Evaluation of Aloe vera and synbiotic as antibiotic growth promoter substitutions on performance, gut morphology, immune responses and blood constitutes of broiler chickens

Abstract

This study was performed to investigate the effect of dietary supplementation with Aloe vera (AV) powder and synbiotic as growth promoter agents on performance, gut morphology, immune responses, hematology and serum biochemistry in broilers. A total of 240-day-old male broiler chicks (Ross 308) were randomly assigned to six treatments with four replicates. Birds were offered either a corn-soybean meal basal diet (control) or the basal diet supplemented with 200 mg/kg virginiamycin (VM), 1 g/kg synbiotic (Syn), 2.5 g/kg AV (AV1), 5.0 g/kg AV (AV2) or 7.5 g/kg AV (AV3). Chickens fed any of the diets, except diet AV1, exhibited better feed conversion ratios at the 14-28 day period and higher average daily gain and duodenal villus height/crypt depth ratio at 42 days than those fed the control diet. Synbiotic supplementation caused a marked increase in the serum antibody titer against infectious bursal disease and infectious bronchitis vaccines. Feeding diet AV3 significantly increased red blood cell count and hemoglobin concentration, and decreased serum triglyceride level compared to the control group. The results suggested that dietary inclusion of 5 and 7.5 g/kg AV, similar with synbiotic supplementation, can be applied as effective alternatives to in-feed antibiotics for broiler diets.

Dietary synbiotic incorporation as an alternative to antibiotic improves growth performance, intestinal morphology, immunity and antioxidant capacity of broilers

“…Additionally, Awad et al . and Naghi Shokri et al . also found that the inclusion of synbiotics increased the villus:crypt ratio in the intestine of broilers.…”

Effects of a protected inclusion of organic acids and essential oils as antibiotic growth promoter alternative on growth performance, intestinal morphology and gut microflora in broilers

“…Detailed procedures about intestinal morphology detection were based on a previous description (Naghi Shokri et al . ).…”

“…Villus height, crypt depth and wall thickness were determined using a phase contrast microscope. Detailed procedures about intestinal morphology detection were based on a previous description (Naghi Shokri et al 2016).…”

Effects of synbiotic supplementation on growth performance, carcass characteristics, meat quality and muscular antioxidant capacity and mineral contents in broilers

“…Synbiotics would beneficially affect the host by improving the survival and persistence of living microbial dietary supplements in the gastrointestinal tract, as well as by selectively stimulating the growth and/or activating the metabolism of one or a limited number of health‐promoting bacteria . In broiler chickens, previous in vivo studies have shown that dietary supplementation with various synbiotics can promote growth rate and feed utilization efficiency, replace antibiotics, stimulate the proliferation of beneficial bacteria but inhibit the colonization of pathogenic bacteria, regulate the immune system, maintain intestinal integrity, and improve the circulating redox homeostasis and nutrient absorption . Additionally, in ovo ‐delivered synbiotics can modulate the central and peripheral lymphatic organ development in broiler chickens .…”