Evaluation of Impact of Pharmaceutical Care on Improving Knowledge and Medication Adherence in CKD Patients

Baby, Bebit; Antony, Chippy Lee; Wilson, Shivil; Xavier, Theertha; Tamilselvan, T

doi:10.22159/ijpps.2017v9i1.15053

Cited by 5 publications

(8 citation statements)

References 7 publications

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“…Similarly, studies conducted in India that enrolled both pre-dialysis and dialysis CKD patients also reported much higher sub-optimal medication adherence rates ranging from 78.0% to 98.5%. 16 , 29 – 32 Variation in the methods of assessments, study populations, level of information or education received from healthcare personnel and other patient-related factors could account for this difference. Studies have shown that sub-optimal medication adherence is associated with heightened risk for CKD progression.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of medication adherence and predictors of sub-optimal adherence among pre-dialysis patients with chronic kidney disease

Okoro

Ummate

Ohieku

et al. 2020

Medicine Access @ Point of Care

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Background: Multiple medications are required to effectively manage chronic kidney disease (CKD) and associated complications, posing the risk of poor medication adherence. Objectives: To measure medication adherence levels and to investigate the potential predictors of sub-optimal medication adherence in pre-dialysis patients with CKD. Methods: A prospective study was conducted in the medical and nephrology outpatients’ clinics in Maiduguri. Non-dialysis patients with CKD stages 1–4 aged 18 years and above were recruited through their physicians. The level of medication adherence was determined using Morisky Medication Adherence Scale. Descriptive statistics were used to summarize patients’ background characteristics. Multivariate binary logistic regression analyses were performed to investigate the significantly potential predictors of sub-optimal medication adherence at a p < 0.05. Results: There were 107 participants (48.6%) who had high medication adherence, while 97 (44.1%), and 16 (7.3%) of them had moderate adherence, and low adherence, respectively. The univariate analysis revealed that medication adherence level differed significantly with the number of medications taken daily by patients ( p < 0.05). Multivariate logistic regression analyses did not reveal a significant independent predictor of sub-optimal medication adherence. Conclusion: A majority of the participants reported sub-optimal medication adherence. The independent variables considered did not significantly predict sub-optimal medication adherence in the study population. Nevertheless, the study findings highlight the importance of clinical pharmacists’ CKD management supportive care to help improve medication adherence.

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Section: Discussionmentioning

confidence: 99%

Evaluation of medication adherence and predictors of sub-optimal adherence among pre-dialysis patients with chronic kidney disease

Okoro

Ummate

Ohieku

et al. 2020

Medicine Access @ Point of Care

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“…Available evidence shows that pharmacists' interventions, such as education and patient self-management practices among others, are critical for effective management of CKD. 11,12 Systematic reviews and meta-analyses have demonstrated significantly improved BP, renal function, medication adherence, and patient satisfaction among others due to pharmacists' interventions. [13][14][15] Meeting BP targets lower CVD occurrence, [16][17][18] and long-term BP monitoring is critical in hypertension care and may involve home BP monitoring.…”

Section: Introductionmentioning

confidence: 99%

“…The role of the pharmacist can positively impact the overall care of CKD patients through the provision of clinical services targeted toward safe and efficacious health outcomes. Available evidence shows that pharmacists' interventions, such as education and patient self‐management practices among others, are critical for effective management of CKD 11,12 . Systematic reviews and meta‐analyses have demonstrated significantly improved BP, renal function, medication adherence, and patient satisfaction among others due to pharmacists' interventions 13‐15 .…”

Section: Introductionmentioning

confidence: 99%

The impact of pharmacist‐led interventions on blood pressure control among patients with chronic kidney disease: A randomized controlled trial

