Objective: This study assesses the changes in the haemodynamic parameters of normotensive patients that underwent surgical extraction of impacted mandibular third molars following the administration of Lidocaine Hydrochloride (HCl) 2% with Adrenaline 1:80,000.
Materials and methods:This prospective cohort study was conducted on 168 patients who presented at the outpatient clinic with the indication(s) for surgical extraction. Patients aged 18 years and above, whose SBP was between 90 mmHg -120 mmHg and whose DBP was between 60 mmHg -80 mmHg, were included in the study. The patients' HP was taken at four different time points, namely T1, T2, T3, and T4, using a pre-calibrated non-invasive electronic BP machine (ANDON BPM) and Pulse oximeter (CA-MI).Statistical analysis was done using the Statistical Package for Social Sciences (IBM) 25.0 version. The significant level was set at a p-value of < 0.05 at a 95% confidence interval.Results: All the SBP and DBP readings showed a gradual increase in values from SBP1 and DBP1 to SBP4 and DBP4, respectively, with a statistically significant difference (p < 0.001). The highest elevation was recorded between SBP1 and SBP4 at 12.2 mmHg change as well as between DBP1 and DBP4 at 11 mmHg change. There was an increase in the values of HR throughout the surgery, showing a statistically significant difference (P < 0.001). There was a decrease in the SPO2 values throughout the surgical extraction, with a statistically significant difference of (p < 0.001).
Conclusion:This study revealed an increase in systolic blood pressure, diastolic blood pressure and heart rate but a decrease in the oxygen saturation level of the patients. There was a statistically significant change in the haemodynamic parameters across all four points studied.