Evaluation of fluid warmer safety using hemorheologic analysis with outdated human blood

Kim, Hee Jung; Yoo, Sung Mook; Chung, Jae Ho; Kim, Tae Sik; Lee, Sung Ho; Son, Ho Sung

doi:10.3233/ch-151926

Cited by 3 publications

(6 citation statements)

References 18 publications

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“…However, in clinical practice, it is not appropriate to wait more than 30 minutes before performing the transfusion and at 30 minutes the temperature of a packed RBC is close to 13°C. Consequently, results provided by our study are seemingly closer to clinical reality than those obtained by Kim et al [ 24 ].…”

Section: Discussionsupporting

confidence: 88%

“…However, at 300 mmHg this risk is more important with a median temperature at the outlet of the tube that reach only 33.7°C with a maximum at 34.5°C and a minimum at 32.6°C. This drop in temperature can be compared to those observed in the studies of Mateer et al [ 19 ] and Kim et al [ 24 ]. In the study of Mateer et al [ 19 ], the temperature reached 27.5 and 25.3°C with a pressure of 300 and 600 mmHg whereas the blood warmer was set at 36.7°C.…”

Section: Discussionmentioning

confidence: 56%

“…In the study of Mateer et al [ 19 ], the temperature reached 27.5 and 25.3°C with a pressure of 300 and 600 mmHg whereas the blood warmer was set at 36.7°C. The study by Kim et al [ 24 ] showed better results in term of temperature with outlet temperature at 38.1°C for a blood warmer set at 39°C and a pressure at 300mmHg. One major difference between these two studies is the mechanism of the two blood warmers and the temperature of the blood product before heating.…”

Section: Discussionmentioning

confidence: 99%

“…One major difference between these two studies is the mechanism of the two blood warmers and the temperature of the blood product before heating. In the study of Mateer et al [ 19 ], a dry heat blood warmer was used (Fenwal Model BW-5) whereas in the study of Kim et al [ 24 ] a warming plate (ThermoSens) was used. More importantly, the inlet temperatures were 13 and 23.2°C, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Kim et al [ 23 ] also did not show a significant increase in the hemolysis percentage at 37°C with a pressure of 300 mmHg as compared to the baseline level. Finally, Kim et al [ 24 ], with a blood warmer set at 39°C, showed that outdated packed RBCs transfused at 300 mmHg did not present more hemolysis than the baseline level.…”

Section: Introductionmentioning

confidence: 99%

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Pressure Infusion Cuff and Blood Warmer during Massive Transfusion: An Experimental Study About Hemolysis and Hypothermia

et al. 2016

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BackgroundBlood warmers were developed to reduce the risk of hypothermia associated with the infusion of cold blood products. During massive transfusion, these devices are used with compression sleeve, which induce a major stress to red blood cells. In this setting, the combination of blood warmer and compression sleeve could generate hemolysis and harm the patient. We conducted this study to compare the impact of different pressure rates on the hemolysis of packed red blood cells and on the outlet temperature when a blood warmer set at 41.5°C is used.MethodsPressure rates tested were 150 and 300 mmHg. Ten packed red blood cells units were provided by Héma-Québec and each unit was sequentially tested.ResultsWe found no increase in hemolysis either at 150 or 300 mmHg. By cons, we found that the blood warmer was not effective at warming the red blood cells at the specified temperature. At 150 mmHg, the outlet temperature reached 37.1°C and at 300 mmHg, the temperature was 33.7°C.ConclusionTo use a blood warmer set at 41.5°C in conjunction with a compression sleeve at 150 or 300 mmHg does not generate hemolysis. At 300 mmHg a blood warmer set at 41.5°C does not totally avoid a risk of hypothermia.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pressure Infusion Cuff and Blood Warmer during Massive Transfusion: An Experimental Study About Hemolysis and Hypothermia

et al. 2016

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The prehospital management of hypothermia — An up-to-date overview

Haverkamp

Giesbrecht

Tan

2018

Injury

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Application of warm saline injection combined with tube delivery in the prevention of PICC tube delivery difficulties and mechanical phlebitis caused by vasospasm

Wang¹,

Jia²,

Jiang³

et al. 2023

Preprint

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Purpose The objective of this study was to investigate the effectiveness of warm saline injection during PICC catheterization in preventing vasospasm and reducing mechanical phlebitis caused by vasospasm in tumor patients. Methods The study included 262 inpatients in the colorectal surgery department of our hospital who required PICC placement between January and December 2022. They were randomly divided into two groups, with the experimental group (n=132) receiving warm saline injection during catheterization and the control group (n=130) receiving conventional catheterization. The incidence of vasospasm, catheterization time, and mechanical phlebitis during PICC catheterization were compared between the two groups. Results The incidence of vasospasm in the experimental group was 1.52%, with 3.3% of patients taking more than 5 minutes to complete catheter delivery, and an incidence of mechanical phlebitis was 0.8%. In the control group, the incidence of vasospasm was 12.31%, with 15.3% of patients taking more than 5 minutes to complete catheter delivery, and an incidence of mechanical phlebitis of 9.2%. The difference between the two groups was statistically significant (P<0.05). Conclusion Warm saline injection during PICC catheterization can effectively prevent vasospasm during PICC catheterization, shorten catheterization time, and reduce the incidence of mechanical phlebitis in tumor patients. This method is simple and feasible and can be considered for clinical application.

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Evaluation of fluid warmer safety using hemorheologic analysis with outdated human blood

Abstract: The ThermoSens® fluid warmer caused no erythrocyte injury or negative effects on rheology during heating. Regarding medical device development, hemorheologic analysis can be useful for safety evaluation of medical devices that directly contact blood for temperature modulation.

Cited by 3 publications

References 18 publications

Pressure Infusion Cuff and Blood Warmer during Massive Transfusion: An Experimental Study About Hemolysis and Hypothermia

Pressure Infusion Cuff and Blood Warmer during Massive Transfusion: An Experimental Study About Hemolysis and Hypothermia

The prehospital management of hypothermia — An up-to-date overview

Application of warm saline injection combined with tube delivery in the prevention of PICC tube delivery difficulties and mechanical phlebitis caused by vasospasm

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