Okoro

Umate

Ohieku

et al. 2022

J Am Coll Clin Pharm

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Introduction Only about 50% of patients with high blood pressure (BP) and chronic kidney disease (CKD) comorbidity have their BP controlled. Objectives The objectives of the study were to determine whether pharmacist‐led interventions reduce mean BP and improve BP control in hypertensive patients with CKD compared with usual care. Methods This 12‐month prospective, double‐blind, randomized, controlled trial was conducted at two major hospitals in Nigeria. Seventy‐four participants were randomized to the usual care arm serving as the control and 73 participants were randomized to the intervention arm. The intervention arm received home BP monitors, and pharmacological and nonpharmacological (education and training on self‐management of CKD and hypertension, and text messages) interventions. Results Baseline characteristics were similar between the intervention (n = 73) and usual care (n = 74) participants. However, significantly more females were in the intervention arm compared with the usual care arm (71.2% vs 52.7%; P = .021). Compared with the usual care arm, systolic BP (SBP) significantly decreased by 7.12 mmHg from baseline (P = .020) in the intervention arm. Higher proportions of patients gained BP control from baseline to 6 months (27.4% vs 13.5%, P = .095), and from baseline to 12 months (20.5% vs 8.1%, P = .096) in the intervention arm than the usual care. There were no statistical differences, but clinical differences were observed. Conclusion This trial demonstrates that including a clinical pharmacist in a team care setting can improve BP reduction and control in patients with CKD and hypertension. Trial registration http://clinicaltrials.gov NCT05254392.

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“…Aspects of care that respondents the most frequently ranked as excellent were staff attention to dialysis vascular access; caring of nurses; staff responsiveness to pain or discomfort; caring, helpfulness and sensitivity of dialysis staff; and ease of reaching dialysis staff by telephone. The aspects of care least frequently ranked as excellent were information provided when choosing a dialysis modality, ease of seeing a social worker, information provided about dialysis, accuracy of information from nephrologists, and accuracy of nephrologists' instructions 12 .…”

Section: Introductionmentioning

confidence: 99%

Assessment of Satisfaction Level and Quality of Life among Haemodialysis Patient’s on Dialysis Therapy

2021

MLU

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Background: Chronic diseases have become a major public health problem and the leading cause of morbidity and mortality. The burden of chronic kidney disease in India cannot be assessed accurately. QOL is an overall assessment of a person's well-being, which may include physical, emotional, and social dimensions, as well as stress level, sexual function, and self-perceived health status. Patients' quality of life (QOL) and satisfaction assessment are becoming increasingly important in health care delivery. There is evidence that better QOL and patient satisfaction might be associated with better medical outcome including reduced hospitalization and reduced mortality. The present aims are to assess the satisfaction level and quality of life among haemodialysis patients on dialysis therapy.Method: A descriptive study was chosen to assess the satisfaction level and quality of life among 100 haemodialysispatients. The structured questionnaire was used to assess the satisfaction level and quality of life among haemodialysispatients. The present study results depicts that in regards to the level of satisfaction on dialysis procedure 16%were completely dissatisfied, 37% were dissatisfied, 18% were neither satisfied nor dissatisfied, 12% were satisfied and 17% were completely satisfied. The level of quality of life among haemodialysis patients, 8% had very negative impact, 42% had negative impact, 22% had no impact, 23% had positive impact and 5% had very positive impact. Conclusion:The present study findings concluded that patients on HD were not having adequate QOL in all domains except patient satisfaction due to changes in the physiological, chemical changes occur in the kidney.

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Evaluation of Impact of Pharmaceutical Care on Improving Knowledge and Medication Adherence in CKD Patients

Cited by 5 publications

References 7 publications

Evaluation of medication adherence and predictors of sub-optimal adherence among pre-dialysis patients with chronic kidney disease

Evaluation of medication adherence and predictors of sub-optimal adherence among pre-dialysis patients with chronic kidney disease

The impact of pharmacist‐led interventions on blood pressure control among patients with chronic kidney disease: A randomized controlled trial

Assessment of Satisfaction Level and Quality of Life among Haemodialysis Patient’s on Dialysis Therapy

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