Evaluation of extracts of the root of Landolphia owerrience for antibacterial activity

Okeke, Malachy Ifeanyi; Iroegbu, Christian Ukwuoma; Eze, Edith Nneka; Okoli, Arinze S.; Esimone, CO

doi:10.1016/s0378-8741(01)00307-5

Cited by 284 publications

(197 citation statements)

References 11 publications

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“…Suspension [10 μL of cell suspension containing 1.1x10 4 CFU/mL of each test organism (bacterium and fungus)] was inoculated separately on sterile Muller-Hinton agar using spread plate method. The plates were allowed to dry and a sterile cork borer of diameter 6 mm was used to bore wells in the agar plates (Okeke et al, 2001). Subsequently, 50 μL of the essential oil was transferred into triplicate wells; sterile DMSO (50 μL) was the negative control for the assay while ciprofloxacin (50 μL) and ketoconazole (50 μL) served as positive controls for antibacterial and antifungal assays respectively.…”

Section: Antimicrobial Effectiveness Of Syzygium Aromaticum Oilmentioning

confidence: 99%

Phytochemical Screening and Antimicrobial Evaluation of Syzygium aromaticum Extract and Essential oil

Jimoh¹,

Arowolo²,

Alabi³

2017

Int.J.Curr.Microbiol.App.Sci

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Section: Antimicrobial Effectiveness Of Syzygium Aromaticum Oilmentioning

confidence: 99%

Phytochemical Screening and Antimicrobial Evaluation of Syzygium aromaticum Extract and Essential oil

Jimoh¹,

Arowolo²,

Alabi³

2017

Int.J.Curr.Microbiol.App.Sci

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“…Phenols are said to offer resistance to diseases and accounts for most of the anti-oxidant activity in plants. Flavonoids show anti-allergic, anti-inflammatory, anti-microbial and anti-cancer activities (Okeke et al, 2001). Antioxidant activity of A.paniculata and its constituents have been reported by various investigators which involve nicotine-induced inhibition of mitochondrial electron chain complexes and the resultant increase in nitric oxide (NO) in different parts of rats' brain was prevented by simultaneous treatment with water and ethanol extracts of A.paniculata, the water extract exhibited greater anti-oxidant activity than the ethanol extract (Das et al, 2005).…”

Section: Related Workmentioning

confidence: 99%

Phytochemical Extraction and Characterization of the Leaves of Andrographis Paniculata for Its Anti-Bacterial, Anti-Oxidant, Anti-Pyretic and Anti-Diabetic Activity

Das¹,

Srivastav²

2014

IJIRSET

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Andrographis paniculata Nees.,a member of the family Acanthaceae is a plant commonly used by the local people, for the treatment of common cold, liver diseases, snake bite and some skin infection. The aerial part of the plant was screened for their phytochemical properties and antimicrobial activity. Antimicrobial activity of leaf extract of Andrographis paniculata, was studied using different solvent like chloroform, methanol, petroleum ether and water against bacterial strains like Bacillus subtilis, Escherichia coli by disc diffusion method. Methanolic extract showed maximum inhibitory action against Escherichia coli and Bacillus subtilis respectively. Results of the phytochemical screening showed that steroids, phenols, terpenoids, alkaloids, saponins, flavonoids were the active compounds present in the plant. The plant is traditionally used for the treatment of antibacterial, antioxidant, antidiabatic, antipyretic, hepatoprotective and several infectious diseases ranging from malaria to dysentery. The medicinal value of this plant is due to the presence of active ingredients viz andrographolide and neoandrographolide which are derivatives of diterpenoids. It is a potent scavenger of a variety of reactive oxygen species including superoxide anion, nitric oxide, hydrogen peroxide. The anti-oxidant activity was determined by DPPH (2, 2-diphenyl-1-picrylhydrazyl) method. Total antioxidant capacity were determined spectrophotometrically.

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“…The minimal inhibition concentration (MIC) values were determined by using the modified microwell dilution method (Okeke et al, 2001): 100 µL of suspension containing 10 8 CFU/mL of bacteria was spread on nutrient broth (NB). In the microwell dilution method, a twofold serial dilution of the extracts was prepared by diluting with dimethylsulfoxide (10%) to achieve a decreasing concentration range of 250 to 31.25 µg/mL in the microplate.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

Unal

Mavi

Kara

et al. 2008

Pharmaceutical Biology

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The antimicrobial activities of chloroform, acetone, ethanol, and water extracts of 25 plants, mostly used as remedies against various diseases in Turkish traditional medicine, were tested against 10 pathogenic bacteria and one fungus (Candida albicans) using the disk diffusion method. Among the tested plant species, Ziziphora clinopodioides Lam (Labiatae), Thymus fallax Fisch et Mey. (Labiatae), and three Hypericum species [H. heterophyllum Vent., H. hyssopifolium Chaix. subsp. elongatum (Ledeb.) Woron var. elongatum, and H. scabrum L.] (Guttiferae) showed antimicrobial activity at a broader spectrum. In particular, chloroform, acetone, and ethanol extracts of Z. clinopodioides inhibited the growth of all microbial species. Minimal inhibition concentration values of Z. clinopodioides extracts were also found to be low. The antioxidant activity of the acetone, ethanol, and water extracts of 20 plants was also evaluated by lipid peroxidation inhibition and DPPH free radical scavenging methods. It was found that water, ethanol, and acetone extracts of Z. clinopodioides, T. fallax, three Hypericum species, Artemisia santonicum L. (Compositae), and Echinophora tenuifolia L. subsp. sibthorpiena (Umbelliferae) have strong antioxidant activities among the tested plant species. In general, there is a correlation between the antioxidant potential and total phenolic contents of the extracts. In light of the current study, it can be concluded that Z. clinopodioides and T. fallax may have potential use in the food industry as antioxidants and antimicrobial herbs, as well as pharmaceutical interest.

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Evaluation of extracts of the root of Landolphia owerrience for antibacterial activity

Cited by 284 publications

References 11 publications

Phytochemical Screening and Antimicrobial Evaluation of Syzygium aromaticum Extract and Essential oil

Phytochemical Screening and Antimicrobial Evaluation of Syzygium aromaticum Extract and Essential oil

Phytochemical Extraction and Characterization of the Leaves of Andrographis Paniculata for Its Anti-Bacterial, Anti-Oxidant, Anti-Pyretic and Anti-Diabetic Activity

Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

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