Evaluation of gingival blood as a minimally invasive screening tool for diabetes mellitus among 40–59-year-old adults in dental clinics: A cross-sectional study

Partheeban, Indumathi K; Chaly, Preetha Elizabeth; Priyadarshni, Indra; Junaid, Mohammed; Nijesh, J E; Vaishnavi, S

doi:10.4103/ijdr.ijdr_304_16

Cited by 4 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To prevent this effect, we instructed the patients to use mouth rinse prior to blood collection. Similar to our study, an ANOVA test done by Partheeban et al also found p-values of 0.77 between GCBG and VCBG in non-diabetic patients and 0.96 between GCBG and FCBG in diabetic patients [19]. Among the 60 non-diabetic patients, there were positive correlations between FCBG and VCBG (r=0.837), VCBG and GCBG (r=0.864), and GCBG and FCBG (r=0.936), which is similar to previous studies by Patil et al [20], Parihar et al [21], and Grigoriadis et al [22].…”

Section: Discussionsupporting

confidence: 92%

Gingival Crevicular Blood Glucose as a Novel Method for Screening Diabetes Mellitus in Periodontally Compromised Patients

Patel¹,

Dave²,

Patel³

et al. 2023

Cureus

View full text Add to dashboard Cite

Introduction: Patients with periodontitis are significantly more likely to have undetected diabetes mellitus (DM). Self‑monitoring devices like glucometers provide a simple method for rapid monitoring of the glucose level in blood by utilizing a blood sample from the finger, but this method requires puncturing to obtain blood. Bleeding from the gingival sulcus, obtained during oral hygiene examination, can be utilized for screening DM patients. Therefore, this study was performed with the aim of determining the efficacy of gingival crevicular blood as a non-invasive screening method for DM patients, as well as correlating and comparing gingival crevicular blood glucose (GCBG) levels with finger capillary blood glucose (FCBG) and fasting blood glucose (FBG) among non-diabetic and diabetic group patients. Methods: In this cross-sectional comparative study, a total of 120 participants having moderate to severe gingivitis/periodontitis with an age range of 40 to 65 years were divided into two groups on the basis of FBG range taken from an antecubital vein: non-diabetic (≤126, n=60) and diabetic (≥126, n=60) groups. Blood oozing during the routine periodontal examination from the periodontal pocket was recorded using a test strip of a glucose self-monitoring device (AccuSure ® Simple) as GCBG. Concomitantly FCBG was collected from the fingertip. These three parameters were statistically analyzed using the Student's t-test and the one-way ANOVA test and correlated with Pearson's correlation coefficient for both groups. Results: The mean and standard deviation for the three parameters GCBG, FBG, and FCBG were 93.78±12.03, 89.98±13.22, and 93.08±15.56, respectively, for the non-diabetic group and 154.52±45.05, 159±47.00, and 162.23±50.60 subsequently for the diabetic group. Comparing glucose level parameters among the non-diabetic and diabetic groups suggests a significant difference with the p-value <0.001*(inter-group). ANOVA test was done for both groups suggesting no significant difference among these three methods of measuring blood glucose level, where the p-value found was 0.272 for the non-diabetic and 0.665 for the diabetic group (intra-group comparison). Pearson's correlation values suggested a good positive correlation for the non-diabetic group, with parameters GCBG and FBG (r=0.864), GCBG and FCBG (r=0.936), and FBG and FCBG (r=0.837). The diabetic group's Pearson's correlation suggested a highly significant positive correlation between three different methods in which GCBG and FBG (r=0.978), GCBG and FBG (r=0.977), and FBG and FCBG (r= 0.982). Conclusion: Blood oozing from the periodontal pocket during routine oral hygiene examination can be utilized by dental healthcare professionals to screen pre-diabetic patients which can be used as a simple and less invasive method for DM patients.

show abstract

Section: Discussionsupporting

confidence: 92%

Gingival Crevicular Blood Glucose as a Novel Method for Screening Diabetes Mellitus in Periodontally Compromised Patients

Patel¹,

Dave²,

Patel³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

Gingival crevicular glucose estimation and patient’s perception of pain during routine dental examination - a concept based on a novel patented periodontal device

AlQahtani¹,

Khader²,

Javali³

2023

VOJNOSANIT PREGL

View full text Add to dashboard Cite

Background/Aim. Diabetes mellitus is a common metabolic disease-causing high mortality and morbidity worldwide. So, physicians need to identify this condition early to implement prevention strategies. The study aimed to test the concept of a novel periodontal device that can be attached to a glucose monitoring device as an innovative tool to screen for periodontitis and diabetes mellitus simultaneously during a routine dental examination. Therefore, correlation of blood glucose between the conventional finger-prick blood glucose (FPBG) and gingival crevicular blood glucose (GCBG) method, along with estimation of patient's pain perception by visual analogue scale (VAS). Methods. A crosssectional comparative study was conducted among 250 participants whose GCBG and FPBG were estimated. VAS score scale was recorded for each patient immediately after the procedure. Results. The mean GCBG value was 151.19 ? 42.64 mg/dL, while mean FPBG was 150.48 ? 42.95 mg/dL, showing a high Pearson's correlation (r=0.9932; p< 0.00001). Mann-Whitney U for VAS score between both the groups showed a statistically significant difference (p < 0.00001). Conclusion. The GCBG method was well tolerated by patients, and highly correlated with peripheral blood glucose levels. The proposed concept of the novel periodontal device appeared to be a feasible option for examining periodontium and screening diabetes simultaneously in dental clinics.

show abstract

Estimation of Gingival Crevicular Blood as Noninvasive Method to Determine the Blood Glucose Level: A Comparative Study

Dash,

Ramanna,

Varghese

et al. 2023

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

Evaluation of gingival blood as a minimally invasive screening tool for diabetes mellitus among 40–59-year-old adults in dental clinics: A cross-sectional study

Abstract: Gingival blood glucometry can be used as a minimally invasive screening tool for diabetes mellitus in dental clinics.

Cited by 4 publications

References 0 publications

Gingival Crevicular Blood Glucose as a Novel Method for Screening Diabetes Mellitus in Periodontally Compromised Patients

Gingival Crevicular Blood Glucose as a Novel Method for Screening Diabetes Mellitus in Periodontally Compromised Patients

Gingival crevicular glucose estimation and patient’s perception of pain during routine dental examination - a concept based on a novel patented periodontal device

Estimation of Gingival Crevicular Blood as Noninvasive Method to Determine the Blood Glucose Level: A Comparative Study

Contact Info

Product

Resources

About