Evaluation of ovarian mature cystic teratomas in our clinic: 110 cases

Eskicioğlu, Fatma; Gökmen, Tülay

doi:10.5222/terh.2016.023

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…The mean volume calculated in histopathological examinations was 206.90 ± 530.90 cm 3 in the present study. In the study of Eskicioglu et al , while the average tumor volume is 128.2 cm3, we obtained that the high rate in our study using the same calculation formula (volume calculation of the ellipsoid shape ovary= longitudinal * transverse * anteroposterior diameter * 0.52) [20]. Five cases in our data had torsion in conformity with the study of Ayhan et al [16].…”

Section: Discussionsupporting

confidence: 90%

Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Atıgan

Karakaya

Çabuş

2021

Marmara Medical Journal

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Objectives: Mature cystic teratomas (MCT) originate from three germ layers: ectoderm, mesoderm and endoderm. The predictive significance of tumor markers in mature cystic teratomas is still unclear. In this study, we aimed to evaluate the predictive value of tumor markers in ovarian MCTs and histopathological contents of tumor.Materials and Methods: The data of 106 patients who were operated for ovarian MCT between 2015 and 2020 were retrospectively analysed. In addition, slides in the pathology archive were re-examined under a microscope to evaluate their histopathological contents.Results: The average age of the patients was 35.7; 26.7 in the cystectomy group and 42.1 in the oophorectomy group (p = 0.000). The ratio of tumor markers exceeding the cut off value for carbohydrate antigen (CA 19-9), lactate dehydrogenase (LDH), cancer antigen (CA 125), carcinoma antigen (CA 15-3), carcinoembryonic antigen (CEA) were 45.2%; 47.7%; 8.15%; 12.3%; 6.9%, respectively.Histopathological examination of MCTs revealed 99.1% ectoderm, 45.3% mesodermal, 39.6% endodermal origin. Conclusion:Mature cystic teratoma is a benign tumor of the reproductive age that contains three germ layers in various proportions.LDH and CA 19-9 can be a helpful tool in predicting mature cystic teratomas.

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Section: Discussionsupporting

confidence: 90%

Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Atıgan

Karakaya

Çabuş

2021

Marmara Medical Journal

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“…2.8% were bilateral and this rate was lower than in the literature. Patients with mature cystic teratoma could have pain, menstrual disorder, and some other urinary and gastrointestinal complaints due to the pressure caused by the diameter of the mature cystic teratoma, and they are mostly asymptomatic and seen during the gynecological examination or incidentally during the surgery (18)(19)(20). In this study, 25 of the patients (17.4%) had a tumor over 10 cm diameter and pain along with complaints related to the pressure while 15 (10.5) of the cases were urgently operated on because of torsion, and in 13 (9.1%) patients, MCT was incidentally seen during the ceasarean section.…”

Section: Discussionmentioning

confidence: 99%

Mature Cystic Teratoma of the Ovary; Clinicopathological Evaluation of 143 Cases in our Series, 5 Years Experience

Öğüt

Kazanci

Yapar

et al. 2021

Gynecol Obstet Reprod Med

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OBJECTIVE: Mature cystic teratoma, also known as a dermoid cyst, is the most common germ cell tumor of the ovary. In this retrospective study, it is aimed to evaluate clinicopathological findings of the patients who were operated on due to the preliminary diagnosis of dermoid cyst. STUDY DESIGN: Between May 2013 and May 2018, the findings of a total of 143 patients who were operated on with a preliminary diagnosis of dermoid cyst in our institution were analyzed retrospectively. In addition to demographic characteristics such as age, parity number and tumor size, lateralization, preoperative tumor markers, surgical procedure, presence of other pathological findings, and the rate of malignant transformation were analyzed. RESULTS: The median age of patients was 35.4 years and the ratio of nulliparous, primiparous, and multiparous patients was 46.9%, 25.2%, and 28%, respectively. The median tumor diameter was 6.7 cm, 50.3% of which were right-sided, 46.9% were left-sided and the remaining 2.8% were bilateral. Intraoperative torsion was found in 15 (10.5%) cases. The treatment consisted of 60.1% cystectomy by laparoscopy, 3.5% unilateral salpingo-oophorectomy by laparoscopy, 9.8% unilateral salpingo-oophorectomy by laparotomy, while the rate of 16.1% cases underwent hysterectomy with bilateral salpingo-oophorectomy by laparotomy, 10.5% of the cases, cysts were excised during cesarean section. As the final pathology report revealed, of 143 patients, immature teratoma was observed in five cases (3.5%), in one of them (0.7%) mixed germ cell tumor and in three of them (2.1%) borderline mucinous cancer, squamous cell carcinoma, and carcinoid tumor on mature cystic teratoma base were observed. CONCLUSION: Torsion is the most common complication with mature cystic teratoma. The size of the tumor is an important prognostic factor in terms of the malignant transformation of teratoma. Fertility sparing surgery with a minimally invasive surgical approach is available for fertility patients diagnosed with Mature cystic teratoma.

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Evaluation of ovarian mature cystic teratomas in our clinic: 110 cases

Cited by 2 publications

References 7 publications

Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Mature Cystic Teratoma of the Ovary; Clinicopathological Evaluation of 143 Cases in our Series, 5 Years Experience

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