Evaluation of malignant and benign renal lesions using diffusion-weighted MRI with multiple b values

Abstract

In addition to the ADC value, the signal intensity curve on DW images using multiple b values could be helpful for differentiation of malignant and benign renal lesions.

Optimalbvalue in diffusion-weighted imaging for differentiation of abdominal lesions

“…For liver lesions, as in our cases, optimal b value was reported as 800s/mm 2 (22). For renal lesions b600, 800, or 1000 s/mm 2 has no significant difference (23). Using b600 as a common optimal b value for abdominal lesions, some low-grade malignant liver lesions and more pancreatic malignant lesions can be differentiated than higher b values.…”

“…Our results are similar to a previous report and show that DWI can be useful for detecting pancreatic lesions, and differentiating between solid pancreatic neoplasms normal pancreatic tissue. Although some benign lesions such as liver abscesses, pyelonephritis, and pancreatitis had low ADC values, as in this study, these lesions can be readily differentiated from malignant lesions by clinical findings, and appearances on DWIs or other MRI sequences . Visual evaluation of DWI can be helpful for differentiation of malignant lesions from benign ones in the pancreas, associated pancreatitis.…”

Use of DWI in the Differentiation of Renal Cortical Tumors

“…Furthermore, many previous studies included smaller numbers of patients [13, 29] or a limited number of histopathologic subtypes [13, 19]. Other studies have based their conclusions on comparisons between malignant and benign lesions [15] or have included all nonclear cell RCC subtypes in one group for statistical analysis [16, 17, 29], thus disregarding the broad clinical and biologic differences between the subtypes.…”

DWI for Renal Mass Characterization: Systematic Review and Meta-Analysis of Diagnostic Test Performance

“…Unclear risks of bias arose in several studies that allowed different reference standards for the diagnosis of positive and negative disease. These differences in reference standards included the use of surgical pathology versus percutaneous biopsy results, the use of imaging only for lesions considered to be Bosniak category II cysts, or the use of follow-up imaging for establishing benignity of Bosniak IIF cystic lesions [5,7,[16][17][18][19]. These differences in reference standards may have allowed incorrect classification in which lesions were presumed benign but possibly were indolent malignancies (e.g., oncocytic tumors diagnosed at biopsy or on imaging follow-up of variable lengths for complex renal cystic lesions) [20].…”