Evaluation of LV Diastolic Function From Color M-Mode Echocardiography

Abstract

early diastolic flow propagation occurs with an initial rapid velocity that abruptly decelerates to a terminal velocity. With diastolic dysfunction, the initial velocity is slower and the deceleration point occurs closer to the mitral annulus than with normal filling. A new parameter that combines these 2 effects (Vs) provides a more accurate assessment of diastolic function than the conventional propagation velocity.

Left ventricular flow propagation velocity measurement: Is it cast in stone?

“…At the one-third measurement position, the short travelling distance of the inflow jet from the MLT produced unsteady flow propagation. This had been demonstrated by another study that the V p measured close to MLT was unable to accurately identify the diastolic dysfunction [34]. In addition to the low temporal resolution of PC-MRI, a negligible or zero time delay was frequently encountered at one-third measurement position, making the estimation of V p impossible.…”

“…Since LV sizes vary with cardiac health [34] and between healthy ethnic groups [3], we had inspected V p values at a number of distances away from MLT. At the one-third measurement position, the short travelling distance of the inflow jet from the MLT produced unsteady flow propagation.…”

Presence and Implication of Temporal Nonuniformity of Early Diastolic Left Ventricular Wall Expansion in Patients With Heart Failure

“…5 The CMMD data was used to integrate the one-dimensional Euler equation as previously described. 5,8 The pressure difference at each point along with the scan line was measured relative to left atrium just above the mitral valve at the mitral annulus just before mitral valve opening by calculating the line integral between them. From the temporal profile of the IVPD, the peak IVPD from the left atrium to LV apex was calculated.…”

“…This method has been validated by comparison to direct measurements with micromanometers 15, 16 and tested clinically in patients with diastolic dysfunction, dilated cardiomyopathy, and systolic HF. 5,15,17 …”

“…3 Normally, the LV pressure falls below the left atrial pressure in early diastole, which generates intra ventricular pressure difference (IVPD) and the LV fills due to the progressive IVPD from left atrium to the LV apex. 4 Therefore, the IVPD is regarded as a measure of the strength of LV suction 5 and plays a role in the development of heart failure (HF).…”