Evaluation of environmental conditions as a decontamination approach for SARS-CoV-2 when applied to common library, archive and museum-related materials

Richter, William R.; Sunderman, Michelle; Mera, T O; O’Brien, Kelly; Morgan, Kerri; Streams, S

doi:10.1111/jam.15468

Cited by 10 publications

(5 citation statements)

References 51 publications

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“…Various studies have been investigated the lifetime of SARS-CoV-2 on porous and non-porous surfaces. 132 The results have shown that viable viruses cannot be found on porous surfaces for minutes to hours; however, viruses may be detected on non-porous surfaces for days to weeks, according to the findings. [133][134] Because of capillary action inside pores and quicker aerosol droplet evaporation, it is possible that SARS-CoV-2 inactivation occurs more quickly on porous surfaces than on non-porous surfaces when compared with non-porous surfaces.…”

Section: Virus Elimination By Metallic Oxides Nanoparticlesmentioning

confidence: 82%

Nano-sized Metal Oxides and Their use as a Surface Disinfectant Against COVID-19: (Review and Perspective)

et al. 2022

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Contamination of surfaces has long been identified as a significant factor in viral transmission. Therefore, sustained efforts are required to address this issue. This work aims to build a scientific database on nano-sized metal oxides as intelligent materials for surface disinfection against corona viruses, synthesize and characterize nano-sized MgO, and discuss the possibility of using it in virus eradication. The MgO nanoparticle was prepared through the heating method. Meanwhile, XRD diffractometer, Scan electron microscope, and nitrogen adsorption were used to characterize the MgO nanoparticle. The synthesized MgO nanoparticle showed an average crystallite size of 18.55nm, lattice strain 0.0053, surface area 27.56 m2/g and d-spacing 2.1092. The outcomes of this review highlight the advantage and challenges of AgO, CuO, ZnO, TiO2 and MgO nanoparticles and their utilization for surface disinfection against coronaviruses.

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Section: Virus Elimination By Metallic Oxides Nanoparticlesmentioning

confidence: 82%

Nano-sized Metal Oxides and Their use as a Surface Disinfectant Against COVID-19: (Review and Perspective)

et al. 2022

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“…Having LAVs for COVID-19 is critical because LAVs could be safe, effective, and affordable for LMICs. It can be stored and transported at −20 °C but does not require −70 °C (for mRNA vaccines) due to the stability of SARS-CoV-2 [ 59 , 60 ]. Such a cold chain is currently used for the polio LAVs in the polio eradication campaign in many developing countries [ 55 ].…”

Section: Discussionmentioning

confidence: 99%

The Cold-Adapted, Temperature-Sensitive SARS-CoV-2 Strain TS11 Is Attenuated in Syrian Hamsters and a Candidate Attenuated Vaccine

Liu

Niu

et al. 2022

Viruses

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Live attenuated vaccines (LAVs) replicate in the respiratory/oral mucosa, mimic natural infection, and can induce mucosal and systemic immune responses to the full repertoire of SARS-CoV-2 structural/nonstructural proteins. Generally, LAVs produce broader and more durable protection than current COVID-19 vaccines. We generated a temperature-sensitive (TS) SARS-CoV-2 mutant TS11 via cold-adaptation of the WA1 strain in Vero E6 cells. TS11 replicated at >4 Log10-higher titers at 32 °C than at 39 °C. TS11 has multiple mutations, including those in nsp3, a 12-amino acid-deletion spanning the furin cleavage site of the S protein and a 371-nucleotide-deletion spanning the ORF7b-ORF8 genes. We tested the pathogenicity and protective efficacy of TS11 against challenge with a heterologous virulent SARS-CoV-2 D614G strain 14B in Syrian hamsters. Hamsters were randomly assigned to mock immunization-challenge (Mock-C) and TS11 immunization-challenge (TS11-C) groups. Like the mock group, TS11-vaccinated hamsters did not show any clinical signs and continuously gained body weight. TS11 replicated well in the nasal cavity but poorly in the lungs and caused only mild lesions in the lungs. After challenge, hamsters in the Mock-C group lost weight. In contrast, the animals in the TS11-C group continued gaining weight. The virus titers in the nasal turbinates and lungs of the TS11-C group were significantly lower than those in the Mock-C group, confirming the protective effects of TS11 immunization of hamsters. Histopathological examination demonstrated that animals in the Mock-C group had severe pulmonary lesions and large amounts of viral antigens in the lungs post-challenge; however, the TS11-C group had minimal pathological changes and few viral antigen-positive cells. In summary, the TS11 mutant was attenuated and induced protection against disease after a heterologous SARS-CoV-2 challenge in Syrian hamsters.

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“…Recent works report that the virus decreases its infectivity when exposed to solar radiation [20] and UV-C radiation [21,22] at ground level. Even when the virus is exposed to UV-A (the terrestrial UV radiation) over 15 min, the virus inactivation happens [23], even in aerosols [24].…”

Section: Sars-cov-2 Meteorological Parameters Effectmentioning

confidence: 99%

Air Pollution and Meteorological Parameters in SARS-CoV-2 Virus Spread and Transition

Ehsanifar¹,

Rafati²

2022

J Biomed Res Environ Sci

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The purpose of this small study is to evaluate the meteorological parameters and air pollutants on the prevalence of SARS-CoV-2 in urban areas to identify conditions that can prevent or prevent future infection waves. According to studies, all meteorological parameters are significantly associated with SARS-CoV-2 cases. (Temperature, mainly affects solar radiation, UV Index (UVI), and wind speed) as well as air pollution parameters (Especially O3, SO2, and CO), but to a lesser extent. CO, SO2, and NO2 (mobility markers that refer to human interaction) it was reported all year round. It can be inferred that meteorological phenomena mainly affect the virus, both in its spread and inactivation: High relative humidity, low temperatures, low solar radiation, and low Wind speed can cause the virus to persist in the air, then, cold and dry rainy seasons can be dangerous for people who are outdoors. CO, SO2 and NO2 can be used to predict and reduce infections in the new wave of SARS-CoV-2 transmission. Adequate outdoor face masks should be considered to prevent inhalation of air pollutants and SARS-CoV-2.

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Evaluation of environmental conditions as a decontamination approach for SARS-CoV-2 when applied to common library, archive and museum-related materials

Cited by 10 publications

References 51 publications

Nano-sized Metal Oxides and Their use as a Surface Disinfectant Against COVID-19: (Review and Perspective)

Nano-sized Metal Oxides and Their use as a Surface Disinfectant Against COVID-19: (Review and Perspective)

The Cold-Adapted, Temperature-Sensitive SARS-CoV-2 Strain TS11 Is Attenuated in Syrian Hamsters and a Candidate Attenuated Vaccine

Air Pollution and Meteorological Parameters in SARS-CoV-2 Virus Spread and Transition

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