Evaluation of Intradermal and Serologic Tests for the Diagnosis of Hydatid Disease

Kagan, Irving G.; Osimani, J. J.; Varela, Jorge; Allain, Dorothy S.

doi:10.4269/ajtmh.1966.15.172

Cited by 53 publications

(36 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, hydatid cyst was confirmed in 8 patients with negative IHA test. This finding is consistent with the report of Kagon et al 13 . Hydatid cyst filled with an amorphous mass may simulates the neoplastic lesions of the liver in imaging, which creates diagnostic problem 14 .…”

Section: Discussionsupporting

confidence: 83%

Management Strategies of Major Hepatobiliary Cysts - A Retrospective Study of 145 Consecutive Patients

Ali

Rashid

Husain

et al. 1970

J. Bangladesh Coll. Phys.

View full text Add to dashboard Cite

Hepatobiliary cysts consist of a heterogeneous group of diseases that differ in cause, prevalence and manifestations. Some are found incidentally on imaging studies and tend to have a benign course. Symptomatic cysts and those become endanger to life need adequate treatment. We are reporting clinical and pathological features of 145 patients with different types of Hepatobiliary cysts along with their therapeutic approaches and outcomes. Study period was September 1997 to July 2006 (107 months). The most common was simple cyst followed by hydatid and choledochal cysts. Fifty-four (37.25%) cysts were asymptomatic and diagnosed incidentally, 75 (51.72%) had some form of symptoms; like abdominal pain, discomfort and swelling. Complications like obstructive jaundice; portal hypertension, vena caval obstruction, bronchobiliary fistula and peritonitis are noted in remaining 16 (11.03%) symptomatic patients. They were treated by partial pericystectomy with omentoplasty (44.83%), excision of the cyst with Roux-en-Y Hepaticojejunostomy or Cholangiojejunostomy (16.55%), partial pericystectomy with closure of the biliary leakage and omentoplasty (13.8%), closed total cystectomy (5.52%), right or left typical or atypical hepatectomy (14.49%), segmental deroofing and fenestration (4.8%). There were no operative deaths or major postoperative complications. The recurrence was documented in 7 patients (4.83%) in the follow up period. Three patients with hepatobiliary cystadenocarcinoma died during follow-up. In summary, Clinico-pathological features, therapeutic approaches and outcome of 145 Hepatobiliary cysts after surgery has been discussed in the light of published literatures. DOI: 10.3329/jbcps.v27i1.4238 J Bangladesh Coll Phys Surg 2009; 27: 13-21

show abstract

Section: Discussionsupporting

confidence: 83%

Management Strategies of Major Hepatobiliary Cysts - A Retrospective Study of 145 Consecutive Patients

Ali

Rashid

Husain

et al. 1970

J. Bangladesh Coll. Phys.

View full text Add to dashboard Cite

show abstract

“…Kagan (1968) considered HA as the method of choice, having an average sensitivity of 84 %. In our 75 patients with primary infection, the incidence of positives was 90 % in hepatic and 64 % in pulmonary cysts.…”

Section: The Haemagglutination (Ha) Testmentioning

confidence: 99%

Serologic evidence of the postoperative persistence of hydatid cysts in man

Matossian

Araj

1975

J. Hyg.

View full text Add to dashboard Cite

SUMMARYThe sensitivity of the haemagglutination, complement-fixation and indirect fluorescent antibody tests in the diagnosis of primary and recurrent hydatid disease is presented. In the first, diagnostic titres were obtained in 90%, 80 % and 96% of 50 patients with hepatic and 64%, 60% and 68% of 25 patients with pulmonary cysts, respectively. In the postoperative study of 62 patients, elevated titres of HA, CF and IFA antibodies in 30 led to the presumptive diagnosis of recurrent disease, confirmed later by radiological and surgical follow-ups. In the 32 others the proportion of positive reactors was 29%, 6% and 28% in HA, CF and IFA tests. These patients had no detectable cysts. This indicates that in postoperative patients a negative CF test may be of a better prognostic value in indicating absence of cysts than the HA and IFA tests.

show abstract

“…From the 1950s, these tests were complemented or gradually replaced by better methods, such as indirect haemagglutination test, bentonite and latex agglutination tests, immunoprecipitation and immunoelectrophresis. Some of these tests were quite sensitive in detecting CE, especially of the liver, but a general problem was the low degree of specificity (Kagan, 1968;Varela-Diaz and Coltorti, 1976;Rickard and Lightowlers, 1986). Later on, the repertoire of antibody tests was extended by further procedures, including the indirect fluorescent antibody test, the enzyme-linked immunosorbent assay (ELISA) and some secondary tests.…”

Section: Immunodiagnosismentioning

confidence: 99%