Evaluation of diastolic dysfunction and repolarization dispersion in Behcet’s disease

Gemici, Kani; Baran, İbrahim; Güllülü, Sümeyye; Kazazoğlu, Ali Rıza; Cordan, Jale; Özer, Ziya

doi:10.1016/s0167-5273(00)00175-3

Cited by 40 publications

(36 citation statements)

References 19 publications

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“…Therefore, if these theories are true, greater QTcD could reflect diastolic dysfunction in various diseases. Indeed, several reports show that in patients with acute myocardial infarction or Behçet's disease, QT dispersion is associated with LV dilation and deterioration of diastolic function (20,25,28). However, Kors et al suggested an important point that at all electrode sites, repolarization potentials must have principally the same duration by simple electric field theory (29).…”

Section: Discussionmentioning

confidence: 99%

QT Dispersion Correlates with Systolic Rather than Diastolic Parameters in Patients Receiving Anthracycline Treatment

et al. 2004

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Objective The aim of this study was to investigate the relation of QT dispersion to left ventricular (LV) systolic and diastolic function in patients undergoing anthracycline therapy.Methods We used echocardiography to evaluate LV systolic and diastolic function and electrocardiography to evaluate QT dispersion and corrected QT dispersion (QTcD) in patients with hematological diseases, who received anthracycline therapy.Patients Seventy-two patients with hematological diseases who were receiving anthracycline treatment were enrolled in the present study.Results LV end-diastolic diameter or LV end-systolic diameter had a significant positive correlation to QTcD

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Section: Discussionmentioning

confidence: 99%

QT Dispersion Correlates with Systolic Rather than Diastolic Parameters in Patients Receiving Anthracycline Treatment

et al. 2004

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“…Using the conventional echocardiography, Gemici et al 11 documented a higher prevalence of diastolic dysfunction in patients with BD compared to the control group. An abnormal E/A ratio was detected in 31% of their studied patients and in 10% of the control group.…”

Section: Discussionmentioning

confidence: 99%

“…6,7 While some studies suggested that BD does not result in impaired left ventricular diastolic function (LVDF), [8][9][10] others have documented impaired LVDF. [11][12][13][14] One study suggested that the incidence of left ventricular diastolic dysfunction (LVDD) in BD is related to the geographic distribution of patients. 12 In a previous study, the occurrence of intracardiac thrombi, aortic valve regurgitation, and pericardial effusion in Egyptian patients with BD were documented.…”

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confidence: 99%

Assessment of Left Ventricular Diastolic Function in Egyptian Patients With Behçet’s Disease

et al. 2016

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Objectives: This study aims to evaluate left ventricular diastolic function in Egyptian patients with Behçet's disease using variable echocardiographic parameters by combining both transmitral and tissue Doppler velocities to overcome the occasional false interpretation of preload dependent transmitral parameters and to detect the correlation between various left ventricular diastolic parameters and different disease manifestations. Patients and methods: Forty patients (35 males, 5 females; mean age 31±8 years; range 19 to 52 years) with Behçet's disease and 32 age-and sexmatched healthy controls (26 males, 6 females; mean age 28±6 years; range 19 to 60 years) were enrolled. Left ventricular diastolic function was assessed using an algorithm that combined transmitral and tissue Doppler derived parameters. Results: Mean disease duration of the patients was 7.4±6 years. Left and right ventricular systolic function was normal in both groups. The transmitral E/A was <1 in six patients (15%). There was no difference between patients and controls regarding the other left ventricular diastolic parameters. Compared to patients with an E/A ratio >1, patients with E/A <1 were significantly older and had a longer disease duration (p=0.001 and p<0.001, respectively). All the other echocardiographic parameters in both groups were comparable. Conclusion: Egyptian patients with Behçet's disease have normal left ventricular diastolic function regardless of disease duration and activity.

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“…[4][5][6][7][8] To date, there have been several studies investigating the cardiac functions in BD. [9][10][11][12][13][14] In those studies, conventional echocardiography has been used for the assessment of cardiac function. However, several controversial results were obtained particularly regarding diastolic functions.…”

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confidence: 99%

“…However, several controversial results were obtained particularly regarding diastolic functions. [9][10][11][12][13][14] Hence, novel methods for more objective estimation of the cardiac functions such as tissue Doppler echocardiography (TDE) or Doppler-derived myocardial performance index (MPI) might be helpful in BD. Such as, MPI, which combines both systolic and diastolic function, 15 ventricular dyssynchrony, which indicates heterogeneity of contraction time between different myocardial segments, may give a better reflection of the global left ventricular (LV) function than conventional echocardiography, though, to our knowledge, these have not been investigated so far.…”

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confidence: 99%

Cardiovascular Involvement in Behçet's Disease

et al. 2015

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Evaluation of diastolic dysfunction and repolarization dispersion in Behcet’s disease

Cited by 40 publications

References 19 publications

QT Dispersion Correlates with Systolic Rather than Diastolic Parameters in Patients Receiving Anthracycline Treatment

QT Dispersion Correlates with Systolic Rather than Diastolic Parameters in Patients Receiving Anthracycline Treatment

Assessment of Left Ventricular Diastolic Function in Egyptian Patients With Behçet’s Disease

Cardiovascular Involvement in Behçet's Disease

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