Evaluation of muscle mass in obesity, prediabetes and diabetes mellitus by different equations used for the measurement of muscle mass

Dabak, Mustafa Reşat; Sevinç, Elif; Tüzün, Sabah; Gün, Emine Özel

doi:10.1016/j.dsx.2019.05.007

Cited by 9 publications

(5 citation statements)

References 16 publications

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“…Our findings corroborate the study by Dabak et al [ 40 ], which found lower values of muscle mass in obese women (BMI > 30 kg/m 2 ). Also, in the São Paulo Ageing & Health Study, older women with low muscle mass also had higher BMI values and, in addition, in the multivariate analysis, the measure of visceral adiposity was an important predictor [ 41 ].…”

Section: Discussionsupporting

confidence: 93%

Cutoff points of adiposity anthropometric indices for low muscle mass screening in middle-aged and older healthy women

Nascimento

Vieira

Gonçalves

et al. 2021

BMC Musculoskelet Disord

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Background The reduction of female sex hormones causes changes in the contractile properties of muscles as well as infiltration of fat in the muscle tissue. This results in a consequent decline in muscle strength. These changes are related to higher levels of functional impairment and physical disability. In this sense, several anthropometric indices have been used to quantify body and visceral fat. Thus, the objective of this paper is to propose cutoff points for adiposity anthropometric indices in order to identify low muscle mass, as well as to analyze the relationship between these indices and low muscle mass in middle-aged and older women. Methods Cross-sectional analytical study carried out in the Northeast of Brazil. The sample was formed by 593 women between 40—80 years old. Data collection included anthropometric assessment (BMI: Body Mass Index – WC: Waist Circumference – WHR: Waist-to-hip Ratio – WHtR: Waist-to-height Ratio – CI: Conicity Index – BAI: Body Adiposity Index – VAI: Visceral Adiposity Index – LAP: Lipid Accumulation Product), bioimpedance test and biochemical dosage. Moreover, sociodemographic data and practice of physical activity were collected. Descriptive statistics, Student's t-test, ROC curves, chi-squared and logistic regression were performed. Results The participants had a mean age of 53.11 (8.89) years, BMI of 28.49 (5.17) kg/m2 and WC of 95.35 (10.39). The prevalence of low muscle mass was 19.4%. Based on sensitivity and specificity of adiposity anthropometric indices, cutoff points were developed to identify the presence of low muscle mass (p < 0.05), except for VAI. After logistic regression, WC (OR = 6.2; CI 95%: 1.4—28.1), WHR (OR = 1.8; CI: 1.0—3.4), WHtR (OR = 5.0; CI 95%: 1.0—23.7) and BAI (OR = 14.5; CI 95%: 6.6—31.7) were associated with low muscle mass. Conclusions All anthropometric indices, except VAI, showed adequate accuracy in identifying low muscle mass in women, especially those that took into account WC. This suggests that they can become accessible and also be cost-effective strategies for assessing and managing health outcomes related to muscle mass analysis.

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Section: Discussionsupporting

confidence: 93%

Cutoff points of adiposity anthropometric indices for low muscle mass screening in middle-aged and older healthy women

Nascimento

Vieira

Gonçalves

et al. 2021

BMC Musculoskelet Disord

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“…Moreover, studies indicated that the importance of accounting for obesity when evaluating muscle mass [ 17 , 32 ]. In patients with obesity, prediabetes or diabetes, assessing muscle mass using ALM/BMI was considered more accurate than using ALM/height2 [ 33 ]. Additionally, since abdominal fat can increase without significant changes in BMI or overall weight [ 34 ], other obesity indices such as waist circumference and total fat percentage should also be taken into consideration when examining the relationship between glucose status and muscle mass.…”

Section: Discussionmentioning

confidence: 99%

Prediabetes and diabetes were attributed to the prevalence and severity of sarcopenia in middle-aged and elderly adults

