Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy

Abstract

Objectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients receiving partial exchange blood transfusion and transfusion of packed cells without exchange. Methods. One hundred and twenty-five severely anemic antenatal mothers were admitted from outpatient service. Partial exchange transfusion was given to sixty-six patients while fifty-nine received transfusion of packed cells with frusemide cover. Results. The two groups were comparable in terms of age, height, weight, religion, diet, education, occupation of self and husband, and income. Hemoglobin level in Group 1 was comparatively less than Group 2 at prelevel (5.2 ± 1.5 versus 6.6 ± 2.3, P = 0.001) and postlevel (7.2 ± 1.5 versus 8.6 ± 1.8, P = 0.001), respectively, but there was no significant difference between the two modes of transfusion (2.09 ± 1.6 versus 2.01 ± 1.5, P = 0.78). Conclusion. The study produced an equally significant improvement in hematological parameters in partial exchange and packed cell transfusion. Platelet counts were significantly less in partial exchange as compared with packed cell transfusion.

Study on Trends of Anaemia Prevalence: Reduced Prevalence: Myth or Reality

“…(8,9) The high prevalence of anaemia in this study is probably related to the low socioeconomic status of the women, which may have impact on their nutritional status and health seeking behaviour. (3,5) The prevalence of anaemia in this study is much higher than the 56.0% quoted by WHO for prevalence of anaemia in Africa based on the 1988 data. (4) implying that situation is still alarming.…”

“…The prevalence of anaemia in this study was 91.42%, which is in the much higher range when compared to findings from other studies in Nigeria. (2,3,4,5,6,7) and from countries in South Eastern Africa. (8,9) The high prevalence of anaemia in this study is probably related to the low socioeconomic status of the women, which may have impact on their nutritional status and health seeking behaviour.…”

Prevalence of Iron Deficiency Anemia in Pregnant Women of District Mardan, Pakistan

“…Anaemia is associated with increased pre-term labour (28.2%), pre-eclampsia (31.2%) and maternal sepsis [1,2]. Three types of anemia during pregnancy are severe anemia when hemoglobin concentration is less than 7.0 g/dL, moderate when hemoglobin falls between 7.0-9.9 g/dL and mild anemia when hemoglobin level range from 10.0 to 11.0 g/dL [3,4]. Anemia has a variety of converging contributing factors including nutritional, genetic, frequent labour, multiparity, abortions and infectious disease, however, iron deficiency is the cause of 75% of anemia cases [1,5,6].…”

Prevalence and Associated Factors of Anemia Among Pregnant Women Residing at High Altitude in Yemen

“…It affects the health and productivity of mothers, children, and community. Recent estimates suggest that anemia during pregnancy causes about 700,000 deaths worldwide annually [3]. The association of anemia with growth retardation and poor cognitive function of children, and work productivity are well documented [4][5].…”