Evaluation of embolic protection devices for fat emboli prevention

Practical Method for Prevention of Fat Embolism in Mechanical Stromal Cell Applications: IPs and IV Blood Transfusion Set

“…To minimize or eliminate this risk, it is necessary to ensure that the final product is in liquid form in cases in which it is possible to enter the systemic circulation and pass through a double filter (filter in filter) in the obtained liquid. 3 For this purpose, the indication-based protocols (IPs) defined by Copcu and Oztan should be followed in mechanical stromal-cell transfer. 4 If the final product is to be obtained in liquid form, the condensed fat should be diluted with an appropriate liquid (saline, ringer, platelet-poor-plasma, etc.)…”

“…Today, two types of filters are used in transfusion sets: 170–200 μm filters for macroaggregates and 15–40 μm filters for microaggregates. 3 Fat cells are normally 80–120 μm in size if they are not hypertrophied. 3 …”

“…Today, two types of filters are used in transfusion sets: 170-200 μm filters for macroaggregates and 15-40 μm filters for microaggregates. 3 Fat cells are normally 80-120 μm in size if they are not hypertrophied. 3 Hypertrophied cells are retained by the macroaggregate filter and the rest by the microaggregate filter.…”

“…3 Fat cells are normally 80-120 μm in size if they are not hypertrophied. 3 Hypertrophied cells are retained by the macroaggregate filter and the rest by the microaggregate filter. Therefore, we use the IV set presented in Figure 1 and in the video.…”