Yuan,

Jia

2024

Diabetol Metab Syndr

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Background Sarcopenia and diabetes are both prevalent health problems worldwide. However, little is known about the relationship between prediabetes and the prevalence and severity of sarcopenia. Therefore, the current study aimed to explore the association between glucose status and the components of sarcopenia, including low muscle mass (LMM), low muscle strength (LMS) and low gait speed (LGS) in US adults. Methods Data from the 1999 to 2002 National Health and Nutrition Examination Survey (NHANES) were analyzed. A total of 4002 participants aged ≥ 50 years with available information on glucose status (NGR: 1939 cases; prediabetes: 1172 cases; diabetes: 891 cases) and sarcopenia were included in this study. Sarcopenia was defined according to the Foundation for National Institute of Health criteria. Muscle mass, muscle strength and gait speed were used to evaluate sarcopenia and its severity. Weighed multivariable logistic regression were used to explore the association between glucose status and the components of sarcopenia. The hypothetical population attributable fraction (PAF) for the glucose status was also calculated. Results The mean age of the cohort was 63.01 ± 9.89 years, with 49.4% being male. Multiple logistic regression analysis suggested that diabetes was an independent risk factor for sarcopenia (OR = 5.470, 95% CI 1.551–19.296) and showed a marginal association with severe sarcopenia (OR = 10.693, 95% CI 0.955–119.73) compared to NGR in men, but not in women. Additionally, prediabetes was independently associated with severe sarcopenia (OR = 3.647, 95% CI 1.532–8.697), LMS (OR = 1.472, 95% CI 1.018–2.127) and LGS (OR = 1.673, 95% CI 1.054–2.655) in the entire cohort. When stratifying by gender, we further observed that prediabetes was significantly associated with LMS in men (OR = 1.897, 95% CI 1.019–3.543) and related to LMM (OR = 3.174, 95% CI 1.287–7.829) and LGS (OR = 2.075, 95% CI 1.155–3.727) in women. HbA1c was positively associated with the prevalence of sarcopenia in men (OR = 1.993, 95% CI 1.511–2.629). PAF showed that diabetes accounted for 16.3% of observed sarcopenia cases. Maintaining NGR in the entire population could have prevented 38.5% of sarcopenia cases and 50.9% of severe sarcopenia cases. Conclusions Prediabetes and diabetes were independently associated with the prevalence and severity of sarcopenia in US population. Slowing down the progression of hyperglycemia could have prevented a significant proportion of sarcopenia cases.

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“…Estudos têm demonstrado que o EF, além de promover melhora nas capacidades físicas gerais como força, flexibilidade, resistência muscular e resistência aeróbia, é capaz de atuar prevenindo doenças sistêmicas como diabetes (REŞAT DABAK et al, 2019), bem como diminuindo sintomas de doenças que que afetam o SNC (HARVEY et al, 2018). O TAG pode ser uma dessas alterações/doenças que estão relacionadas diretamente à quebra da homeostase da atividade do SNC, a qual pode ser atenuada pela prática do EF, conforme vimos em nossos resultados.…”

Section: Discussionunclassified

Tratamento para o transtorno da ansiedade generalizada por meio da prática do exercício físico: uma revisão sistemática

Moura¹,

Moreira²,

Dias³

et al. 2022

Revista Científica Multidisciplinar Núcleo do Conhecimento

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Introdução: O exercício físico melhora variadas capacidades físicas, bem como pode promover melhora no quadro clínico de diversas doenças, entre elas as que estão relacionadas ao sistema nervoso central. Neste sentido, o objetivo deste trabalho foi produzir uma revisão sistemática da literatura para investigar se o exercício é capaz de promover melhora no quadro clínico em humanos adultos diagnosticados com transtorno de ansiedade generalizada, se há um exercício físico específico, bem como se a intensidade do mesmo está relacionada com a melhora no quadro da doença. Métodos: Estudos clínicos randomizados publicados até maio de 2019 foram pesquisados em bases de dados online (PubMed, Scopus, Web of Science, Biblioteca Cochrane, LILACS, OpenGrey e Google Scholar) após o desenvolvimento de uma declaração PICO focada na comparação entre adultos que receberam uma intervenção com a prática de exercícios físicos, regulares, planejados e supervisionados, comparados com participantes sedentários e após foi verificado os seus efeitos no quadro do transtorno da ansiedade generalizada. A pesquisa e a extração de dados foram realizadas seguindo as diretrizes do guia de redação do manuscrito PRISMA. A avaliação da qualidade e o risco de viés foram analisados seguindo o protocolo Cochrane – RoB 2.0. Resultados: Um total de 4694 artigos de referências foram recuperadas/pesquisadas, enquanto apenas seis foram consideradas elegíveis para a realização da presente revisão. A maioria dos artigos apresentou uma redução do quadro de transtorno da ansiedade generalizada a partir de uma intervenção com exercícios físicos, aeróbios e anaeróbios de moderada intensidade. Entretanto, na análise do risco de viés, todos os artigos demonstraram algumas preocupações no que diz respeito às evidências reportadas. Conclusão: O exercício físico é uma ferramenta potencial para redução do transtorno da ansiedade generalizada, sendo a intensidade moderada do exercício diretamente relacionada a uma melhora do quadro clínico da doença, independentemente do tipo: aeróbio ou anaeróbio. No entanto, é importante que pesquisas posteriores busquem investigar os mecanismos fisiológicos e neuroendócrinos relacionados a tal melhora.

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Evaluation of muscle mass in obesity, prediabetes and diabetes mellitus by different equations used for the measurement of muscle mass

Cited by 9 publications

References 16 publications

Cutoff points of adiposity anthropometric indices for low muscle mass screening in middle-aged and older healthy women

Cutoff points of adiposity anthropometric indices for low muscle mass screening in middle-aged and older healthy women

Prediabetes and diabetes were attributed to the prevalence and severity of sarcopenia in middle-aged and elderly adults

Tratamento para o transtorno da ansiedade generalizada por meio da prática do exercício físico: uma revisão sistemática

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