Evaluation of Factors That Have Reduced Mortality From Acute Pancreatitis Over the Past 20 Years

Bank, Simmy; Singh, Pankaj; Pooran, Nakechand; Stark, Bernard

doi:10.1097/00004836-200207000-00012

Cited by 74 publications

(36 citation statements)

References 25 publications

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“…During the last 15 years a big step was done towards the understanding and development of acute pancreatitis and at the same time the great progress in the screening methods of pancreas . In line with the other authors opinions (Bank et al, 2002), taking into account own experiences, we are convinced that the decrease of the mortality was causes by an early recognition of the severe acute severe and setting up the prompt and appropriate treatment, by the improvement of the nutritional support, early endoscopic retrograde cholangiopancreatography supplied to the accurately indicated patients, and using the effective antibiotic treatment. The International Association of Pancreatology proposed for acute pancreatitis treatment eleven recommendations (Sarr, 2003;Uhl et al, 2002), which created the framework for contemporary management of acute pancreatitis.…”

Section: Discussionsupporting

confidence: 83%

Changes in the Management of Treatment in Acute Pancreatitis Patients

Bober¹,

Kaťuchová²,

Radonák³

2012

Acute Pancreatitis

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Section: Discussionsupporting

confidence: 83%

Changes in the Management of Treatment in Acute Pancreatitis Patients

Bober¹,

Kaťuchová²,

Radonák³

2012

Acute Pancreatitis

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“…However, this relatively low mortality rate should be treated with some caution: to start, these medical centers have a long history in the area of research and treatment of acute pancreatitis in Guangdong. On the other hand, there have been large numbers of studies addressing the issue of mortality in acute pancreatitis with various etiologies; in addition, it is said that biliary pancreatitis may have a self-limiting course, while alcoholic pancreatitis is more likely to develop into severe pancreatitis as compared with other etiologies, along with a higher mortality rate [14,15,16]. For this reason, it is of great importance to point out that the predominant etiology of severe acute pancreatitis in this study was biliary tract disease (nearly 50%) which may explain the relatively low mortality rate in severe acute pancreatitis to some extent, suggesting that course and outcome of severe acute pancreatitis are somewhat determined by the underlying etiology which could be further confirmed by multivariate analysis: the biliary etiology served as a protective factor against a poor clinical outcome in patients with severe acute pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

Acute Pancreatitis in the Guangdong Province, China

et al. 2007

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Background/Aims: Many studies have recently been published on acute pancreatitis; however, few large-sample studies have been focused on the risk factors for deaths in severe acute pancreatitis. To address this issue, the present study was intended to assess etiology, severity, and mortality of acute pancreatitis in the Guangdong Province (Guangdong), China, and to analyze the risk factors responsible for deaths in severe acute pancreatitis in this large series of patients. Methods: Four tertiary medical centers located in Guangdong were involved in this retrospective study. Data of 2,342 patients with acute pancreatitis admitted to these centers from December 1990 through December 2005 were collected in a standardized form and analyzed. Results: Of the 2,342 patients (1,130 men and 1,212 women, mean age 51±18, range 4–98 years), 1,778 (76.0%) had mild pancreatitis, and 564 (24.0%) had the severe form. Biliary tract disease (47.5%) was the predominant etiology, the overall mortality rate was 5.0%, and the fatality rate in patients with severe acute pancreatitis was 20.0%. Among the deceased patients in the severe acute pancreatitis group, logistic regression analysis of variables showed that the independent risk factor for mortality was shock, while a biliary origin was a protective factor against a poor prognosis. Conclusions: In this case series, the results suggest that biliary tract disease was the main etiologic factor of acute pancreatitis in Guangdong. The majority of deaths in severe acute pancreatitis occurred within the first 14 days of admission; the only independent risk factor for mortality was systematic complication of shock.

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“…Dentro de estas, 9 fueron por complicaciones graves con elevadas tasas de morbimortalidad 19,20 . Esto indica que hay un porcentaje significativo (11%) de pacientes que se complican estando en lista de espera, escenario que es prevenible con CCTs electivas oportunas que tienen menores tasas de complicaciones que las de urgencia [21][22][23] .…”

Section: Discussionunclassified