against Streptococcus mutans and Lactobacillus Species: An In Vitro Study

Cited by 3 publications

References 33 publications

Biosynthesis of Cissus rotundifolia Stem-Mediated Titanium Dioxide Nanoparticles and Their Anticariogenic Activity against Streptococcus mutans and Lactobacillus sp.

Biosynthesis of Cissus rotundifolia Stem-Mediated Titanium Dioxide Nanoparticles and Their Anticariogenic Activity against Streptococcus mutans and Lactobacillus sp.

Efficacy of copper oxide nanoparticles using Piper longum and Piper betle

Embryonic Toxicology Evaluation of Dental Varnish Using Titanium Oxide Nanoparticles Synthesized Using Ginger and Rosemary

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