Evaluation of Hepatoprotective Activity of Water-Soluble Polysaccharide Fraction of Stellaria Media L.

Gorina, Ya. V.; Сапрыкина, Э. В.; Gereng, E. A.; Перевозчикова, Т. В.; Krasnov, E. A.; Иванова, Е. В.; Файт, Е. А.; Баранова, О. В.

doi:10.1007/s10517-013-2021-8

Cited by 8 publications

(4 citation statements)

References 2 publications

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“…High levels of ALT have been attributed to the damaged structural integrity of the liver. Contrary to the findings of this study, Gorina et al [23] reported a decrease in serum activities of transaminases and bilirubin concentration in rats treated with water soluble polysaccharide fraction of S. media against CCl 4 induced hepatitis. Higher levels of globulin were observed in treated rats compared with the control group.…”

Section: Stellaria Mediacontrasting

confidence: 99%

Haematological and Biochemical Changes Observed Following Sub-chronic Administration of Crude Methanol Extracts of Stellaria media and Cajanus cajan to Wistar Rats

Oyebanji

Oridupa

Ochigbo

et al. 2018

EJMP

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Aims: Stellaria media and Cajanus cajan are nutritive plants used as food and as components of several herbal remedies either singly or in combination with other medicinal plants in Southwestern Nigeria. This study aimed to evaluate its effect on haematology and serum biochemistry after a sub-chronic administration to Wistar rats. Study Design: Wistar rats were randomly grouped into four groups and administered methanol extracts of S. media at doses of 100 mg/kg, 500 mg/kg and 1000 mg/kg respectively per os. Same grouping and treatment was carried out for methanol extract of Cajanus cajan.

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Section: Stellaria Mediacontrasting

confidence: 99%

Haematological and Biochemical Changes Observed Following Sub-chronic Administration of Crude Methanol Extracts of Stellaria media and Cajanus cajan to Wistar Rats

Oyebanji

Oridupa

Ochigbo

et al. 2018

EJMP

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“…Elevated AST level in the blood is often considered as a sign of liver damage; however, AST is not specific for the liver and may be also increased due to injuries of the heart, muscle, pancreas, kidney, or red blood cells [24]. Interestingly, SM treatment actually was found to be hepatoprotective in a liver toxicity model [25]. Overall these data suggest that Stellaria media treatment has no deleterious effect on liver function; however, a possible limitation of our study is the lack of a group receiving herbal treatment without cholesterolenriched chow.…”

Section: Discussionmentioning

confidence: 99%

Effect of Stellaria media Tea on Lipid Profile in Rats

Demján

Kiss

Siska

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Background. In folk medicine, common chickweed (Stellaria media) has traditionally been applied for the treatment of hypercholesterolemia; however, there is no firm experimental proof to support the rationale of this practice. Therefore, we aimed to assess the efficacy and safety of Stellaria media tea in hypercholesterolemic rats. Materials and Methods. Adult male Wistar rats were divided into 3 groups. The (i) control group received standard laboratory chow, the (ii) hypercholesterolemic group received cholesterol-enriched diet, and the (iii) chickweed-treated hypercholesterolemic group received cholesterol-enriched diet and 100 mg/kg body weight Stellaria media tea lyophilizate for 8 weeks. Blood samples were collected to determine serum lipid profile as well as liver and kidney function, and echocardiography was performed to assess cardiac morphology and function. Results. Cholesterol-enriched diet significantly increased serum total cholesterol, LDL- and HDL-cholesterol levels, but did not affect triacylglycerol concentrations. The addition of chickweed to the diet did not cause any significant change in serum lipid profile or body weight increase. Liver and kidney functions were unaltered and cardiac morphology and function were not changed due to Stellaria media tea lyophilizate. Conclusion. Although chickweed does not seem to be toxic, our results do not support the rationale of its use in the treatment of hypercholesterolemia.

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“…Sugarapple (Annona squamosa) (L.) [37], Madagascan Periwinkle (Cateranthus roseus) (L.) [38], tumba (Citrullus colocynthis) (L.) [39], miracle leaf (Kalanchoe pinnata) (Lam.) [40], bitter ground (Momordica charantia) [41], thai eggplant (Solanum xanthocarpum) [42], and curry leaves (Murraya koeningii) [43] are used to treat diabetes.…”

Section: Diabetesmentioning

confidence: 99%

Importance of Some Bangladeshi Ethnomedicinal Plants: A Review

Hossain

Latif

Sarker

et al. 2016

EJMP

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This review article was conducted to identify the effective ethnomedicinal plants on different diseases in the traditional culture of different regions across Bangladesh. Plants are very crucial to the human being not only for the uses in health-care, but plants are also used for various other purposes such as sources of new pharmaceuticals. Ethnomedicinal plants have been used since a long time for human healthcare and most widely used for medication system in developing and least developing countries. People of different communities in Bangladesh use medicinal plants and rely on ethnomedicine because of cost-effectiveness, acceptability, biomedical benefits and less or no side-effects. It is very likely that these phytochemicals will find their way into the arsenal of antimicrobial drugs prescribed by physicians. People in Bangladesh are becoming concerned with the over-prescription and misuse of allopathic antibiotics and antimicrobial resistance is increasing Review Articlesimultaneously in this regard. Ethnomedicine can be used as alternatives to traditional antibiotics, hence, can overcome the problems of antibiotics.

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Evaluation of Hepatoprotective Activity of Water-Soluble Polysaccharide Fraction of Stellaria Media L.

Cited by 8 publications

References 2 publications

Haematological and Biochemical Changes Observed Following Sub-chronic Administration of Crude Methanol Extracts of Stellaria media and Cajanus cajan to Wistar Rats

Haematological and Biochemical Changes Observed Following Sub-chronic Administration of Crude Methanol Extracts of Stellaria media and Cajanus cajan to Wistar Rats

Effect of Stellaria media Tea on Lipid Profile in Rats

Importance of Some Bangladeshi Ethnomedicinal Plants: A Review

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