Evaluation of left ventricular mass: Comparison of ultrafast computed tomography, magnetic resonance imaging, and contrast left ventriculography

Yamaoka, Osamu; Yabe, Toshikazu; Okada, Mamoru; Endoh, Shigeru; Nakamura, Yasuyuki; Mitsunami, Kenichi; Kinoshita, Masahiko; Mori, Mitsunobu; Murata, Kiyoshi; Morita, Rikushi

doi:10.1016/0002-8703(93)90536-i

Cited by 39 publications

(20 citation statements)

References 17 publications

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“…This encompasses interstudy (ie, testretest reliability) and inter-and intraobserver variability in values. Again these are very good for CMR (Table 2), 26,27,40,[47][48][49][50][51][52][53] with interstudy variability having a mean weighted SD of the difference of 7.8 g (95% CI, 15.3 g). 26,27,47,48 Mean weighted intra-and interobserver variabilities are 4.8 and 9.0 g, respectively.…”

Section: Accuracy and Reproducibilitymentioning

confidence: 85%

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Assessment of Left Ventricular Mass by Cardiovascular Magnetic Resonance

2002

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Abstract-Left ventricular hypertrophy is associated with significant excess mortality and morbidity. The study and treatment of this condition, in particular the prognostic implications of changes in left ventricular mass, require an accurate, safe, and reproducible method of measurement. Cardiovascular magnetic resonance is a suitable tool for this purpose, and this review assesses the technique in comparison with others and examines the clinical and research implications of the improved reproducibility. Key Words: myocardium Ⅲ hypertrophy Ⅲ magnetic resonance imaging T he importance of left ventricular hypertrophy (LVH) in medicine is not widely appreciated. The Framingham Study, among others, showed that increased left ventricular (LV) mass is associated with a significant excess of cardiovascular mortality and morbidity. 1 This is independent of the presence of coronary artery disease 2 or hypertension, 1 with a tripling of the mortality rate in subjects with 1-3 and without 2 either of these. The risks of coronary, peripheral, or cerebrovascular disease are also raised, even among normotensive subjects with LVH. 1,4,5 The accurate measurement of LV mass has in the past been difficult, partly because of the oblique angle at which the heart lies within the chest, its continuous movement, and the lack of a technique for imaging the whole left ventricle. Initial measurements with ECG data were surrogate markers for LV mass, with values affected by positioning of the leads, orientation of the heart, and obesity. 6 -8 Nevertheless, criteria were developed for identifying LVH with ECG 9,10 that correlated to an extent with true LVH but were insensitive and nonspecific (specificity, 6% to 56%). 11-13 Imaging techniques have now supplanted the ECG, and we review these with particular reference to cardiovascular magnetic resonance (CMR). EchocardiographyEchocardiography (echo) was a distinct advance for LV mass measurement over the ECG, with direct visualization of the myocardium and real-time imaging, and many important studies examining the prognostic effects of LVH have used this method. 1,2,14 However, obtaining good quality images is dependent on a skilled operator, patient position and anatomy, obesity, and angle of the transducer beam, 15,16 and images of sufficient quality for LV mass measurement may not be obtained in up to one third of cases. 16 -18 The assumed geometric shape for both M-mode and 2D echo may lead to error, particularly as variations in ventricular geometry affect calculated LV mass. 19 The landmark trials, such as Framingham, 1 overcame the deficiencies in accuracy and reproducibility of echo with large numbers of subjects.M-mode is the commonest echocardiographic method for measuring LV mass, the images being easier to obtain and the calculations straightforward. Although validated against postmortem mainly normal hearts, 20,21 it suffers most from the assumption of geometric shape, and this variability is reflected in the poor accuracy of the technique, with standard errors of the estima...

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Section: Accuracy and Reproducibilitymentioning

confidence: 85%

“…26,27,47,48 Mean weighted intra-and interobserver variabilities are 4.8 and 9.0 g, respectively. 47,53 By comparison, the mean weighted interstudy SD of the difference for M-mode, 2D, and 3D echo is 27. …”

Section: Accuracy and Reproducibilitymentioning

confidence: 99%

Assessment of Left Ventricular Mass by Cardiovascular Magnetic Resonance

2002

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“…4,6 However, very limited data are available comparing SPECT and a three-dimensional technique such as magnetic resonance imaging (MRI), 7 or computed tomography (CT). CT angiographic (CTA) measurements of LVM have been validated with MRI 8,9 and correlate well with two-dimensional echocardiography. 10 Quantitative analysis of SPECT MPI is commonly performed, but little clinical use has been made of the LVM data from commercial software packages.…”

Section: Introductionmentioning

confidence: 95%

Left ventricular mass from gated SPECT myocardial perfusion imaging: Comparison with cardiac computed tomography

Okwuosa

Hampole

Ali

et al. 2009

Journal of Nuclear Cardiology

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“…However, when estimates are repeated by same observer in the same person over a short period of time under the same conditions using the same instrument, most likely different values will be obtained (Semelka et al 1990a, b;Yamaoka et al 1993;Pattynama et al 1993Pattynama et al , 1995Bogaert et al 1995). The size of the data cluster determines how precise the technique is, or how reproducible the measurements are.…”

Section: Accuracy and Precisionmentioning

confidence: 99%

Cardiac Function

Bogaert

2011

Clinical Cardiac MRI

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Evaluation of left ventricular mass: Comparison of ultrafast computed tomography, magnetic resonance imaging, and contrast left ventriculography

Cited by 39 publications

References 17 publications

Assessment of Left Ventricular Mass by Cardiovascular Magnetic Resonance

Assessment of Left Ventricular Mass by Cardiovascular Magnetic Resonance

Left ventricular mass from gated SPECT myocardial perfusion imaging: Comparison with cardiac computed tomography

Cardiac Function

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