Evaluation of fluconazole, itraconazole, and voriconazole activity on Candida albicans: A case control study

Partha, Agung Dewi Sekar Langit; Widodo, Agung Dwi Wahyu; Endraswari, Pepy Dwi

doi:10.1016/j.amsu.2022.104882

Cited by 11 publications

(7 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a recent study, one isolate (1.7%) of Candida tropicalis, which belongs to the NACS, showed resistance to fluconazole. Fluconazole, itraconazole, and voriconazole were proven to be effective in inhibiting Candida albicans growth [25]. However, other results in this study showed that several Candida albicans isolates were also resistant to fluconazole (2.6%) and voriconazole (1.3%).…”

Section: Discussionmentioning

confidence: 51%

Epidemiology and Risk Factors for Candiduria in Hospitalized Patients at Dr. Soetomo Hospital, Surabaya, Indonesia

Anggraeni¹,

Endraswari²,

Rusli³

et al. 2022

IJRP

View full text Add to dashboard Cite

Background: Candiduria can represent a variety of conditions, from sample contamination, kidney and collecting system infections, to life-threatening disseminated candidiasis. The prevalence of candiduria is significantly higher in hospitalized patients and may be associated with an increased mortality rate. Until now, most candiduria research has been done in developed countries, while the prevalence varies widely in different parts of the world.Objective: This study aimed to determine the epidemiology and risk factors for candiduria in hospitalized patients at Dr. Soetomo Hospital Surabaya from January to December 2020. Methods: This study is an observational analytic study with a cross-sectional design using medical record data and a total sample of 301 samples consisting of 185 candiduria patients and 116 non-candiduria patients. Results: Among 185 candiduria patients, most patients were female (67.6%) and dominated by the age group 45-59 years (40.5%). Candida albicans was found most commonly (42.7%). No resistance of the studied Candida species to Amphotericin B was found. The prevalence of candiduria in hospitalized patients was 0.55%. Variables that had a significant relationship with candiduria were diabetes mellitus (p=0.005; PR=1.309; 95% CI=1.089-1.575), antibiotic use (p=0.006; PR=1.4; 95% CI=1.174-1.670), and the use of an Intraurethral Catheter (IUC) (p=0.008; PR=1.292; 95% CI=1.074-1.554). While old age, female gender, and corticosteroid therapy had no association with candiduria. Conclusion:The prevalence of candiduria is 0.55%. Diabetes mellitus, antibiotic use, and the use of an Intraurethral Catheter (IUC) have a significant relationship with candiduria in hospitalized patients.

show abstract

Section: Discussionmentioning

confidence: 51%

Epidemiology and Risk Factors for Candiduria in Hospitalized Patients at Dr. Soetomo Hospital, Surabaya, Indonesia

Anggraeni¹,

Endraswari²,

Rusli³

et al. 2022

IJRP

View full text Add to dashboard Cite

show abstract

“…These findings are inconsistent with another study from southwest China ( 56 ). The high resistance rate of itraconazole compared to fluconazole and voriconazole might be due to its broader spectrum of activity, higher dosage requirements, and different mechanisms of action from other triazoles ( 57 – 59 ).…”

Section: Discussionmentioning

confidence: 99%

Six-Year Retrospective Analysis of Epidemiology, Risk Factors, and Antifungal Susceptibilities of Candidiasis from a Tertiary Care Hospital in South China

Bilal,

Zhang,

Shafiq

et al. 2023

Microbiol Spectr

View full text Add to dashboard Cite

This study provides important information on the burden of candidiasis, particularly candidemia, and the antifungal susceptibility of Candida species among hospitalized patients in an underdeveloped region of China. First, the finding that azoles were least effective against Candida species causing candidemia is particularly noteworthy, as it suggests the possibility of resistance to this class of antifungal agents.

show abstract

“…This study was complemented with MD whose results suggested that both ILs were adsorbed parallel to the Fe (110) surface. In the second study, carried out by Feng et al, 76 structures based on 1-vinyl-3-alkyl-imidazolium iodide with three different alkyl chains were evaluated: [VMIM]I: methyl, [VPIM]I: propyl, and [VBIM]I: butyl (see Table 4).…”

Section: H Somentioning

confidence: 99%

“…evaluated compounds with antifungal properties such as itraconazole ( ITC ) and fluconazole ( FC ) in their commercial forms as CIs of API 5L B steel. However, their use could imply the increase in the resistance to fungicides of determined populations of pathogenic fungi and in the long term, a potential health problem . The authors reported that C INH of 15 and 20 ppm is required to obtain IE s of 91.7 and 90.3%, respectively.…”

Section: Corrosion Inhibitorsmentioning

confidence: 99%

Current Overview of Corrosion Inhibition of API Steel in Different Environments

Díaz-Jiménez,

Gómez-Sánchez,

Likhanova

et al. 2024

ACS Omega

View full text Add to dashboard Cite

Evaluation of fluconazole, itraconazole, and voriconazole activity on Candida albicans: A case control study

Cited by 11 publications

References 21 publications

Epidemiology and Risk Factors for Candiduria in Hospitalized Patients at Dr. Soetomo Hospital, Surabaya, Indonesia

Epidemiology and Risk Factors for Candiduria in Hospitalized Patients at Dr. Soetomo Hospital, Surabaya, Indonesia

Six-Year Retrospective Analysis of Epidemiology, Risk Factors, and Antifungal Susceptibilities of Candidiasis from a Tertiary Care Hospital in South China

Current Overview of Corrosion Inhibition of API Steel in Different Environments

Contact Info

Product

Resources

About