Evaluation of etoxazole against insects and acari in vegetables in China

Li, Yongqiang; Yang, Na; Wei, Xingcun; Ling, Yun; Yang, Xinling; Wang, Qingmin

doi:10.1093/jis/14.1.104

Cited by 10 publications

(9 citation statements)

References 15 publications

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“…Guyer & Neumann (1988), when analyzed the effects of CSI in S. littoralis and H. virescens, reported a greater toxicity of chlorfluazuron compared to diflubenzuron; and the same type of chlorfluazuron larvicidal potential was observed by Kubota (1989) in T. palmi. Etoxazole obtained a greater insecticidal activity in larvae of S. exigua, P. xylostella and nymphs of A. craccivora than treatments with hexaflumuron and chlorfluazuron (Li, et al, 2014).…”

Section: Larvicidal/ninficidal Potentialmentioning

confidence: 86%

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Existing potentials in Insect Growth Regulators (IGR) for crop pest control

Apolinário

Feder

2021

RSD

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The aim of this review is to explore the potentials existing in insecticides that are considered Insect Growth Regulators (IGR) for the control of insects considered crop pests, with an observation of the main mechanisms of neuroendocrine modifications, development and viability of the species used as study models. The data search on digital platforms, as well as the screening of materials about crop pests, resulted in 74 IGR references and their potentials. The analysis of the information found demonstrated a greater use in works of compounds belonging to chitin synthesis inhibitors class; and orders such as Hemiptera, Lepidoptera, Coleoptera, Orthoptera, Thysanoptera and Diptera were represented in the studies. The main types of activities reunited were morphological and anatomical modifications, reproductive modifications, alterations in developmental stage, alterations in developmental period, ovicidal activity, larvicidal/ninficidal activity and fagoinhibition. The congregated knowledge about the main pests used as study models, the main IGRs compounds and their biological potentials allow an evaluation of their use as an informative source for crop pest control methods.

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Section: Larvicidal/ninficidal Potentialmentioning

confidence: 86%

“…CSI can be analyzed as potential larvicides using different compounds, although it is not yet certain which method of application of these substances is the most effective. known as the Florida wax scale (Eisa, et al, 1991;Perez-Farinos, et al, 1998;Khajepour, et al, 2012;Li, et al, 2014).…”

Section: Larvicidal/ninficidal Potentialmentioning

confidence: 99%

Existing potentials in Insect Growth Regulators (IGR) for crop pest control

Apolinário

Feder

2021

RSD

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“…The adults were removed after 60 eggs were laid. The protocol to investigate the activity of etoxazole against mite eggs was slightly modified from the FAO dip test . Basically, 1 mg/L stock solution of racemate mixture or etoxazole enantiomers in pure acetone was prepared and diluted in water to different concentrations for testing.…”

Section: Methodsmentioning

confidence: 99%

“…The protocol to investigate the activity of etoxazole against mite eggs was slightly modified from the FAO dip test. 18 Basically, 1 mg/L stock solution of racemate mixture or etoxazole enantiomers in pure acetone was prepared and diluted in water to different concentrations for testing. For the test, each leaf with 60 mite eggs was soaked in one of the solutions for 3 s, and then the superfluous liquid was removed by wiping.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Systemic Stereoselectivity Study of Etoxazole: Stereoselective Bioactivity, Acute Toxicity, and Environmental Behavior in Fruits and Soils

Chang

Nie

Yan

et al. 2019

J. Agric. Food Chem.

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This is the first systemic assessment of the stereoselectivity of etoxazole enantiomers. Etoxazole’s stereoselective bioactivity was assessed against target organisms (Tetranychus urticae eggs and Tetranychus cinnabarinus eggs), and its acute toxicity was assessed toward nontarget aquatic organisms (Daphnia magna and Danio rerio). Additionally, stereoselective elimination was investigated in three species of fruits (grape and strawberry grown in a greenhouse and apple grown in an open field) and in field soil. The ovicidal activity of (+)-(S)-etoxazole against Tetranychus urticae and Tetranychus cinnabarinus eggs was about 16 and 24 times higher, respectively, than that of (−)-(R)-etoxazole. Inconsistent order of etoxazole isomer toxicity was found toward different aquatic organisms: (+)-(S)-etoxazole showed nearly 8.7 times higher acute toxicity than (−)-(R)-etoxazole toward Daphnia magna, whereas (−)-(R)-etoxazole was ∼4.5 times more toxic to Danio rerio than (+)-(S)-etoxazole. Stereoselective degradation of etoxazole enantiomers showed significant variation in various fruits and field soil. The (+)-(S)-etoxazole was preferentially dissipated in grape and strawberry fruits grown under greenhouse condition, whereas (−)-(R)-etoxazole degraded faster than its antipode in apple fruits and soils under open-field condition. Overall, the stereoselectivity of etoxazole enantiomers should be fully considered in comprehensive environmental health risk in future work.

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“…8C). Chitin synthesis inhibitor activity of Etoxazole was tested against major insect pest of vegetables, beet armyworm (Spodoptera exigua), diamondback moth (Plutella xylostella), bean aphid (Aphis craccivora) and carmine spider mite (Tetranychus cinnabarinus) and its effective with LC 50 also recorded [21].…”

Section: Molecular Simulation Analysis Of Amecr-antagonist Complexmentioning

confidence: 99%

Ariadne merione ecdysone receptor (AmEcR) protein: An in silico approach for comparison of agonist and antagonist compounds

Sundaravadivelan¹,

Easwaran

Preethy

et al. 2017

Egyptian Journal of Basic and Applied Sciences

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Ecdysteroid signal transduction plays a major role in insect metamorphosis, 20-hydroxyecdysone (20E) binds to the nuclear receptor composed of the ecdysone receptor ligand binding domine (EcR-LBD) and triggers the developmental transitions. Ariadne merione ecdysone receptor (AmEcR) cDNA was amplified and partially sequenced of about 553 bp, which encodes a polypeptide of 184 amino acids (aa). The theoretical molecular weight (MW), isoelectric point (pI) and aliphatic index of the deduced AmEcR protein were predicted using BIOEDIT (v7.2.5) to be 21.192 kDa, 9.31 and 101.739 respectively. Identified ecdysone receptor gene of A. merione showed maximum similarity with Precis coenia gene. In this research, we have employed ligand-receptor engineering technique to screen a specific compound which plays antagonist role and assist to formulate an insect specific pesticide. The EcR protein 3D structure of AmEcR modeled using Schrödinger maestro and virtual screening was performed using 5554 molecules from Zinc database, where ZINC20031812 showed highest glide score of À6.257 and Etoxazole chosen on literature basis and showed best glide score À6.671. We have compared the antagonist with agonist (20E) by molecular dynamics (MD) simulation. Root Mean Square Deviation (RMSD) value of agonist and antagonist indicates the binding were stable in water with a range of distance from 2.3 to 2.6 Å, 1.8 to 2.3 Å and 1.9 to 2.3 Å with a variation over the time scale of 1 ps. Since Etoxazole and ZINC20031812 are antagonists, computationally they were more stable than 20E.

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Evaluation of etoxazole against insects and acari in vegetables in China

Cited by 10 publications

References 15 publications

Existing potentials in Insect Growth Regulators (IGR) for crop pest control

Existing potentials in Insect Growth Regulators (IGR) for crop pest control

Systemic Stereoselectivity Study of Etoxazole: Stereoselective Bioactivity, Acute Toxicity, and Environmental Behavior in Fruits and Soils

Ariadne merione ecdysone receptor (AmEcR) protein: An in silico approach for comparison of agonist and antagonist compounds

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