Evaluation of Needle Biopsy of Synovial Membrane

Wilkinson, Matthew; Jones, Brian S.

doi:10.1136/ard.22.2.100

Cited by 19 publications

(9 citation statements)

References 11 publications

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“…Rickets or osteomalacia have been described as an unusual finding in Wilson's disease (Finby and Bearn, 1958;Mehta and Shinde, 1965;Cavallino and Grossman, 1968) to which nutritional factors may have contributed (Feller and Schumacher, 1972) There was no relationship between synovial membrane findings and radiographic changes. However, the small number ofour patients included in the study and the difficulty of interpreting synovial specimens histologically (Sherman, 1951;Cruickshank, 1952;Wilkinson and Jones, 1963) make it impossible to draw general conclusions.…”

Section: Discussionmentioning

confidence: 99%

Osteoarticular changes and synovial biopsy findings in Wilson's disease.

Kaklamanis¹,

Spengos²

1973

Annals of the Rheumatic Diseases

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Section: Discussionmentioning

confidence: 99%

Osteoarticular changes and synovial biopsy findings in Wilson's disease.

Kaklamanis¹,

Spengos²

1973

Annals of the Rheumatic Diseases

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“…OA is often triggered by injury, involving reciprocal actions of joint biomechanics and biochemistry, and advancing through a cascade of degenerative events following inflammation and increased expression of catabolic cytokines and enzymes [10–12]. Advanced OA has been assessed by multiple non-imaging methods, including scoring of pain [13–15], retrieved biopsies [16], and combined (e.g. WOMAC) assessments of pain, joint stiffness and physical function [17–24].…”

Section: Introductionmentioning

confidence: 99%

Functional imaging in OA: role of imaging in the evaluation of tissue biomechanics

Neu

2014

Osteoarthritis and Cartilage

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Functional imaging refers broadly to the visualization of organ or tissue physiology using medical image modalities. In load-bearing tissues of the body, including articular cartilage lining the bony ends of joints, changes in strain, stress, and material properties occur in osteoarthritis (OA), providing an opportunity to probe tissue function through the progression of the disease. Here, biomechanical measures in cartilage and related joint tissues are discussed as key imaging biomarkers in the evaluation of OA. Emphasis will be placed on the a) potential of radiography, ultrasound, and magnetic resonance imaging to assess early tissue pathomechanics in OA, b) relative utility of kinematic, structural, morphological, and biomechanical measures as functional imaging biomarkers, and c) improved diagnostic specificity through the combination of multiple imaging biomarkers with unique contrasts, including elastography and quantitative assessments of tissue biochemistry. In comparison to other modalities, magnetic resonance imaging provides an extensive range of functional measures at the tissue level, with conventional and emerging techniques available to potentially to assess the spectrum of preclinical to advance OA.

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“…Light microscopy of the synovium in osteoarthritis reveals either no abnormality or only mild non-specific inflammatory changes in the synovium (Waine, 1958;Cooper, 1964) which may or may not be accompanied by hyperplasia of the synovial cells (Wilkinson and Jones, 1963).…”

mentioning

confidence: 99%

Ultrastructure of synovial membrane in osteo-arthritis.

Roy¹

1967

Annals of the Rheumatic Diseases

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Evaluation of Needle Biopsy of Synovial Membrane

Cited by 19 publications

References 11 publications

Osteoarticular changes and synovial biopsy findings in Wilson's disease.

Osteoarticular changes and synovial biopsy findings in Wilson's disease.

Functional imaging in OA: role of imaging in the evaluation of tissue biomechanics

Ultrastructure of synovial membrane in osteo-arthritis.

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